A non-canonical tricarboxylic acid cycle underlies cellular identity

A genome-wide atlas of co-essential modules assigns function to uncharacterized genes

(2021) Michael Wainberg et al.   NATURE GENETICS

SciPy 1.0: fundamental algorithms for scientific computing in Python

(2020) Pauli Virtanen et al.   NATURE METHODS

Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells

(2020) Xiphias Ge Zhu et al.   Cell Metabolism

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

(2020) Alba Luengo et al.   MOLECULAR CELL

IsoCor: isotope correction for high-resolution MS labeling experiments

(2019) Pierre Millard et al.   BIOINFORMATICS

Intracellular Ca2+ Homeostasis and Nuclear Export Mediate Exit from Naive Pluripotency

(2019) Matthew S. MacDougall et al.   Cell Stem Cell

Next-generation characterization of the Cancer Cell Line Encyclopedia

(2019) Mahmoud Ghandi et al.   NATURE

Mechanisms and Implications of Metabolic Heterogeneity in Cancer

(2019) Jiyeon Kim et al.   Cell Metabolism

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells

(2019) Pei-Hsuan Chen et al.   MOLECULAR CELL

OUP accepted manuscript

(2018)   BIOINFORMATICS

Aspartate is an endogenous metabolic limitation for tumour growth

(2018) Lucas B. Sullivan et al.   NATURE CELL BIOLOGY

Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies

(2018) Alexander Muir et al.   Disease Models & Mechanisms

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

(2017) Robin M Meyers et al.   NATURE GENETICS

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer

(2016) Shawn M. Davidson et al.   Cell Metabolism

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch

(2016) Steven Zhao et al.   Cell Reports

MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-κB

(2016) Jonathan Shintaku et al.   Cell Reports

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

(2015) Kıvanç Birsoy et al.   CELL

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

(2015) Lucas B. Sullivan et al.   CELL

Integrated, Step-Wise, Mass-Isotopomeric Flux Analysis of the TCA Cycle

(2015) Tiago C. Alves et al.   Cell Metabolism

Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells

(2015) Arieh Moussaieff et al.   Cell Metabolism

Inducible in vivo genome editing with CRISPR-Cas9

(2015) Lukas E Dow et al.   NATURE BIOTECHNOLOGY

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

(2014) Caroline A. Lewis et al.   MOLECULAR CELL

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

(2014) Bryce W. Carey et al.   NATURE

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Analysis of Tumor Metabolism Reveals Mitochondrial Glucose Oxidation in Genetically Diverse Human Glioblastomas in the Mouse Brain In Vivo

(2012) Isaac Marin-Valencia et al.   Cell Metabolism

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

(2011) Jason Wray et al.   NATURE CELL BIOLOGY