Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

Quarantine and testing strategies in contact tracing for SARS-CoV-2: a modelling study

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Asymptomatic SARS-CoV-2 Carriers: A Systematic Review and Meta-Analysis

(2021) Gopiram Syangtan et al.   Frontiers in Public Health

Dynamics of SARS-CoV-2 shedding in the respiratory tract depends on the severity of disease in COVID-19 patients

(2021) Dieter Munker et al.   EUROPEAN RESPIRATORY JOURNAL

Transmission of COVID-19 in 282 clusters in Catalonia, Spain: a cohort study

(2021) Michael Marks et al.   LANCET INFECTIOUS DISEASES

Duration of Culturable SARS-CoV-2 in Hospitalized Patients with Covid-19

(2021) Min-Chul Kim et al.   NEW ENGLAND JOURNAL OF MEDICINE

Innate-like Gene Expression of Lung-resident Memory CD8+ T-cells During Experimental Human Influenza: A Clinical Study

(2021) Suzanna Paterson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19

(2021) Andreas Barratt-Due et al.   ANNALS OF INTERNAL MEDICINE

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study

(2021) Thomas M Drake et al.   LANCET

SARS-CoV-2 Human Challenge Studies — Establishing the Model during an Evolving Pandemic

(2021) Garth Rapeport et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 Months

(2021) Stephen J. Thomas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters

(2021) Rana Abdelnabi et al.   EBioMedicine

Clinical Outcomes for Patients With Anosmia 1 Year After COVID-19 Diagnosis

(2021) Marion Renaud et al.   JAMA Network Open

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study

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Viral loads of Delta-variant SARS-CoV-2 breakthrough infections after vaccination and booster with BNT162b2

(2021) Matan Levine-Tiefenbrun et al.   NATURE MEDICINE

Early Remdesivir to Prevent Progression to Severe Covid-19 in Outpatients

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In vivo kinetics of SARS-CoV-2 infection and its relationship with a person’s infectiousness

(2021) Ruian Ke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus

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Recalibrating SARS-CoV-2 Antigen Rapid Lateral Flow Test Relative Sensitivity from Validation Studies to Absolute Sensitivity for Indicating Individuals Shedding Transmissible Virus

(2021) Irene Petersen et al.   Clinical Epidemiology

A Familial Cluster of Infection Associated With the 2019 Novel Coronavirus Indicating Possible Person-to-Person Transmission During the Incubation Period

(2020) Ping Yu et al.   JOURNAL OF INFECTIOUS DISEASES

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

(2020) Lirong Zou et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application

(2020) Stephen A. Lauer et al.   ANNALS OF INTERNAL MEDICINE

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

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Pathogenesis and transmission of SARS-CoV-2 in golden hamsters

(2020) Sin Fun Sia et al.   NATURE

Virological assessment of hospitalized patients with COVID-2019

(2020) Roman Wölfel et al.   NATURE

Temporal dynamics in viral shedding and transmissibility of COVID-19

(2020) Xi He et al.   NATURE MEDICINE

Remdesivir for the Treatment of Covid-19 — Preliminary Report

(2020) John H. Beigel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Exploring the acceptability of controlled human infection with SARSCoV2—a public consultation

(2020) D. Gbesemete et al.   BMC Medicine

SARS-CoV-2 viral load in the upper respiratory tract of children and adults with early acute COVID-19

(2020) Stéphanie Baggio et al.   CLINICAL INFECTIOUS DISEASES

Proportion of asymptomatic coronavirus disease 2019: A systematic review and meta‐analysis

(2020) Jingjing He et al.   JOURNAL OF MEDICAL VIROLOGY

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

(2020) Brandi N. Williamson et al.   NATURE

Accelerating Development of SARS-CoV-2 Vaccines — The Role for Controlled Human Infection Models

(2020) Meagan E. Deming et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates

(2020) Kizzmekia S. Corbett et al.   NEW ENGLAND JOURNAL OF MEDICINE

Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development

(2020) Masaki Imai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal transmission in an influenza A (H3N2) human challenge-transmission model within a controlled exposure environment

(2020) Jonathan S. Nguyen-Van-Tam et al.   PLoS Pathogens

SARS-CoV-2 controlled human infection models: Ethics, challenge agent production and regulatory issues

(2020) Marc Baay et al.   BIOLOGICALS

Viewpoint of a WHO Advisory Group Tasked to Consider Establishing a Closely-Monitored Challenge Model of COVID-19 in Healthy Volunteers

(2020) Myron M Levine et al.   CLINICAL INFECTIOUS DISEASES

SARS-CoV-2 detection, viral load and infectivity over the course of an infection

(2020) Kieran A. Walsh et al.   JOURNAL OF INFECTION

Anosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infection

(2020) Rafal Butowt et al.   NEUROSCIENTIST

Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection

(2020) Maximillian S. Habibi et al.   SCIENCE

RNAemia Corresponds to Disease Severity and Antibody Response in Hospitalized COVID-19 Patients

(2020) Kirsten Alexandra Eberhardt et al.   Viruses-Basel

Living risk prediction algorithm (QCOVID) for risk of hospital admission and mortality from coronavirus 19 in adults: national derivation and validation cohort study

(2020) Ash K Clift et al.   BMJ-British Medical Journal

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

(2020) Merryn Voysey et al.   LANCET

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

(2015) Agnieszka Jozwik et al.   Nature Communications

Comparing influenza and RSV viral and disease dynamics in experimentally infected adults predicts clinical effectiveness of RSV antivirals

(2013) Bindiya Bagga et al.   ANTIVIRAL THERAPY

Viral Load Drives Disease in Humans Experimentally Infected with Respiratory Syncytial Virus

(2010) John P. DeVincenzo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE