Article
Transplantation
Takayuki Hamano, Takahiro Imaizumi, Takeshi Hasegawa, Naohiko Fujii, Hirotaka Komaba, Masahiko Ando, Masaomi Nangaku, Kosaku Nitta, Hideki Hirakata, Yoshitaka Isaka, Takashi Wada, Shoichi Maruyama, Masafumi Fukagawa
Summary: The CGA classification is more valuable than the GA classification in predicting kidney disease outcomes, and incorporating a prior biopsy-proven diagnosis significantly improves the accuracy of outcome prediction.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Biochemistry & Molecular Biology
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Eun Mi Yang, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Kook-Hwan Oh, Ji Yong Jung, Young Youl Hyun, Soo Wan Kim
Summary: The study investigated the association of urinary angiotensinogen (UAGT) with renal outcomes in patients with non-dialysis chronic kidney disease (CKD). The results showed that high UAGT level is associated with adverse renal outcomes, which is influenced by certain clinical contexts. Further studies are needed to validate the predictive role of UAGT as a biomarker for renal outcomes in CKD.
Article
Urology & Nephrology
Katherine R. Tuttle, Peter Rossing, Sibylle J. Hauske, Lisa Cronin, Joanna Hussain, Dick de Zeeuw, Hiddo J. L. Heerspink
Summary: This study aimed to evaluate the efficacy and safety of BI 690517 and determine if it has an additive kidney protection effect in CKD patients already treated with a renin-angiotensin system inhibitor. The results will inform dose selection for further clinical development.
AMERICAN JOURNAL OF NEPHROLOGY
(2023)
Article
Substance Abuse
Sangmi Lee, Shinchan Kang, Young Su Joo, Changhyun Lee, Ki Heon Nam, Hae-Ryong Yun, Jung Tak Park, Tae Ik Chang, Tae-Hyun Yoo, Soo Wan Kim, Kook-Hwan Oh, Yeong Hoon Kim, Sue K. Park, Shin-Wook Kang, Kyu Hun Choi, Curie Ahn, Seung Hyeok Han
Summary: The study found a significant association between smoking and worsening kidney function in CKD patients, with higher pack-years of smoking correlating with higher risk of adverse kidney outcomes. Quitting smoking was shown to potentially delay CKD progression, suggesting it is a modifiable factor in managing the disease.
NICOTINE & TOBACCO RESEARCH
(2021)
Article
Medicine, General & Internal
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Kook-Hwan Oh, Joongyub Lee, Yun Kyu Oh, Ji Yong Jung, Seong Kwon Ma, Soo Wan Kim
Summary: This study found that abdominal aortic calcification score (AACS) is associated with the risk of cardiovascular events in patients with pre-dialysis chronic kidney disease (CKD). A simple radiographic examination of the lateral abdomen can help stratify cardiovascular risk in this population.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Anastasia Poznyak, Nikolay K. Sadykhov, Andrey G. Kartuesov, Evgeny E. Borisov, Vasily N. Sukhorukov, Alexander N. Orekhov
Summary: Atherosclerosis is the leading cause of cardiovascular disease worldwide, and it shares several risk factors with chronic kidney disease. Patients with chronic kidney disease are more susceptible to cardiovascular problems.
Article
Medicine, General & Internal
Na Ri Kang, Yo Han Ahn, Eujin Park, Keum Hwa Lee, Hee Sun Baek, Seong Heon Kim, Heeyeon Cho, Min Hyun Cho, Jae Il Shin, Joo Hoon Lee, Hae Il Cheong, Hee Gyung Kang, Young Seo Park, Il-Soo Ha, Duk-Soo Moon, Kyoung Hee Han
Summary: This study investigated the intelligence levels and risk factors for low intelligence in children and adolescents with CKD, finding that participants with short stature, failure to thrive, more severe CKD stage, longer duration of CKD, and those who were Medicare or Medicaid beneficiaries had significantly lower intelligence levels. The association between intelligence and longer duration of CKD and growth failure remained significant after controlling for demographic and clinical variables, highlighting the importance of early interventions such as kidney transplantation.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Transplantation
Minjung Kang, Eunjeong Kang, Hyunjin Ryu, Yeji Hong, Seung Seok Han, Sue K. Park, Young Youl Hyun, Su Ah Sung, Soo Wan Kim, Tae-Hyun Yoo, Jayoun Kim, Curie Ahn, Kook-Hwan Oh
Summary: The study found that high salt intake was associated with an increased risk of CKD progression, particularly in women, patients under 60 years of age, those with uncontrolled hypertension, and individuals with obesity.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Nutrition & Dietetics
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Kook-Hwan Oh, Seung Hyeok Han, Soo Wan Kim
Summary: This study aimed to investigate the association between serum non-HDL-C levels and cardiovascular outcomes in non-dialysis chronic kidney disease patients. The study found that high serum non-HDL-C levels were associated with an increased risk of adverse cardiovascular outcomes, and this association was not affected by clinical factors such as age, gender, body mass index, estimated glomerular filtration rate, and albuminuria.
Article
Medicine, General & Internal
Cheol Ho Park, Hyung Woo Kim, Jung Tak Park, Tae Ik Chang, Tae-Hyun Yoo, Sue Kyung Park, Yaeni Kim, Ji Yong Jung, Jong Cheol Jeong, Kook-Hwan Oh, Shin-Wook Kang, Seung Hyeok Han
Summary: The 2021 KDIGO guideline recommends a target systolic blood pressure of <120 mmHg for managing hypertension in chronic kidney disease. It is uncertain whether implementing this target can improve kidney outcomes.
JOURNAL OF INTERNAL MEDICINE
(2023)
Article
Nutrition & Dietetics
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Kook-Hwan Oh, Young Youl Hyun, Suah Sung, Soo Wan Kim
Summary: The study reveals that both low and high serum nHDL levels are associated with increased risk of CKD progression in non-dialysis CKD patients.
Article
Cardiac & Cardiovascular Systems
Eunjeong Kang, Sung Woo Lee, Hyunjin Ryu, Minjung Kang, Seonmi Kim, Sue K. Park, Ji Yong Jung, Kyu-Beck Lee, Seung Hyeok Han, Curie Ahn, Kook-Hwan Oh
Summary: This study found that diastolic heart dysfunction is associated with the progression of chronic kidney disease, suggesting it as a novel risk factor.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Nutrition & Dietetics
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Kook-Hwan Oh, Young Youl Hyun, Suah Sung, Soo Wan Kim
Summary: The relationship between 24-h urinary phosphorus excretion (24 h UPE) and cardiovascular disease in pre-dialysis CKD patients is not well-studied. This study found that low 24 h UPE is associated with adverse cardiovascular outcomes in CKD patients, indicating that it should not be relied upon as a marker for dietary phosphorus restriction.
Article
Medicine, General & Internal
Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Eun Mi Yang, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Kook-Hwan Oh, Young Youl Hyun, Suah Sung, Soo Wan Kim
Summary: This study indicates that there is a clear association between low BMD and all-cause mortality in patients with nondialysis CKD. Osteoporosis is significantly associated with an increased risk of all-cause mortality, while osteopenia does not have a significant association. This suggests that the routine measurement of BMD may have additional benefits beyond predicting fracture risk in this population.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Transplantation
Maarten W. Taal, Bethany Lucas, Paul Roderick, Paul Cockwell, David C. Wheeler, Moin A. Saleem, Simon D. S. Fraser, Rosamonde E. Banks, Tim Johnson, Lorna J. Hale, Uwe Andag, Philipp Skroblin, Michaela Bayerlova, Robert Unwin, Nicolas Vuilleumier, Rodolphe Dusaulcy, Fiona Robertson, Elizabeth Colby, David Pitcher, Fiona Braddon, Melissa Benavente, Elaine Davies, Michael Nation, Philip A. Kalra
Summary: The NURTuRE-CKD cohort is a prospective study that aims to investigate risk factors for adverse outcomes in patients with chronic kidney disease (CKD). The study found that a majority of participants were in high-risk CKD categories, with the primary renal diagnosis being unknown cause. Older participants with lower estimated glomerular filtration rate had higher blood pressure and were less likely to be treated with renin-angiotensin system inhibitors, but were more likely to receive a statin.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Pediatrics
Jae Hong Choi, Young Mi Yoon, Yoon-Joo Kim, Kyoung Hee Han
Summary: The objective of this study was to assess the role of 16S ribosomal RNA analysis in microbial identification in febrile infants diagnosed with urinary tract infection (UTI) and compare it with conventional culture results. The study found that 16S rRNA analysis showed a certain level of accuracy in identifying uropathogens, and could be used in combination with conventional culture methods to manage febrile UTI in infants.
INDIAN JOURNAL OF PEDIATRICS
(2023)
Article
Clinical Neurology
Jae Won Oh, Sun Mi Kim, Deokjong Lee, Dong Keon Yon, Seung Won Lee, Lee Smith, Karel Kostev, Ai Koyanagi, Marco Solmi, Andre F. Carvalho, Jae Il Shin, Nak-Hoon Son, San Lee
Summary: This study utilized datasets from Brazil, China, Europe, Korea, the UK, and the US to investigate the association between handgrip strength and depression in middle and older aged adults. The results showed that lower handgrip strength was associated with an increased likelihood of depression. Early assessment of handgrip strength may help identify individuals at risk for depression among this population.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Public, Environmental & Occupational Health
Jong Mi Park, Wongi Woo, Sang Chul Lee, Seoyeon Park, Dong Keon Yon, Seung Won Lee, Lee Smith, Ai Koyanagi, Jae Il Shin, Yong Wook Kim
Summary: This comprehensive review aims to determine the prevalence of various neurological disorders in COVID-19 and found that the prevalence and mortality risk may increase in some neurological diseases during the COVID-19 pandemic. Future studies should investigate the underlying mechanisms, identify patient characteristics associated with neurological diseases, and consider global patient management.
Article
Pediatrics
Hee Sun Baek, Min Ji Park, Ji Yeon Song, Seong Heon Kim, Hee Gyung Kang, Yo Han Ahn, Kyoung Hee Han, Heeyeon Cho, Keum Hwa Lee, Jae Il Shin, Young Seo Park, Joo Hoon Lee, Eujin Park, Eun Mi Yang, Min Hyun Cho
Summary: This study aimed to assess the association between changes in serum total cholesterol levels and the progression of CKD in children. The results showed that very high serum total cholesterol is a significant risk factor for the progression of CKD in children.
PEDIATRIC NEPHROLOGY
(2023)
Review
Virology
Hyunju Yon, Hyoin Shin, Jae Il Shin, Jung U. Shin, Youn Ho Shin, Jinseok Lee, Sang Youl Rhee, Ai Koyanagi, Louis Jacob, Lee Smith, Seung Won Lee, Masoud Rahmati, Suhana Ahmad, Wonyoung Cho, Dong Keon Yon
Summary: A systematic review and meta-analysis of monkeypox infection revealed common clinical features including rash, chills, fever, and lymphadenopathy. This study provides important data on the pathophysiology and epidemiology of monkeypox infections.
REVIEWS IN MEDICAL VIROLOGY
(2023)
Article
Oncology
Louis Jacob, Ai Koyanagi, Josep Maria Haro, Jae Il Shin, Lee Smith, Niklas Gremke, Matthias Kalder, Karel Kostev
Summary: This retrospective cohort study found no significant association between breast cancer and adhesive capsulitis in adults from Germany.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Multidisciplinary Sciences
Soo-Young Yoon, Hye Won Park, Hyeon Jin Kim, Andreas Kronbichler, Ai Koyanagi, Lee Smith, Jae Il Shin, Sang Youl Rhee, Seung Won Lee, Jin Sug Kim, Hyeon Seok Hwang, Dong Keon Yon, Kyunghwan Jeong
Summary: The prevalence of chronic kidney disease (CKD) decreased during the COVID-19 pandemic, particularly in 2020. This study provides the first large-scale investigation into the longitudinal prevalence of CKD from 2007 to 2020, and further research is needed to understand the reasons for this decline and develop healthcare policy strategies for CKD prevention and management.
SCIENTIFIC REPORTS
(2023)
Article
Nutrition & Dietetics
Lee Smith, Guillermo F. Lopez F. Sanchez, Mark A. Tully, Louis Jacob, Karel Kostev, Hans Oh, Laurie Butler, Yvonne Barnett, Jae Il Shin, Ai Koyanagi
Summary: This study examined the trends of food insecurity among school-going adolescents aged 12-15 years from 31 countries. The prevalence of food insecurity varied in different countries, with both increasing and decreasing trends observed. It is crucial to take global action to address this issue and achieve the Sustainable Development Goal 2.
Article
Geriatrics & Gerontology
Lee Smith, Guillermo Lopez F. Sanchez, Jae Il Shin, Pinar Soysal, Damiano Pizzol, Yvonne Barnett, Karel Kostev, Louis Jacob, Nicola Veronese, Laurie Butler, Helen Odell-Miller, Jodie Bloska, Benjamin R. Underwood, Ai Koyanagi
Summary: This study investigated the association between pain and mild cognitive impairment (MCI) in low- and middle-income countries (LMICs). The results showed a dose-dependent association between pain and MCI, with sleep problems and mobility limitations identified as potential mediators.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Review
Psychiatry
Heeyeon Kim, Jae Han Kim, Junghwan Kim, Jong Yeob Kim, Samuele Cortese, Lee Smith, Ai Koyanagi, Joaquim Radua, Paolo Fusar-Poli, Andre F. Carvalho, Gonzalo Salazar de Pablo, Jae Il Shin, Keun-Ah Cheon, Marco Solmi
Summary: The study aimed to summarize the evidence on sleep alterations in medication-naive children and adolescents with autism spectrum disorder (ASD). Sixteen observational studies were included, with a total of 981 ASD patients and 1220 typically developing individuals. The results showed that medication-naive ASD patients had significantly poorer sleep quality compared to the typically developing group, with longer sleep latency, reduced sleep efficiency, difficulties in initiating and maintaining sleep, and sleep hyperhidrosis.
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2023)
Meeting Abstract
Pediatrics
Jihyun Kim, Yo Han Ahn, Jeesu Min, Kyung Hee Han, Seong Heon Kim, Hee Yeon Cho, Min Hyun Cho, Jae Il Shin, Joo Hoon Lee, Hee Gyung Kang, Hae Il Cheong
PEDIATRIC NEPHROLOGY
(2023)
Meeting Abstract
Respiratory System
Wongi Woo, Vincent Kipkorir, Du-young Kang, Adina Marza, Alessandro Belletti, Shadi Hamouri, Abdulqadir Nashwan, Giuseppe Fiorentino, Muhammad Mohsin Khan, Ayat Alhakeem, Sarya Swed, Moezedin Javad Rafiee, Wooshik Kim, Duk Hwan Moon, Jae Il Shin, Sungsoo Lee
Article
Pharmacology & Pharmacy
C. Y. Ban, H. Shin, S. Eum, H. Yon, S. W. Lee, Y. S. Choi, Y. H. Shin, J. U. Shin, A. Koyanagi, L. Jacob, L. Smith, C. Min, A. O. Yeniova, S. Y. Kim, J. Lee, S. -G Yeo, R. Kwon, M. J. Koo, G. Fond, L. Boyer, K. P. Acharya, S. Kim, H. G. Woo, S. Park, J. I. Shin, S. Y. Rhee, D. K. Yon
Summary: This study aimed to analyze trends in mean BMI, obesity, and overweight among Korean adolescents, including the mid-stage of the COVID-19 pandemic. The findings showed a gradual increase in BMI and prevalence of obesity and overweight over the past 17 years, but the increase during the pandemic was less significant than before. These results emphasize the importance of implementing practical prevention measures against youth obesity and overweight.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Pharmacology & Pharmacy
N. Kim, J. Y. Song, H. Yang, M. J. Kim, K. Lee, Y. H. Shin, S. Y. Rhee, J. Hwang, M. S. Kim, G. Fond, L. Boyer, S. Y. Kim, J. I. Shin, S. W. Lee, D. K. Yon
Summary: It is necessary to examine the trend in suicide-related behaviors among adolescents in South Korea over a longer period, including during COVID-19, as it is difficult to draw conclusions about the association between COVID-19 and a decrease in suicide attempts based on short-term comparisons. This study found that during the pandemic, the prevalence of sadness/despair and suicidal ideation and attempts among South Korean adolescents was higher than expected, indicating the need for further research on the impact of the pandemic on mental health and the establishment of prevention strategies for suicide ideation and attempts.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Medicine, General & Internal
Muhammad Ajmal, Hafsah Muhammad, Muhammad Nasir, Muhammad Shoaib, Salman Akbar Malik, Irfan Ullah
Summary: This study investigated a Pakistani family with hereditary multiple exostoses (HME) and identified a heterozygous deletion (c.247Cdel) in exon 1 of the EXT1 gene, resulting in a frameshift mutation (p.R83GfsX52) and an alternative open reading frame (ORF3). The linkage analysis revealed that the HME family is linked to the EXT1 locus 8q24.1. The findings suggest that haploinsufficiency and the predicted ORF3 protein may play important roles in the pathogenesis of HME.
MEDICINA-LITHUANIA
(2023)
