Journal
NATURE REVIEWS CLINICAL ONCOLOGY
Volume 19, Issue 8, Pages 495-496Publisher
NATURE PORTFOLIO
DOI: 10.1038/s41571-022-00634-0
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- Melanoma Moon Shot
- MD Anderson Platform for Innovative Microbiome and Translational Research (PRIME-TR)
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Two recent large-cohort studies have shown the potential predictive capability of gut microbiota for immune-checkpoint inhibitor response and toxicities in patients with melanoma. However, further investigations are needed to understand the mechanistic underpinnings of this complex relationship and how it can be utilized for personalized cancer care.
Two recent large-cohort studies reinforce the potential predictive capability of gut microbiota for immune-checkpoint inhibitor response and toxicities in patients with melanoma. However, additional investigations are required to understand the mechanistic underpinnings of this complex multifaceted relationship, and how it can be exploited for personalized cancer care.
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