NaV1.1 haploinsufficiency impairs glutamatergic and GABAergic neuron function in the thalamus

Positive AMPA receptor modulation in the treatment of neuropsychiatric disorders: A long and winding road

(2021) Bashkim Kadriu et al.   DRUG DISCOVERY TODAY

PTC-174, a positive allosteric modulator of NMDA receptors containing GluN2C or GluN2D subunits

(2020) Feng Yi et al.   NEUROPHARMACOLOGY

Two dynamically distinct circuits drive inhibition in the sensory thalamus

(2020) Rosa I. Martinez-Garcia et al.   NATURE

Distinct subnetworks of the thalamic reticular nucleus

(2020) Yinqing Li et al.   NATURE

Developmental alterations in firing properties of hippocampal CA1 inhibitory and excitatory neurons in a mouse model of Dravet syndrome

(2020) Yael Almog et al.   NEUROBIOLOGY OF DISEASE

Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet Syndrome

(2019) Stefanie Ritter-Makinson et al.   Cell Reports

Modulation of Burst Firing of Neurons in Nucleus Reticularis of the Thalamus by GluN2C-Containing NMDA Receptors

(2019) Jinxu Liu et al.   MOLECULAR PHARMACOLOGY

Sleep Spindles: Mechanisms and Functions

(2019) Laura M. J. Fernandez et al.   PHYSIOLOGICAL REVIEWS

Cortical drive and thalamic feed-forward inhibition control thalamic output synchrony during absence seizures

(2018) Cian McCafferty et al.   NATURE NEUROSCIENCE

A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome

(2018) Morgana Favero et al.   JOURNAL OF NEUROSCIENCE

The Cognitive Thalamus as a Gateway to Mental Representations

(2018) Mathieu Wolff et al.   JOURNAL OF NEUROSCIENCE

Group II Metabotropic Glutamate Receptors: Role in Pain Mechanisms and Pain Modulation

(2018) Mariacristina Mazzitelli et al.   Frontiers in Molecular Neuroscience

Dravet syndrome: Characteristics, comorbidities, and caregiver concerns

(2017) Nicole Villas et al.   EPILEPSY & BEHAVIOR

From genotype to phenotype in Dravet disease

(2017) Svetlana Gataullina et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Distinct Thalamic Reticular Cell Types Differentially Modulate Normal and Pathological Cortical Rhythms

(2017) Alexandra Clemente-Perez et al.   Cell Reports

Screening for AMPA receptor auxiliary subunit specific modulators

(2017) Caleigh M. Azumaya et al.   PLoS One

Two classes of excitatory synaptic responses in rat thalamic reticular neurons

(2016) Charlotte Deleuze et al.   JOURNAL OF NEUROPHYSIOLOGY

Tapping the Brakes: Cellular and Synaptic Mechanisms that Regulate Thalamic Oscillations

(2016) P. Michelle Fogerson et al.   NEURON

Cognitive Deficits Associated with Nav1.1 Alterations: Involvement of Neuronal Firing Dynamics and Oscillations

(2016) Alex C. Bender et al.   PLoS One

Improved Methods for Fluorescence Microscopy Detection of Macromolecules at the Axon Initial Segment

(2016) Musaad A. Alshammari et al.   Frontiers in Cellular Neuroscience

Dissecting the phenotypes of Dravet syndrome by gene deletion

(2015) Moran Rubinstein et al.   BRAIN

Autism and behavior in adult patients with Dravet syndrome (DS)

(2015) J.J.L. Berkvens et al.   EPILEPSY & BEHAVIOR

Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome

(2015) Moran Rubinstein et al.   NEUROBIOLOGY OF DISEASE

Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome

(2015) Franck Kalume et al.   NEUROBIOLOGY OF DISEASE

A Corticothalamic Switch: Controlling the Thalamus with Dynamic Synapses

(2015) Shane R. Crandall et al.   NEURON

Long-term course of Dravet syndrome: A study from an epilepsy center in Japan

(2014) Rumiko Takayama et al.   EPILEPSIA

Impaired Action Potential Initiation in GABAergic Interneurons Causes Hyperexcitable Networks in an Epileptic Mouse Model Carrying a Human NaV1.1 Mutation

(2014) U. B. S. Hedrich et al.   JOURNAL OF NEUROSCIENCE

Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome

(2014) C. Tai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variability of EEG-fMRI findings in patients withSCN1A-positive Dravet syndrome

(2013) Jan Moehring et al.   EPILEPSIA

Altered sleep regulation in a mouse model ofSCN1A-derived genetic epilepsy with febrile seizures plus (GEFS+)

(2013) Ligia A. Papale et al.   EPILEPSIA

Mapping genetic modifiers of survival in a mouse model of Dravet syndrome

(2013) A. R. Miller et al.   GENES BRAIN AND BEHAVIOR

Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome

(2013) Ikuo Ogiwara et al.   HUMAN MOLECULAR GENETICS

Chronic Pain: Lost Inhibition?

(2013) L. A. Henderson et al.   JOURNAL OF NEUROSCIENCE

Focal Scn1a knockdown induces cognitive impairment without seizures

(2013) Alex C. Bender et al.   NEUROBIOLOGY OF DISEASE

T-Type Ca2+ Channels in Normal and Abnormal Brain Functions

(2013) Eunji Cheong et al.   PHYSIOLOGICAL REVIEWS

Progressive Gait Deterioration in Adolescents With Dravet Syndrome

(2012) Jill M. Rodda et al.   ARCHIVES OF NEUROLOGY

Therapeutic Potential of Metabotropic Glutamate Receptor Modulators

(2012) N. Hovelso et al.   Current Neuropharmacology

Autistic-like behaviour in Scn1a +/− mice and rescue by enhanced GABA-mediated neurotransmission

(2012) Sung Han et al.   NATURE

Dravet syndrome as epileptic encephalopathy: evidence from long-term course and neuropathology

(2011) C. B. Catarino et al.   BRAIN

Current therapeutic procedures in Dravet syndrome

(2011) CATHERINE CHIRON   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Cognitive development in children with Dravet syndrome

(2011) Francesca Ragona   EPILEPSIA

The core Dravet syndrome phenotype

(2011) Charlotte Dravet   EPILEPSIA

A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors

(2010) Praseeda Mullasseril et al.   Nature Communications

Neurons that Fire Together Also Conspire Together: Is Normal Sleep Circuitry Hijacked to Generate Epilepsy?

(2009) Mark P. Beenhakker et al.   NEURON

Vesicular glutamate transporters define two sets of glutamatergic afferents to the somatosensory thalamus and two thalamocortical projections in the mouse

(2008) Alessandro Graziano et al.   JOURNAL OF COMPARATIVE NEUROLOGY