Review
Chemistry, Multidisciplinary
Ehsanul Hoque Apu, Md Nafiujjaman, Srikumar Sandeep, Ashley Makela, Ali Khaleghi, Seppo Vainio, Christopher H. Contag, Jinxing Li, Ilangko Balasingham, Taeho Kim, Nureddin Ashammakhi
Summary: Advances in nanotechnology have led to the development of magnetoelectric nanoparticles (MENPs) with unique properties that can be used in various biomedical applications, including drug delivery, neural stimulation, bio-imaging, and biosensing.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Materials Science, Multidisciplinary
Sobia Noreen, Arslan Maqbool, Irsah Maqbool, Afifa Shafique, Muhammad Muzamil Khan, Yasmeen Junejo, Bilal Ahmed, Maryam Anwar, Asma Majeed, Muhammad Abbas, Muhammad Naveed, Asadullah Madni
Summary: Nanotechnology is the emerging field that focuses on controlling material configuration at a reduced scale, and multifunctional mesoporous silica nanoparticles (MSNPs) have been shown to have great potential in tumor treatment and imaging. Functionalized mesoporous silica materials have rapidly advanced in imaging and therapeutic applications.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Review
Chemistry, Multidisciplinary
Daniel Rybak, Yu-Chia Su, Yang Li, Bin Ding, Xiaoshuang Lv, Zhaoling Li, Yi-Cheun Yeh, Pawel Nakielski, Chiara Rinoldi, Filippo Pierini, Jagan Mohan Dodda
Summary: Recent advances in skin patches have brought about the development of wearable and implantable bioelectronics for long-term healthcare management and therapy. However, the design of stretchable electronic skin patches presents challenges that require a deep understanding of skin-attachable substrates, functional biomaterials, and self-powered electronics. This review discusses the evolution of skin patches, including material selection, structure design, and potential applications. Additionally, it covers topics such as stretchable sensors, self-powered patches, and integrated systems for healthcare management. The importance of addressing challenges and exploring future opportunities is emphasized, as well as the potential benefits for mankind.
Article
Polymer Science
Emma Barrett-Catton, Murial L. Ross, Prashanth Asuri
Summary: The incorporation of nanoparticles into hydrogels has been explored to enhance and add to the physical and biochemical properties of hydrogels, improving their potential for various applications.
Article
Polymer Science
Tisana Kaewruethai, Chavee Laomeephol, Yue Pan, Jittima Amie Luckanagul
Summary: Research in nanoparticles as a drug delivery system has expanded to include their use as a delivery system for bioactive substances and a diagnostic or theranostic system. Nanogels, with their colloidal stability, core-shell structure, and adjustable components, offer the potential to design multifunctional nanosystems for various biomedical applications. Enhanced features of nanogels from modified polymers and metals, such as tunable amphiphilicity, biocompatibility, stimuli-responsiveness, and sensing moieties, contribute to specificity, stability, and tracking abilities.
Review
Chemistry, Physical
Tzu-Ying Liao, Arne Biesiekierski, Christopher C. Berndt, Peter C. King, Elena P. Ivanova, Helmut Thissen, Peter Kingshott
Summary: This article explores the fabrication, performance factors, and latest developments of cold spray coatings in biomedical applications. Cold spray coatings can be widely used in the biomedical field, including biocompatibility, anti-infection, corrosion resistance, and wear resistance. In addition, the article discusses the expansion of cold spray coatings and their potential applications in antiviral fields.
PROGRESS IN SURFACE SCIENCE
(2022)
Review
Pharmacology & Pharmacy
Changshun Hou, Yung-Fu Chang, Xi Yao
Summary: Traditional adhesives have been widely used in biomedical fields, but they have limitations such as mechanical mismatch with biological tissues and weak adhesion on wet surfaces. Therefore, rational molecular engineering and structural designs are necessary to develop functional adhesive materials that can meet the specific requirements in biological systems.
Article
Nanoscience & Nanotechnology
Dan Zhao, Rui Zhang, Mengyu Xu, Xincai Xiao, Haiyan Zhao, Xianju Huang
Summary: Novel N, S-CDs with blue-green fluorescence emission were successfully synthesized and showed high sensitivity and selectivity for detecting Cu2+ and tiopronin. These CDs exhibited good biocompatibility in fluorescence imaging and excellent antimicrobial ability against gram-positive bacteria, indicating their potential for biomedical applications such as antibacterial treatment and detection of small biomolecules.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Vinda Puspasari, Aga Ridhova, Angga Hermawan, Muhamad Ikhlasul Amal, Mohammad Mansoob Khan
Summary: Rapid transmission of infectious microorganisms through person-to-person contact has significantly affected global health. Antimicrobial coating, particularly zinc oxide (ZnO) nanostructure-based coatings, provide a promising solution to prevent the growth and transmission of disease-causing microorganisms. ZnO coatings offer non-invasive, low-cost, easy-to-use, side-effect-free, and environmentally friendly options, making them highly suitable for various applications in medical devices and healthcare facilities. Challenges and future clinical practices of ZnO-based antibacterial coatings are also discussed.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Shuqin Yan, Lu Wang, Hongdou Fan, Xiufang Li, Haining You, Renchuan You, Qiang Zhang, Weilin Xu, Yingying Zhang
Summary: Silk nanofibril (SNF)-assembled microspheres with extracellular matrix (ECM)-mimicking architecture and high specific surface area were developed in this study. The microspheres demonstrated excellent biocompatibility and enhanced osteogenic differentiation-inducing ability. They could be functionalized with other molecules and nanomaterials, and showed versatile applications in protease detection and blood purification. This natural silk-based nanofibrous microsphere holds great potential as a superior biomedical material for tissue engineering, early disease diagnosis, and therapeutic devices.
Article
Chemistry, Multidisciplinary
Gwangjun Go, Ami Yoo, Hyeong-Woo Song, Hyun-Ki Min, Shirong Zheng, Kim Tien Nguyen, Seokjae Kim, Byungjeon Kang, Ayoung Hong, Chang-Sei Kim, Jong-Oh Park, Eunpyo Choi
Summary: The magnetic chitosan microscaffold is tailored for applications requiring high biocompatibility, biodegradability, and real-time imaging monitoring, providing adjustable pores and sizes based on the target application and functions such as magnetic actuation and enhanced cell adhesion using biomaterial-based magnetic particles. Demonstrated capabilities through in vitro laboratory tasks and in vivo therapeutic applications, the optimized design and fabrication of the microscaffold will advance the technology of biopolymer-based microscaffolds and micro/nanorobots.
Review
Biochemistry & Molecular Biology
Stefania Racovita, Marin-Aurel Trofin, Diana Felicia Loghin, Marius-Mihai Zaharia, Florin Bucatariu, Marcela Mihai, Silvia Vasiliu
Summary: Polybetaines are a type of smart polymers with cationic and anionic moieties, which have diverse structures and unique properties, and are widely used in nanotechnology, biomedicine, water remediation, etc.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Buket Bulut Kocabas, Azade Attar, Selcen Ari Yuka, Melda Altikatoglu Yapaoz
Summary: This study focused on the biogenic synthesis of copper oxide nanoparticles mediated by the plant species Phragmites australis. The obtained nanoparticles were characterized and their antibacterial efficacy, antioxidant abilities, and dye removal abilities were evaluated. Molecular docking analysis confirmed the binding sites and interactions of the nanoparticles with bacterial proteins. The results demonstrated the potential applications of the synthesized copper oxide nanoparticles.
BIOORGANIC CHEMISTRY
(2023)
Article
Biophysics
Kun Li, Zhen Tang, Kuangyu Song, Nicholas G. Fischer, Huihui Wang, Yunlin Guan, Yunyun Deng, Hao Cai, Sammer Ul Hassan, Zhou Ye, Ting Sang
Summary: A multifunctional nanocoating has been developed for titanium mini-implants to prevent bacterial infection and promote osseointegration. The nanocoating, consisting of antimicrobial peptides GL13K and silver nanoparticles (Ag-GL), showed excellent antibacterial properties without altering the surface morphology of the mini-implants. In vivo experiments demonstrated that the Ag-GL coating significantly enhanced osseointegration and new bone formation.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Review
Biochemistry & Molecular Biology
Rita Teixeira-Santos, Samuel Belo, Rita Vieira, Filipe J. M. Mergulhao, Luciana C. Gomes
Summary: The application of graphene-based materials in medicine shows great potential. Surface modifications can enhance their antimicrobial properties and biocompatibility with human tissues. However, further research on safety and stability is needed.