Coumarin-Palladium(II) Complex Acts as a Potent and Non-Toxic Anticancer Agent against Pancreatic Carcinoma Cells

SOX9 modulates cancer biomarker and cilia genes in pancreatic cancer

(2021) Hannah E Edelman et al.   HUMAN MOLECULAR GENETICS

Synthesis and Biological Screening of New 4-Hydroxycoumarin Derivatives and Their Palladium(II) Complexes

(2021) Edina H. Avdović et al.   Oxidative Medicine and Cellular Longevity

A Mini-Review: Recent Advances in Coumarin-Metal Complexes With Biological Properties

(2021) Łukasz Balewski et al.   Frontiers in Chemistry

Coumarins and Gastrointestinal Cancer: A New Therapeutic Option?

(2021) Zarrin Banikazemi et al.   Frontiers in Oncology

The tumour microenvironment in pancreatic cancer — clinical challenges and opportunities

(2020) Won Jin Ho et al.   Nature Reviews Clinical Oncology

Pancreatic cancer treatment: better, but a long way to go

(2020) Robert J. Torphy et al.   SURGERY TODAY

Synthesis, crystal structure, antiproliferative activity, DNA binding and density functional theory calculations of 3‐(pyridin‐2‐yl)‐8‐ tert ‐butylcoumarin and its copper(II) complex

(2020) Wen Lu et al.   APPLIED ORGANOMETALLIC CHEMISTRY

Pancreatic cancer

(2020) Jonathan D Mizrahi et al.   LANCET

Coumarins and Coumarin-Related Compounds in Pharmacotherapy of Cancer

(2020) Esra Küpeli Akkol et al.   Cancers

Anticancer Strategy Targeting Cell Death Regulators: Switching the Mechanism of Anticancer Floxuridine-Induced Cell Death from Necrosis to Apoptosis

(2020) Akira Sato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis

(2020) Garima Kaushik et al.   ONCOGENE

Design and synthesis of functionalized coumarins as potential anti-austerity agents that eliminates cancer cells' tolerance to nutrition starvation

(2019) Suresh Awale et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anticancer evaluation of ruthenium(III) complexes with N-donor ligands tethered to coumarin or uracil moieties

(2019) Larusha Gramni et al.   INORGANICA CHIMICA ACTA

New platinum (II) and palladium (II) complexes of coumarin-thiazole Schiff base with a fluorescent chemosensor properties: Synthesis, spectroscopic characterization, X-ray structure determination, in vitro anticancer activity on various human carcinoma cell lines and computational studies

(2018) Ömer Şahin et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Stromal biology and therapy in pancreatic cancer: ready for clinical translation?

(2018) Albrecht Neesse et al.   GUT

Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcoma

(2018) Yvonne de Jong et al.   Oncogenesis

FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer

(2018) Thierry Conroy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tissue necrosis and its role in cancer progression

(2018) Adi Karsch-Bluman et al.   ONCOGENE

The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer

(2018) Yanfei Jia et al.   ONCOGENE

SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer

(2017) H Zhou et al.   ONCOGENE

BCL-XL directly modulates RAS signalling to favour cancer cell stemness

(2017) Sophie de Carné Trécesson et al.   Nature Communications

A rapid assessment for predicting drug-induced hepatotoxicity using zebrafish

(2017) Yun Zhang et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Overexpression of SOX18 correlates with accelerated cell growth and poor prognosis in human pancreatic ductal adenocarcinoma

(2016) Yazhou Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epidemiology of pancreatic cancer

(2016) Milena Ilic et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Identification of the Factors Responsible for the Selective in vitro Cytotoxic Activity of Isoprenylated Coumarin Derivatives under Nutrient-deprived Conditions

(2016) Hong Zhang et al.   Journal of Cancer

Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine

(2015) Claudia Fiorini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Gemcitabine resistance in pancreatic ductal adenocarcinoma

(2015) Yoav Binenbaum et al.   DRUG RESISTANCE UPDATES

Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses

(2015) Geir Bredholt et al.   Oncotarget

Synthesis and biological evaluation of isoprenylated coumarins as potential anti-pancreatic cancer agents

(2014) Maria Jun et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Roles for KRAS in Pancreatic Tumor Development and Progression

(2013) Marina Pasca di Magliano et al.   GASTROENTEROLOGY

SOX4 Transcriptionally Regulates Multiple SEMA3/Plexin Family Members and Promotes Tumor Growth in Pancreatic Cancer

(2012) Hsin-Yi Huang et al.   PLoS One

Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative

(2011) Tehsina Devji et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Anti-cancer activity of a novel palladium(II) complex on human breast cancer cells in vitro and in vivo

(2011) Engin Ulukaya et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Initial steps of metastasis: Cell invasion and endothelial transmigration

(2011) Franziska van Zijl et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Coumarins: Old Compounds with Novel Promising Therapeutic Perspectives

(2010) M. Riveiro et al.   CURRENT MEDICINAL CHEMISTRY

The Emerging Role of SOX Transcription Factors in Pancreatic Endocrine Cell Development and Function

(2009) Erin McDonald et al.   STEM CELLS AND DEVELOPMENT