Chitosan Oligosaccharides Alleviate H2O2-stimulated Granulosa Cell Damage via HIF-1α Signaling Pathway

The role of Chito-oligosaccharide in regulating ovarian germ stem cells function and restoring ovarian function in chemotherapy mice

(2021) Yaoqi Huang et al.   Reproductive Biology and Endocrinology

Hypoxia/HIF Modulates Immune Responses

(2021) Yuling Chen et al.   Biomedicines

Melatonin Represses Mitophagy to Protect Mouse Granulosa Cells from Oxidative Damage

(2021) Yi Jiang et al.   Biomolecules

Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

(2020) Si Wang et al.   CELL

Silencing of soluble epoxide hydrolase 2 gene reduces H2O2-induced oxidative damage in rat intestinal epithelial IEC-6 cells via activating PI3K/Akt/GSK3β signaling pathway

(2020) Jun Li et al.   CYTOTECHNOLOGY

Treatment with 7% and 10% CO2 enhanced expression of IL-1β, TNF-α, and IL-6 in hypoxic cultures of human whole blood

(2020) Hongguang Ding et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Abnormalities of hydrogen sulfide and glutathione pathways in mitochondrial dysfunction

(2020) Catarina M Quinzii et al.   Journal of Advanced Research

Psychological aspects of infertility. A systematic review

(2020) Filip Szkodziak et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Intermittent hypobaric hypoxia causes deleterious effects on the reproductive system in female rats

(2020) Weili Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

The Role of HIF in Immunity and Inflammation

(2020) Anne F. McGettrick et al.   Cell Metabolism

Towards a comprehensive view of 8-oxo-7,8-dihydro-2’-deoxyguanosine: Highlighting the intertwined roles of DNA damage and epigenetics in genomic instability

(2020) Francesca Gorini et al.   DNA REPAIR

Resveratrol attenuates hydrogen peroxide-induced aging through upregulation of autophagy in human umbilical vein endothelial cells

(2019) Ligen Du et al.   Drug Design Development and Therapy

Resveratrol alleviates chemotherapy-induced oogonial stem cell apoptosis and ovarian aging in mice

(2019) Meng Wu et al.   Aging-US

Chitosan oligosaccharide (COS): An overview

(2019) Muhammad Naveed et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Biological Effects and Applications of Chitosan and Chito-Oligosaccharides

(2019) Guiping Guan et al.   Frontiers in Physiology

Hypoxia and aging

(2019) Eui-Ju Yeo   EXPERIMENTAL AND MOLECULAR MEDICINE

Modulating effects of preconditioning exercise in the expression of ET-1 and BNP via HIF-1α in ischemically injured brain

(2019) Huijie Wang et al.   METABOLIC BRAIN DISEASE

TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019

(2019) Dewidar et al.   Cells

Aging, inflammation and the environment

(2018) Arsun Bektas et al.   EXPERIMENTAL GERONTOLOGY

Hypoxia, oxidative stress and inflammation

(2018) Trudy McGarry et al.   FREE RADICAL BIOLOGY AND MEDICINE

Curcumin exerts a protective effect against premature ovarian failure in mice

(2018) Zhengjie Yan et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Melatonin protects mouse granulosa cells against oxidative damage by inhibiting FOXO1-mediated autophagy: Implication of an antioxidation-independent mechanism

(2018) Ming Shen et al.   Redox Biology

The senescent cell epigenome

(2018) Na Yang et al.   Aging-US

Intracellular calcium and NF-kB regulate hypoxia-induced leptin, VEGF, IL-6 and adiponectin secretion in human adipocytes

(2018) Azizah Al-Anazi et al.   LIFE SCIENCES

Exosome-based immunomodulation during aging: A nano-perspective on inflamm-aging

(2017) Francesco Prattichizzo et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The emerging role of epigenetic modifiers in repair of DNA damage associated with chronic inflammatory diseases

(2017) Ning Ding et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Chitosan oligosaccharide: Biological activities and potential therapeutic applications

(2017) Chatchai Muanprasat et al.   PHARMACOLOGY & THERAPEUTICS

Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma

(2017) Hongyan Yang et al.   Oncotarget

Cellular and exosome mediated molecular defense mechanism in bovine granulosa cells exposed to oxidative stress

(2017) Mohammed Saeed-Zidane et al.   PLoS One

Moderate increase of reactive oxygen species triggers meiotic resumption in rat follicular oocytes

(2016) Meenakshi Tiwari et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence

(2016) E. Molinari et al.   MOLECULAR HUMAN REPRODUCTION

NF-κB and HIF crosstalk in immune responses

(2015) Laura D'Ignazio et al.   FEBS Journal

The cross-talk between NF-κB and HIF-1: further evidence for a significant liaison: Figure 1

(2015) Agnes Görlach et al.   BIOCHEMICAL JOURNAL

Risk factors for miscarriage from a prevention perspective: a nationwide follow-up study

(2014) S Feodor Nilsson et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

Vascular Endothelial Growth Factor Signaling in Hypoxia and Inflammation

(2014) S. Ramakrishnan et al.   Journal of Neuroimmune Pharmacology

Grape Seed Proanthocyanidin Extract Protects Against Carrageenan-Induced Lung Inflammation in Mice Through Reduction of Pro-inflammatory Markers and Chemokine Expressions

(2013) Sheikh Fayaz Ahmad et al.   INFLAMMATION

Faulty DNA Repair Linked to Ovarian Aging in Mice and Humans

(2013) J. Couzin-Frankel   SCIENCE

Effects of antioxidants and MAPK inhibitors on cell death and reactive oxygen species levels in H2O2-treated human pulmonary fibroblasts

(2013) WOO HYUN PARK   Oncology Letters

Superoxide Dismutase in Redox Biology: The Roles of Superoxide and Hydrogen Peroxide

(2012) Garry R. Buettner   Anti-Cancer Agents in Medicinal Chemistry

Molecular control of oogenesis

(2012) Flor Sánchez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Chemokine C-C motif receptor 5 and C-C motif ligand 5 promote cancer cell migration under hypoxia

(2012) Sensen Lin et al.   CANCER SCIENCE

Follicular Growth and Atresia in Mammalian Ovaries: Regulation by Survival and Death of Granulosa Cells

(2012) Fuko MATSUDA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Involvement of Hypoxia-Inducible Factor-1 in the Inflammatory Responses of Human LAD2 Mast Cells and Basophils

(2012) Vadim V. Sumbayev et al.   PLoS One

Oxidative Damage Increases and Antioxidant Gene Expression Decreases with Aging in the Mouse Ovary

(2010) J. Lim et al.   BIOLOGY OF REPRODUCTION

Human cumulus cells as biomarkers for embryo and pregnancy outcomes

(2010) S. Assou et al.   MOLECULAR HUMAN REPRODUCTION

Effect of arachidonic acid on hypoxia-induced IL-6 production in mouse ES cells: Involvement of MAPKs, NF-κB, and HIF-1α

(2009) Sang Hun Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Angiogenesis and vascular function in the ovary

(2009) R S Robinson et al.   REPRODUCTION

Redox Considerations in Female Reproductive Function and Assisted Reproduction: From Molecular Mechanisms to Health Implications

(2008) Ashok Agarwal et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive oxygen species and oocyte aging: Role of superoxide, hydrogen peroxide, and hypochlorous acid

(2007) Anuradha P. Goud et al.   FREE RADICAL BIOLOGY AND MEDICINE