Microwave-Assisted Synthesis, Biological Activity Evaluation, Molecular Docking, and ADMET Studies of Some Novel Pyrrolo [2,3-b] Pyrrole Derivatives

Development of New Thiazole Complexes as Powerful Catalysts for Synthesis of Pyrazole-4-Carbonitrile Derivatives under Ultrasonic Irradiation Condition Supported by DFT Studies

(2021) Mahmoud Abd El Aleem Ali Ali El-Remaily et al.   ACS Omega

Optical characterization and effects of iodine vapor & gaseous HCl adsorption investigation of novel synthesized organic dye based on thieno[2,3-b]thiophene

(2021) E. Kh. Shokr et al.   OPTIK

New nicotinic acid-based 3,5-diphenylpyrazoles: design, synthesis and antihyperlipidemic activity with potential NPC1L1 inhibitory activity

(2020) Mai E. Shoman et al.   MOLECULAR DIVERSITY

In Silico ADME/Tox Profiling of Natural Products: A Focus on BIOFACQUIM

(2020) Noemi Angeles Durán-Iturbide et al.   ACS Omega

Stereoselective synthesis of E, E / E, Z isomers based on 1-(4- iodophenyl)-2,5-divinyl-1H-pyrrole core skeleton: A configuration-controlled fluorescence characteristics and highly selective anti-cancer activity

(2020) Majeed Irfan et al.   DYES AND PIGMENTS

An In Silico Model for Predicting Drug-Induced Hepatotoxicity

(2019) Shuaibing He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules

(2019) Antoine Daina et al.   NUCLEIC ACIDS RESEARCH

Predicting Fraction Unbound in Human Plasma from Chemical Structure: Improved Accuracy in the Low Value Ranges

(2018) Reiko Watanabe et al.   MOLECULAR PHARMACEUTICS

Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study

(2018) Jim Luijten et al.   ATHEROSCLEROSIS

Virtual screening in drug-likeness and structure/activity relationship of pyridazine derivatives as Anti-Alzheimer drugs

(2018) Anfel Zerroug et al.   JOURNAL OF KING SAUD UNIVERSITY SCIENCE

Bean peptides have higher in silico binding affinities than ezetimibe for the N-terminal domain of cholesterol receptor Niemann-Pick C1 Like-1

(2017) Luis M. Real Hernandez et al.   PEPTIDES

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Anti-inflammatory activity effect of 2-substituted-1,4,5,6-tetrahydrocyclopenta[b]pyrrole on TPA-induced skin inflammation in mice

(2016) Xue-Tao Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Insecticidal effect of two novel pyrrole derivatives against two major stored product insect species

(2016) Maria C. Boukouvala et al.   CROP PROTECTION

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

(2015) Douglas E. V. Pires et al.   JOURNAL OF MEDICINAL CHEMISTRY

Assessment of conformational, spectral, antimicrobial activity, chemical reactivity and NLO application of Pyrrole-2,5-dicarboxaldehyde bis(oxaloyldihydrazone)

(2015) Poonam Rawat et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Design, synthesis and anti-mycobacterial activity of 1,2,3,5-tetrasubstituted pyrrolyl-N-acetic acid derivatives

(2014) Lakshmi Reddy Pagadala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport

(2011) Lin Jia et al.   Annual Review of Physiology

An efficient synthesis of highly functionalized novel chromeno[4,3-b]pyrroles and indolizino[6,7-b]indoles as potent antimicrobial and antioxidant agents

(2011) Natarajan Arumugam et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

N-Alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives with heterocyclic substitutions as potent and broad spectrum anticoccidial agents

(2008) Gui-Bai Liang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nicotinic acid: an old drug with a promising future

(2007) E T Bodor et al.   BRITISH JOURNAL OF PHARMACOLOGY