Pharmacokinetics and anti-liver fibrosis characteristics of amygdalin: Key role of the deglycosylated metabolite prunasin

Amygdalin promotes the activity of T cells to suppress the progression of HBV-related hepatocellular carcinoma via the JAK2/STAT3 signaling pathway

(2021) Ruoyu Wang et al.   BMC INFECTIOUS DISEASES

Cardioprotective potential of amygdalin against angiotensin II induced cardiac hypertrophy, oxidative stress and inflammatory responses through modulation of Nrf2 and NF‐κB activation

(2021) Yen‐Lun Kung et al.   ENVIRONMENTAL TOXICOLOGY

Pharmacokinetics-based comprehensive strategy to identify multiple effective components in Huangqi decoction against liver fibrosis

(2021) Yahang Wang et al.   PHYTOMEDICINE

A characterized saponin extract of Panax japonicus suppresses hepatocyte EMT and HSC activation in vitro and CCl4-provoked liver fibrosis in mice: roles of its modulatory effects on the Akt/GSK3β/Nrf2 cascade

(2021) Chenxi Dai et al.   PHYTOMEDICINE

Evaluation of the effective dose of amygdalin for the improvement of antioxidant gene expression and suppression of oxidative damage in mice

(2020) Sarah Albogami et al.   PeerJ

Prunus Armeniaca L. Seed Extract and Its Amygdalin Containing Fraction Induced Mitochondrial-Mediated Apoptosis and Autophagy in Liver Carcinogenesis

(2020) Samar Hosny et al.   Anti-Cancer Agents in Medicinal Chemistry

Magnetically Directed Enzyme/Prodrug Prostate Cancer Therapy Based on β-Glucosidase/Amygdalin

(2020) Jie Zhou et al.   International Journal of Nanomedicine

Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl4-induced hepatic fibrosis in rats in vivo

(2020) Ruoyu Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Metabolism of cyanogenic glycosides: A review

(2019) Peter Cressey et al.   FOOD AND CHEMICAL TOXICOLOGY

Chinese medicine CGA formula ameliorates liver fibrosis induced by carbon tetrachloride involving inhibition of hepatic apoptosis in rats

(2018) Huajie Tian et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chinese medicine CGA formula ameliorates DMN-induced liver fibrosis in rats via inhibiting MMP2/9, TIMP1/2 and the TGF-β/Smad signaling pathways

(2016) Xue-mei Li et al.   ACTA PHARMACOLOGICA SINICA

Amygdalin, quackery or cure?

(2016) Roman A. Blaheta et al.   PHYTOMEDICINE

A sensitive LC–MS/MS method for simultaneous determination of amygdalin and paeoniflorin in human plasma and its application

(2014) Xiaobing Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Phylogenetic and Functional Analysis of Gut Microbiota of a Fungus-Growing Higher Termite: Bacteroidetes from Higher Termites Are a Rich Source of β-Glucosidase Genes

(2014) Meiling Zhang et al.   MICROBIAL ECOLOGY

Determination and Pharmacokinetics of Amygdalin in Rats by LC-MS-MS

(2013) X.-b. Li et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Metabolic Pharmacokinetics in Rats: Differences between Pure Amygdalin and Amygdalin in a Decoction of Peach Seeds

(2012) Jianbo Chen et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Amygdalin inhibits angiogenesis in the cultured endothelial cells of diabetic rats

(2012) Shahnaz Khaghani et al.   Indian Journal of Pathology and Microbiology