Article
Food Science & Technology
Shan He, Yang Zhang, Yang Yuan, Muhammad Adil Farooq, Muhammad Shoaib Fayyaz, Dongxiao Su, Qinzhu Zeng, Abdul Rahaman
Summary: This study aimed to extract polyphenols from three major seaweed species found in Guangdong, China. It was found that Sargassum thunbergii had the highest polyphenol content. Gas chromatography-mass spectrometry analysis revealed that Undaria pinnatifida suringar contained gallic acid and arbutin as its major components.
FOOD SCIENCE & NUTRITION
(2022)
Article
Chemistry, Applied
Qi-Wu Zhong, Tao-Shun Zhou, Wen-Hui Qiu, Ya-Kun Wang, Qiao-Li Xu, Song-Ze Ke, Si-Jia Wang, Wei-Hua Jin, Jian-Wei Chen, Hua-Wei Zhang, Bin Wei, Hong Wang
Summary: The brown seaweed Undaria pinnatifida polysaccharides have shown potential hypoglycemic effects by reducing postprandial and induced hyperglycemia through improved glucose uptake and insulin resistance. These polysaccharides could be a promising agent for diabetes treatment.
Article
Environmental Sciences
Yoichi Sato, Takayuki Fujiwara, Hikaru Endo
Summary: This study investigated the effect of density on the survival rate, biomass production, profit, and morphological features of kelp. The results showed that survival rate was high and biomass production increased with increasing density. Profit also increased until a certain density threshold. The optimal density range for maximizing both profit and food quality was found to be 80-120 individuals per meter.
FRONTIERS IN MARINE SCIENCE
(2023)
Review
Food Science & Technology
Harshani Nadeeshani, Amira Hassouna, Jun Lu
Summary: Isolation and utilization of seaweed proteins have become a novel trend globally due to the increasing demand for healthy non-animal proteins. The attention of scientific community is on the protein derived from seaweed Undaria pinnatifida for its high nutritional quality and bioactivity. The potential food applications of U. pinnatifida-derived proteins include nutritional components, food ingredients, alternative meat products, and animal feed, with various bioactivities such as antioxidant and antihypertensive effects.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Panpan Zhang, Jinhui Jia, Pingrui Jiang, Weiyun Zheng, Xiangfei Li, Shuang Song, Chunqing Ai
Summary: This study found that polysaccharides from edible brown seaweed can improve fat deposition and inflammatory response in mice, regulate gut microbiota dysbiosis, and compound polysaccharides have a better effect. This is important for the application of edible brown seaweed in health foods.
Article
Construction & Building Technology
Houssam Affan, Karim Touati, Mohammed-Hichem Benzaama, Daniel Chateigner, Yassine El Mendili
Summary: Stranded seaweed poses a serious threat to coastal areas when the tide recedes. This study investigated the potential use of Sargassum mitucum seaweed fiber in building construction. The results showed that a cob made with Sargassum muticum algae exhibited better thermal and hygroscopic properties compared to a cob made with flax fiber. The study also highlighted the global issue of sargassum algae expansion and suggested that utilizing stranded algae could improve the mechanical and hygrothermal performance of cob-based materials.
Review
Agriculture, Multidisciplinary
Xiping Wang, Caoxing Huang, Xiaoting Fu, You-Jin Jeon, Xiangzhao Mao, Lei Wang
Summary: This review provides an overview of the current research status of Sargassum fusiforme, analyzing its active constituents and summarizing cutting-edge research and scientific issues in antioxidant, anti-inflammatory, antitumor effects, etc. It offers a reference for further development and utilization of S. fusiforme resources.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Food Science & Technology
Ping Shen, Yue Gu, Chunxu Zhang, Chenghang Sun, Lei Qin, Chenxu Yu, Hang Qi
Summary: The study found that polyphenolic compounds from seaweeds can effectively remove oxidants, with Ascophyllum nodosum showing the highest antioxidant activity and protecting against oxidative damage. 12 polyphenolic compounds were preliminarily identified through mass spectrometry analysis, and significant differences in the content and variety of polyphenolics were found in the evaluated seaweeds.
Article
Biotechnology & Applied Microbiology
N. Gonzalez-Ballesteros, N. Florez-Fernandez, M. D. Torres, H. Dominguez, M. C. Rodriguez-Arguelles
Summary: Crude fucoidans extracted from Sargassum muticum using hot water extraction were utilized in the synthesis of gold nanoparticles, with an optimization process to achieve homogeneous nanoparticles. A fucoidan fraction with higher sulfate content was obtained during extraction, containing additional beneficial components. The synthesized nanoparticles were thoroughly characterized to ensure their performance.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2021)
Article
Engineering, Environmental
Noelia Florez-Fernandez, Marta Illera, Marta Sanchez, Pablo Lodeiro, Maria Dolores Torres, Maria Elvira Lopez-Mosquera, Manuel Soto, Manuel Sastre de Vicente, Herminia Dominguez
Summary: This study investigates a novel biorefinery scheme for comprehensive valorization of Sargassum muticum by producing a Sap fraction with plant biostimulant potential through initial pressing and subsequent autohydrolysis treatment, high-yield biogas, and the possibility of preparing adsorbents from waste solids.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Biotechnology & Applied Microbiology
M. L. Balquinta, F. G. Dellatorre, S. C. Andres, G. Lorenzo
Summary: The aim of this study was to investigate the effects of environmental conditions, especially pH, and flour level on the rheological, structural, and antioxidant properties of model aqueous systems. The results showed that the level of flour mainly controlled the linear viscoelastic range of the suspensions, while the pH significantly affected the mechanical spectra. The power-law model satisfactorily fitted the flow behavior of the suspensions.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Biotechnology & Applied Microbiology
Jose Avila-Peltroche, Boo Yeon Won, Tae Oh Cho
Summary: A simple and effective protocol for the isolation, culture, and whole plant regeneration of U. pinnatifida protoplasts was established in this study. The use of commercially available enzymes and suitable incubation conditions resulted in high protoplast yields and successful regeneration. This protocol is more efficient and cost-effective than previous methods, and has the potential to be used for genetic manipulation and tissue culture in algae.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2022)
Article
Agricultural Engineering
J. Queffelec, N. Florez-Fernandez, H. Dominguez, M. D. Torres
Summary: Microwave hydrothermal processing was used to extract valuable components from U. pinnatifida, with different processing conditions impacting antioxidant properties and content of minerals, proteins, and oligosaccharides. The most suitable temperature for extracting alginates was found to be 160 degrees C, showing potential for non-food applications after incorporation into alginate matrices. Selected extracts exhibited promising biological activities against human cancer cell lines after an intensification stage, with high cellular inhibition percentages observed.
BIORESOURCE TECHNOLOGY
(2021)
Article
Food Science & Technology
Tania Ferreira-Anta, Maria Dolores Torres, Herminia Dominguez, Noelia Florez-Fernandez
Summary: Seaweeds contain various bioactive compounds of interest to the food industry, such as phenolic compounds, polysaccharides, proteins, and vitamins. Green extraction technologies, such as pressurized hot water extraction, were used to obtain these compounds. The study found that the highest fucoidan content was recovered at 160°C, while the maximum phloroglucinol content and antioxidant activity were achieved at 220°C. Encapsulation of these bioactive fractions using mannitol was also investigated.
Article
Chemistry, Physical
Andrew Gan, Saeid Baroutian
Summary: This study found that subcritical water extraction was effective for recovering phenolics, phlorotannins, and fucoidan from New Zealand Wakame, achieving higher yields compared to conventional hot water extraction.
JOURNAL OF SUPERCRITICAL FLUIDS
(2022)
Article
Environmental Sciences
Marco Roverso, Valerio Di Marco, Gabriella Favaro, Iole Maria Di Gangi, Denis Badocco, Mirco Zerlottin, Daniele Refosco, Andrea Tapparo, Sara Bogialli, Paolo Pastore
Summary: This study investigates the presence of EDTA and Cr(III) in wastewater from tannery effluents treatment plants, and the kinetics of the exchange reaction between Fe(III) and Cr(III)-EDTA. The development of a selective method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) allows for the detection of systemic underestimation of EDTA in samples containing Cr(III)-EDTA.
Article
Engineering, Marine
Marco Munari, Alessandro Devigili, Giulia dalle Palle, Davide Asnicar, Paolo Pastore, Denis Badocco, Maria Gabriella Marin
Summary: Ocean acidification poses a growing concern for broadcast spawning species, as the reduced pH may negatively affect the functionality and interactions of gametes.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Chemistry, Analytical
Andrea Pastore, Denis Badocco, Luca Cappellin, Paolo Pastore
Summary: The dichromatism of Bromophenol blue was investigated, and it was found that the slope of the calibration curve can be changed by adjusting the concentration of Bromophenol blue.
Article
Biochemistry & Molecular Biology
Marco Roverso, Roberta Seraglia, Raghav Dogra, Denis Badocco, Silvia Pettenuzzo, Luca Cappellin, Paolo Pastore, Sara Bogialli
Summary: This study evaluated the use of single-walled carbon nanohorns (SWCNH) as a specific surface for Surface-Assisted Laser Desorption Ionization (SALDI) analysis. The optimized method provided rapid analysis of amino acids and lipids, and accurately determined the composition of fatty acids in olive oil samples without any sample treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Marta Micheletto, Elisa Gaio, Erik Tedesco, Giovanni Di Maira, Etienne Mantovan, Michela Zanella, Paolo Pastore, Marco Roverso, Gabriella Favaro, Federico Benetti
Summary: Iron deficiency is a common nutritional disorder worldwide. A granular formulation called Ferro Fosfosoma (R) was found to have good resistance to gastric digestion and enhanced iron absorption in the intestine. It also did not induce any adverse effects.
Article
Chemistry, Multidisciplinary
Marianna Tosato, Luca Lazzari, Valerio Di Marco
Summary: In this study, the complexes formed between Pb2+ and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) in aqueous solutions were reinvestigated using various techniques. The results showed significant differences in the stability and overall complex stability from previous studies, particularly with a remarkable increase in stability. These revised data are of great importance for the development of lead chelators.
Article
Biochemistry & Molecular Biology
Marianna Tosato, Marco Verona, Chiara Favaretto, Marco Pometti, Giordano Zanoni, Fabrizio Scopelliti, Francesco Paolo Cammarata, Luca Morselli, Zeynep Talip, Nicholas P. van der Meulen, Valerio Di Marco, Mattia Asti
Summary: This study evaluated the labeling performance and stability of a series of S-rich polyazamacrocyclic chelators with [Cu-64]Cu2+. Among the chelators considered, DO2A2S showed the best results. DO2A2S was labeled at high molar activities in mild reaction conditions, and its [Cu-64]Cu2+ complex exhibited excellent integrity in human serum.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sara Franchi, Valerio Di Marco, Marianna Tosato
Summary: This review provides an overview of the latest research on chelating agents for bismuth radioisotopes, including their chemical properties, radiolabelling investigations, and clinical studies, aiming to guide the design of novel optimal platforms for chelating α-emitters.
NUCLEAR MEDICINE AND BIOLOGY
(2022)
Article
Chemistry, Inorganic & Nuclear
Matteo Bevilacqua, Valerio Giuso, Marzio Rancan, Lidia Armelao, Claudia Graiff, Walter Baratta, Valerio Di Marco, Andrea Biffis
Summary: A series of protic N-heterocyclic carbene ligand precursors based on theophylline or adenine has been prepared and investigated for their reactivity and coordination chemistry towards iridium(III) centers. The formation of complexes appears to be highly influenced by the structure of the proligands. Notably, a particularly stable complex has been formed, allowing for fully reversible protonation/deprotonation of the coordinated NHC moiety. The acidity constant of the protonated complex was subsequently determined.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Andrea Romano, Luca Cappellin, Sara Bogialli, Paolo Pastore, Luciano Navarini, Franco Biasioli
Summary: This study presents the in vitro and in vivo aroma release analysis of three espresso coffees using PTR-ToF-MS headspace and nosespace analysis. The study found that the roasting degree and varietal compounds were important factors in coffee discrimination. Despite the relatively low number of peaks detected in nosespace, coffee discrimination was still possible. There were significant qualitative and quantitative differences between headspace and nosespace profiles.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Multidisciplinary
Parmissa Randhawa, K. Lexi Gower-Fry, Cailum M. K. Stienstra, Marianna Tosato, Shaohuang Chen, Yang Gao, Anthony W. McDonagh, Valerio Di Marco, Valery Radchenko, Georg Schreckenbach, Caterina F. Ramogida
Summary: This study reports a series of sulfur-rich chelators capable of stably coordinating Hg-197m/g to a tumor-targeting vector. The ability of these ligands to effectively coordinate Hg2+ was demonstrated through theoretical calculations and experimental studies, including NMR and mass spectrometry. Radiolabeling and in vitro stability assays further confirmed the potential application of these ligands. The development of stable ligands for Hg-197m/g reported in this study lays the foundation for their personalized use in in vivo imaging and therapy.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Inorganic & Nuclear
Marianna Tosato, Sara Franchi, Abdirisak Ahmed Isse, Alessandro Del Vecchio, Giordano Zanoni, Andre Alker, Mattia Asti, Thomas Gyr, Valerio Di Marco, Helmut Maecke
Summary: To prevent the reduction of Cu2+ to Cu+ in vivo, researchers have developed a new type of complex that can better stabilize both oxidation states of copper ions by using a smaller macrocyclic backbone. This new complex also showed higher stability in human serum compared to previous complexes.
INORGANIC CHEMISTRY
(2023)
Review
Chemistry, Medicinal
Sara Franchi, Mattia Asti, Valerio Di Marco, Marianna Tosato
Summary: This article provides a comprehensive overview of the current role of radium radioisotopes in nuclear medicine, with a focus on Ra-223. It critically examines the efforts made so far to incorporate Ra-223 into cancer-targeting drugs and highlights the chemical aspects of providing molecular scaffolds for the bifunctional chelator approach.
EJNMMI RADIOPHARMACY AND CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Marianna Tosato, Matteo Pelosato, Sara Franchi, Abdirisak Ahmed Isse, Nora Veronica May, Giordano Zanoni, Fabrizio Mancin, Paolo Pastore, Denis Badocco, Mattia Asti, Valerio Di Marco
Summary: This study synthesized three novel polyazamacrocyclic ligands as potential chelators for medical copper radioisotopes, and investigated their coordination properties with copper in aqueous solution. It was found that TRI4S and TE4S can stabilize both copper oxidation states, making them promising candidates for application in nuclear medicine.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Analytical
Chiara Giorio, Sara D'Aronco, Valerio Di Marco, Denis Badocco, Francesco Battaglia, Lidia Solda, Paolo Pastore, Andrea Tapparo
Summary: Metals in atmospheric aerosols have impacts on health and the environment, which depend on their solubility, dissolution kinetics, and chemical form. This study investigates the impact of fog processing on the solubility and dissolution kinetics of metals in PM2.5 samples collected in an urban background site. The study finds that the solubility of certain metals is higher in samples collected during foggy days compared to dry conditions.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2022)