Article
Environmental Sciences
E. Melinda Mahabee-Gittens, Ashley L. Merianos, Roman A. Jandarov, Penelope J. E. Quintana, Eunha Hoh, Georg E. Matt
Summary: By comparing hand nicotine and urinary cotinine as biomarkers, the study found that they have different associations with pediatric illnesses, potentially influenced by factors like family income. Hand nicotine levels were linked to discharge diagnoses of viral infection, pulmonary illness, and bacterial infection in children, showing a distinct association compared to urinary cotinine.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Nerea Mourino, Monica Perez-Rios, Kimberly Yolton, Bruce P. Lanphear, Aimin Chen, Jessie P. Buckley, Heidi J. Kalkwarf, Kim M. Cecil, Joseph M. Braun
Summary: This study found that postnatal serum cotinine concentrations had a greater influence on adolescent's cardiometabolic risk compared to the prenatal period, and these associations may be sex-specific.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Mariah DeSerisy, Jacob W. Cohen, Jordan D. Dworkin, Jeanette A. Stingone, Bruce Ramphal, Julie B. Herbstman, David Pagliaccio, Amy E. Margolis
Summary: This study found that prenatal secondhand smoke exposure combined with early life stress could lead to increased internalizing symptoms in children during the preschool period and slower reduction of these symptoms over time. Maternal stress levels explained this association and provide guidance for personalized prevention measures.
ENVIRONMENTAL HEALTH
(2023)
Article
Environmental Sciences
E. Melinda Mahabee-Gittens, Gang Han, Ashley L. Merianos
Summary: Children exposed to tobacco smoke at home are more likely to experience issues such as mold, pesticide use, frequent moves, and more household members compared to children with no smoke exposure.
Article
Construction & Building Technology
Clement Peng Hee Boey, Sharon Esi Duoduwa Quaye, Alex R. Cook, Wei Jie Seow, Yvette van der Eijk
Summary: This study investigated the prevalence of secondhand smoke exposure among Singapore residents and its association with respiratory symptoms, knowledge, attitudes, and behaviors. The findings indicate that secondhand smoke exposure is common in densely populated urban areas of Singapore and is associated with respiratory symptoms.
Article
Public, Environmental & Occupational Health
Shweta Vishwas Kulkarni, Phonepadith Xangsayarath, Daovieng Douangvichith, Latsamy Siengsounthone, Khatthanaphone Phandouangsy, Ly Thi-Hai Tran, Phuc Hong Le, Thanh Cong Bui
Summary: The prevalence of second-hand smoke exposure in homes and workplaces in Lao PDR is among the highest in South-East Asia, with women experiencing higher exposure at home compared to men. Lower education levels are associated with exposure at home or in the workplace, and almost all participants reported exposure to second-hand smoke in any public places.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2021)
Article
Green & Sustainable Science & Technology
Jose Precioso, Isabel Sousa, Carolina Araujo, Claudia Correia, Jose Cunha-Machado, Vania Rocha
Summary: This study examines parental smoking behaviors and their perceptions and behaviors related to secondhand smoke exposure among Portuguese children aged 4-9. The findings indicate that non-smoking parents have a higher level of agreement with smoke-free rules, greater awareness of the health risks associated with secondhand smoke, and adopt more avoidance behaviors.
Article
Public, Environmental & Occupational Health
Siwoo Kim, Yuri Lee, Changwoo Han, Min Kyung Kim, Ichiro Kawachi, Juhwan Oh
Summary: To reduce premature deaths caused by secondhand smoke, South Korea implemented changes to its health promotion act, allowing local governments to designate smoke-free areas and impose fines. After the implementation of these ordinances in 2010, the exposure to secondhand smoke decreased.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Environmental Sciences
Angel Merida-Ortega, Lizbeth Lopez-Carrillo, Karla Rangel-Moreno, Natalia Ramirez, Stephen J. Rothenberg
Summary: The study evaluated the association between tobacco exposure (active and secondhand smoke) and urinary Cd concentrations in Mexican women. Higher Cd concentrations were found in ex-smokers with SHS exposure <1 year of quitting and current smokers compared to non-smokers without SHS exposure, but the results do not support SHS exposure as a source of Cd body burden.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Respiratory System
Jing Gennie Wang, Elliot Eisenberg, Bian Liu, Corrine Hanson, Sonali Bose
Summary: Consuming a higher-quality diet may be associated with lower odds of wheezing in adolescents exposed to environmental tobacco smoke.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2022)
Article
Biochemistry & Molecular Biology
Ashley L. Merianos, Roman A. Jandarov, Mary Cataletto, E. Melinda Mahabee-Gittens
Summary: The study showed an association between tobacco smoke exposure and decreased FeNO levels in nonsmoking adolescents, with higher serum cotinine levels linked to lower odds of eosinophilic inflammation. Adolescents exposed to smoke at home also had lower FeNO levels.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY
(2021)
Article
Clinical Neurology
Ashley L. Merianos, E. Melinda Mahabee-Gittens, Kelvin Choi
Summary: This study aimed to assess the association between home tobacco smoke exposure status and inadequate sleep among U.S. school-aged children. Results indicated that children exposed to home thirdhand smoke and home secondhand smoke with thirdhand smoke had higher odds of inadequate sleep, emphasizing the need to promote parental smoking cessation to fully protect children from related risks.
Article
Environmental Sciences
Georg E. Matt, Ashley L. Merianos, Lara Stone, Chase Wullenweber, Penelope J. E. Quintana, Eunha Hoh, Nathan G. Dodder, Nicolas Lopez Galvez, E. Melinda Mahabee-Gittens
Summary: This study found that hand nicotine levels provide additional insights into children's exposure to tobacco smoke pollutants than reported child TSE and urinary biomarkers. Changes in hand nicotine levels show that consistent home smoking bans in homes of children of smokers can lower THS exposure. Hand nicotine levels may be influenced by the environmental settings in which they are collected.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Oncology
Ruixuan Wang, Jennifer LeLaurin, Allison Carrier, Benjamin Churba, Shama Karanth, Hyung-Suk Yoon, Dejana Braithwaite, Ramzi G. Salloum, Young-Rock Hong
Summary: This study found that cancer survivors are at a higher risk of secondhand smoke exposure and younger age, racial minorities, and low income are associated with higher prevalence of exposure. It is recommended to promote smoking cessation programs to protect cancer survivors and their families from the harms of secondhand smoke.
Article
Public, Environmental & Occupational Health
Sara Schiavone, Carrie Anderson, Ute Mons, Volker Winkler
Summary: The study found that countries with extensive or complete smoking bans had lower likelihood of SHS exposure in restaurants and bars compared to those with partial bans. Additionally, SHS exposure in restaurants and bars decreased significantly between 2014 and 2017.
PREVENTIVE MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Neerav Goyal, Max Hennessy, Erik Lehman, Wenxue Lin, Antonio Agudo, Wolfgang Ahrens, Stefania Boccia, Paul Brennan, Hermann Brenner, Gabriella Cadoni, Cristina Canova, Chu Chen, David Conway, Maria Paula Curado, Luigino Dal Maso, Alexander W. Daudt, Valeria Edefonti, Eleonora Fabianova, Leticia Fernandez, Silvia Franceschi, Werner Garavello, Maura Gillison, Richard B. Hayes, Claire Healy, Rolando Herrero, Ivana Holcatova, Jossy L. Kanda, Karl Kelsey, Bo T. Hansen, Rosalina Koifman, Pagona Lagiou, Carlo La Vecchia, Fabio Levi, Guojun Li, Jolanta Lissowska, Rossana Mendoza Lopez, Daniele Luce, Gary Macfarlane, Dana Mates, Keitaro Matsuo, Michael McClean, Ana Menezes, Gwenn Menvielle, Hal Morgenstern, Kirsten Moysich, Eva Negri, Andrew F. Olshan, Tamas Pandics, Jerry Polesel, Mark Purdue, Loredana Radoi, Heribert Ramroth, Lorenzo Richiardi, Stimson Schantz, Stephen M. Schwartz, Diego Serraino, Oxana Shangina, Elaine Smith, Erich M. Sturgis, Beata Swiatkowska, Peter Thomson, Thomas L. Vaughan, Marta Vilensky, Deborah M. Winn, Victor Wunsch-Filho, Guo-Pei Yu, Jose P. Zevallos, Zuo-Feng Zhang, Tongzhang Zheng, Ariana Znaor, Paolo Boffetta, Mia Hashibe, Yuan-Chin A. Lee, Joshua E. Muscat
Summary: This study analyzed the relationship between cigarette smoking, alcohol consumption, and head and neck cancer risk factors in less developed and more developed countries. The results showed that the duration of smoking and alcohol consumption had different effects on the risk of specific cancer sites depending on the country's level of development. These findings suggest that the degree of industrialization and economic development affects the relationship between smoking, alcohol, and head and neck cancer.
Article
Oncology
Hamideh Rashidian, Maryam Hadji, Mahin Gholipour, Ahmad Naghibzadeh-Tahami, Maryam Marzban, Elham Mohebbi, Roya Safari-Faramani, Mahdieh Bakhshi, Monireh Sadat Seyyedsalehi, Bayan Hosseini, Reza Alizadeh-Navaei, Habib Emami, Ali Akbar Haghdoost, Abbas Rezaianzadeh, Abdolvahab Moradi, Alireza Ansari-Moghaddam, Azim Nejatizadeh, Soodabeh ShahidSales, Alireza Rezvani, Mohammad Hasan Larizadeh, Farid Najafi, Hossein Poustchi, Mohammad Ali Mohagheghi, Paul Brennan, Elisabete Weiderpass, Joachim Schuz, Eero Pukkala, Neal D. Freedman, Paolo Boffetta, Reza Malekzadeh, Arash Etemadi, Afarin Rahimi-Movaghar, Farin Kamangar, Kazem Zendehdel
Summary: Opium use is strongly associated with an increased risk of lung cancer, particularly small cell carcinoma. Regular opium users have a 3.6-fold higher risk of developing lung cancer compared to non-users, with a dose-response relationship observed. Female opium users have a higher risk than male users. The risk is further increased for individuals who use both opium and tobacco.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Pediatrics
Jennifer M. Lye, Julia A. Knight, Jasleen Arneja, Ryan A. Seeto, Jody Wong, Nadya Adel Khani, Jennifer D. Brooks, Robert D. Levitan, Stephen G. Matthews, Stephen J. Lye, Rayjean J. Hung
Summary: This study aimed to investigate the relationship between maternal acetaminophen use during pregnancy and cognitive development at 4 years old. Through data analysis and regression models, the study found no association between acetaminophen use and cognitive development in offspring.
PEDIATRIC RESEARCH
(2023)
Article
Oncology
Thomas Behrens, Calvin Ge, Roel Vermeulen, Benjamin Kendzia, Ann Olsson, Joachim Schuez, Hans Kromhout, Beate Pesch, Susan Peters, Luetzen Portengen, Per Gustavsson, Dario Mirabelli, Pascal Guenel, Daniele Luce, Dario Consonni, Neil E. Caporaso, Maria Teresa Landi, John K. Field, Stefan Karrasch, Heinz-Erich Wichmann, Jack Siemiatycki, Marie-Elise Parent, Lorenzo Richiardi, Lorenzo Simonato, Karl-Heinz Joeckel, Wolfgang Ahrens, Hermann Pohlabeln, Guillermo Fernandez-Tardon, David Zaridze, John R. McLaughlin, Paul A. Demers, Beata Swiatkowska, Jolanta Lissowska, Tamas Pandics, Eleonora Fabianova, Dana Mates, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Paolo Boffetta, Bas Bueno-de-Mesquita, Francesco Forastiere, Kurt Straif, Thomas Bruening
Summary: Limited evidence exists regarding the exposure-effect relationship between lung-cancer risk and hexavalent chromium (Cr(VI)) or nickel. This study found that occupational exposure to Cr(VI) and nickel was associated with lung-cancer risks, particularly in men. In men, the highest quartile of cumulative exposure to CR(VI) and nickel were both significantly associated with increased odds ratios for lung cancer.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Nutrition & Dietetics
Giulia Collatuzzo, Eva Negri, Claudio Pelucchi, Rossella Bonzi, Federica Turati, Charles S. Rabkin, Linda M. Liao, Rashmi Sinha, Domenico Palli, Monica Ferraroni, Lizbeth Lopez-Carrillo, Nuno Lunet, Samantha Morais, Demetrius Albanes, Stephanie J. Weinstein, Dominick Parisi, David Zaridze, Dmitry Maximovitch, Trinidad Dierssen-Sotos, Jose Juan Jimenez-Moleon, Jesus Vioque, Manoli Garcia de la Hera, Maria Paula Curado, Emmanuel Dias-Neto, Raul Ulises Hernandez-Ramirez, Malaquias Lopez-Cervantes, Mary H. Ward, Shoichiro Tsugane, Akihisa Hidaka, Areti Lagiou, Pagona Lagiou, Zuo-Feng Zhang, Antonia Trichopoulou, Anna Karakatsani, Maria Constanza Camargo, Carlo La Vecchia, Paolo Boffetta
Summary: A meta-analysis of 16 studies found no significant association between yoghurt consumption and gastric cancer risk.
Article
Oncology
Giulia Collatuzzo, Federica Turati, Matteo Malvezzi, Eva Negri, Carlo La Vecchia, Paolo Boffetta
Summary: This study estimated the number of cancers attributable to occupational carcinogens in Italy. By using a counterfactual scenario of no exposure and considering latency, the study calculated the attributable fraction of cancer. The most prevalent occupational carcinogens were found to be UV radiation, diesel exhaust, wood dust, and silica dust. The study highlighted the substantial burden of occupational cancers in Italy and the importance of surveillance of carcinogens in the workplace.
Article
Oncology
Giulia Collatuzzo, Margherita Ferrante, Antonella Ippolito, Alessia Di Prima, Cristina Colarossi, Salvatore Scarpulla, Paolo Boffetta, Salvatore Sciacca
Summary: This study investigates cancer patterns in migrants in Southern Italy using data from the Eastern Sicily Cancer Registry. Migrants have a higher probability of developing cancer, particularly in migrant women. Cervical and lung cancer are more prevalent in migrants, while colorectal cancer is less common. Interventions should be implemented to improve the access of migrants to cancer prevention, early diagnosis, and care, with a focus on HPV vaccination, cervical cancer screening, and tobacco control.
Article
Oncology
Monireh Sadat Seyyedsalehi, Marta Rossi, Maryam Hadji, Hamideh Rashidian, Maryam Marzban, Maria Parpinel, Federica Fiori, Ahmad Naghibzadeh-Tahami, Yusuf A. Hannun, Chiara Luberto, Kazem Zendehdel, Paolo Boffetta
Summary: This study found that dietary betaine, choline, and choline-containing compounds are associated with the risk of colorectal cancer (CRC). Men who consume phosphocholine and sphingomyelin are more likely to develop CRC, while women who consume betaine have a decreased risk. Therefore, modifying the diet to increase betaine intake and managing the consumption of animal products can help reduce the risk of CRC.
Review
Oncology
Federica Teglia, Giulia Collatuzzo, Paolo Boffetta
Summary: This narrative review provides new insights and reports the current state of knowledge on occupational cancers among women, with a focus on three female working categories: beauticians and hairdressers, farmers, and healthcare workers. The inclusion of women in occupational cancer studies has become more urgent and feasible due to the changing workforce and increasing number of women employed. The review also discusses the difficulties in evaluating occupational causes of female gynecologic tumors and the potential gender differences in outcome responses.
Article
Immunology
Emanuele Sansone, Giulia Collatuzzo, Stefano Renzetti, Giorgia Ditano, Carlo Bonfanti, Emma Sala, Luigina Terlenghi, Alberto Matteelli, Mahsa Abedini, Shuffield Seyram Asafo, Paolo Boffetta, Giuseppe De Palma
Summary: Given their occupational risk profile, healthcare workers (HCWs) were prioritized for anti-SARS-CoV-2 vaccination. However, breakthrough infections remained common, especially with new SARS-CoV-2 variants of concern (VOCs) spreading rapidly in Italy. The level of anti-SARS-CoV-2 antibodies does not accurately predict protection from natural infection or vaccination, emphasizing the need for further research on susceptibility to SARS-CoV-2. This study aimed to characterize the risk profiles for SARS-CoV-2 infection in recently booster-dosed HCWs, finding that hybrid immunization (vaccine plus natural infection) elicited higher antibody levels. However, it did not always provide better protection against reinfection, highlighting the importance of the immunization profile as a virus-host interaction modifier. Despite high resistance to reinfection, there was a notable infection rate (5.6%) during the peri-booster period, reinforcing the importance of preventive measures.
Article
Nutrition & Dietetics
Hung N. Luu, Chi Thi-Du Tran, Renwei Wang, Mai Vu-Tuyet Nguyen, Mo Thi Tran, Thuy Thi-Van Tuong, Quang Hong Tran, Linh Cu Le, Huong Thi-Thu Pham, Hien Huy Vu, Nam Chi Bui, Hien Thi-Thu Ha, Dung Tuan Trinh, Claire E. Thomas, Jennifer Adams-Haduch, Liudmilla Velikokhatnaya, Robert E. Schoen, Guoxiang Xie, Wei Jia, Paolo Boffetta, Jose C. Clemente, Jian-Min Yuan
Summary: The study found that colorectal advanced adenoma is associated with alterations in ileal juice bile acids. The concentrations of hyodeoxycholic acid (HCA) species in ileal juice were significantly higher in advanced adenoma patients compared to controls. The relative abundance of ursodeoxycholic acid (UDCA) in total bile acids was significantly reduced in cases than controls.
Article
Medicine, General & Internal
Luigi De Maria, Giuseppe Delvecchio, Stefania Sponselli, Francesco Cafaro, Antonio Caputi, Gianmarco Giannelli, Pasquale Stefanizzi, Francesco Paolo Bianchi, Angela Stufano, Silvio Tafuri, Piero Lovreglio, Paolo Boffetta, Luigi Vimercati
Summary: A observational study at the University Hospital of Bari found a significant prevalence of SARS-CoV-2 breakthrough infections (BIs) among healthcare workers (HCWs) during the first year of mandatory vaccination with BNT162b2 mRNA COVID-19 vaccine. However, there were no hospitalizations or deaths. The study extended the observation period and determined the incidence, characteristics, and clinical course of SARS-CoV-2 BIs among 6213 HCWs. The results showed that SARS-CoV-2 infections can occur despite vaccination, but the clinical course is favorable.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Giulia Collatuzzo, Claudio Pelucchi, Eva Negri, Manolis Kogevinas, Jose Maria Huerta, Jesus Vioque, Manoli Garcia de la Hera, Shoichiro Tsugane, Gerson Shigueaki Hamada, Akihisa Hidaka, Zuo-Feng Zhang, M. Constanza Camargo, Maria Paula Curado, Nuno Lunet, Carlo La Vecchia, Paolo Boffetta
Summary: The association between sleep duration and stress with gastric cancer (GC) was examined. Long sleep duration (=9 h) was found to be associated with GC, while stress was associated with noncardia GC.
Article
Public, Environmental & Occupational Health
Aline F. Fares, Yao Li, Mei Jiang, M. Catherine Brown, Andrew C. L. Lam, Reenika Aggarwal, Sabine Schmid, Natasha B. Leighl, Frances A. Shepherd, Zhichao Wang, Nancy Diao, Angela S. Wenzlaff, Juntao Xie, Takashi Kohno, Neil E. Caporaso, Curtis Harris, Hongxia Ma, Matthew J. Barnett, Leticia Ferro Leal, G. Fernandez-Tardon, Manica Perez-Rios, Michael P. A. Davies, Fiona Taylor, Ben Schoettker, Paul Brennan, David Zaridze, Ivana Holcatova, Jolanta Lissowska, Beata Swiatkowska, Dana Mates, Milan Savic, Hermann Brenner, Angeline Andrew, Angela Cox, John K. Field, Alberto Ruano-Ravina, Sanjay S. Shete, Adonina Tardon, Ying Wang, Loic Le Marchand, Rui Manuel Reis, Matthew B. Schabath, Chu Chen, Hongbing Shen, Brid M. Ryan, Maria Teresa Landi, Kouya Shiraishi, Jie Zhang, Ann G. Schwartz, Ming S. Tsao, David C. Christiani, Ping Yang, Rayjean J. Hung, Wei Xu, Geoffrey Liu
Summary: This large-scale study conducted in multiple countries and regions worldwide found that the duration of smoking abstinence is associated with overall survival in patients with NSCLC, even when diagnosed at a later lung-cancer screening visit.
LANCET PUBLIC HEALTH
(2023)