A human kinase yeast array for the identification of kinases modulating phosphorylation‐dependent protein–protein interactions

Kinase drug discovery 20 years after imatinib: progress and future directions

(2021) Philip Cohen et al.   NATURE REVIEWS DRUG DISCOVERY

The disGeNET cytoscape app: exploring and visualizing disease genomics data

(2021) Janet Piñero et al.   Computational and Structural Biotechnology Journal

Exploring absent protein function in yeast: assaying post translational modification and human genetic variation

(2021) Christina S. Moesslacher et al.   Microbial Cell

Illuminating the kinome: Visualizing real-time kinase activity in biological systems using genetically encoded fluorescent protein-based biosensors

(2020) Danielle L. Schmitt et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

KinCon: Cell‐based recording of full‐length kinase conformations

(2020) Florian Enzler et al.   IUBMB LIFE

PAK5 facilitates the proliferation, invasion and migration in colorectal cancer cells

(2020) Silin Huang et al.   Cancer Medicine

Yeast-Based Genetic Interaction Analysis of Human Kinome

(2020) Jae-Hong Kim et al.   Cells

The Dark Kinase Knowledgebase: an online compendium of knowledge and experimental results of understudied kinases

(2020) Matthew E Berginski et al.   NUCLEIC ACIDS RESEARCH

Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells

(2020) Valentina Ranzuglia et al.   ONCOGENE

Illuminating the dark phosphoproteome

(2019) Elise J. Needham et al.   Science Signaling

A Combined Approach Reveals a Regulatory Mechanism Coupling Src’s Kinase Activity, Localization, and Phosphotransferase-Independent Functions

(2019) Ethan Ahler et al.   MOLECULAR CELL

Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

(2019) Bert van de Kooij et al.   eLife

The Landscape of Atypical and Eukaryotic Protein Kinases

(2019) Georgi K. Kanev et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Protein interaction perturbation profiling at amino-acid resolution

(2017) Jonathan Woodsmith et al.   NATURE METHODS

Identifying pathogenicity of human variants via paralog-based yeast complementation

(2017) Fan Yang et al.   PLoS Genetics

Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate

(2017) Thomas Corwin et al.   Cell Systems

An atlas of human kinase regulation

(2016) David Ochoa et al.   Molecular Systems Biology

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

(2016) James Campbell et al.   Cell Reports

Multi-scale perturbations of protein interactomes reveal their mechanisms of regulation, robustness and insights into genotype–phenotype maps

(2015) Marie Filteau et al.   Briefings in Functional Genomics

Estrogen receptor alpha phosphorylation and its functional impact in human breast cancer

(2015) Muralidharan Anbalagan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Phospho-tyrosine dependent protein-protein interaction network

(2015) A. Grossmann et al.   Molecular Systems Biology

Comprehensive characterization of the Published Kinase Inhibitor Set

(2015) Jonathan M Elkins et al.   NATURE BIOTECHNOLOGY

Version 4.0 of PaxDb: Protein abundance data, integrated across model organisms, tissues, and cell-lines

(2015) Mingcong Wang et al.   PROTEOMICS

Construction of phosphorylation interaction networks by text mining of full-length articles using the eFIP system

(2015) Catalina O. Tudor et al.   Database-The Journal of Biological Databases and Curation

A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein

(2015) Eva Absmeier et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

ANIA: ANnotation and Integrated Analysis of the 14-3-3 interactome

(2014) Michele Tinti et al.   Database-The Journal of Biological Databases and Curation

A general assay for monitoring the activities of protein tyrosine phosphatases in living eukaryotic cells

(2013) Leigh K. Harris et al.   ANALYTICAL BIOCHEMISTRY

Studying post-translational modifications with protein interaction networks

(2013) Jonathan Woodsmith et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural basis for dual roles of Aar2p in U5 snRNP assembly

(2013) G. Weber et al.   GENES & DEVELOPMENT

Construction of human activity-based phosphorylation networks

(2013) R. H. Newman et al.   Molecular Systems Biology

Crystal structure of Prp8 reveals active site cavity of the spliceosome

(2013) Wojciech P. Galej et al.   NATURE

Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells

(2013) Mikko Taipale et al.   NATURE BIOTECHNOLOGY

A Y2H-seq approach defines the human protein methyltransferase interactome

(2013) Mareike Weimann et al.   NATURE METHODS

Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface

(2013) I. J. De Vries-van Leeuwen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SGK regulation of renal sodium transport

(2012) Alan C. Pao   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome

(2012) Anna Hegele et al.   MOLECULAR CELL

The Saccharomyces cerevisiae W303-K6001 cross-platform genome sequence: insights into ancestry and physiology of a laboratory mutt

(2012) M. Ralser et al.   Open Biology

Mechanism for Aar2p function as a U5 snRNP assembly factor

(2011) G. Weber et al.   GENES & DEVELOPMENT

Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

(2011) Theonie Anastassiadis et al.   NATURE BIOTECHNOLOGY

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Phosphorylation in Protein-Protein Binding: Effect on Stability and Function

(2011) Hafumi Nishi et al.   STRUCTURE

The (un)targeted cancer kinome

(2010) Oleg Fedorov et al.   Nature Chemical Biology

Genotype to Phenotype: A Complex Problem

(2010) R. D. Dowell et al.   SCIENCE

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Protein Kinase CK2 in Health and Disease

(2009) O. Filhol et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Phosphatidylinositol 3-Kinase-dependent Activation of Mammalian Protein Kinase B/Akt inSaccharomyces cerevisiae, anin VivoModel for the Functional Study of Akt Mutations

(2009) Isabel Rodríguez-Escudero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis

(2009) L. O'Regan et al.   MOLECULAR AND CELLULAR BIOLOGY

Cyclin-dependent kinases: a family portrait

(2009) Marcos Malumbres et al.   NATURE CELL BIOLOGY

Positive Selection of Tyrosine Loss in Metazoan Evolution

(2009) C. S. H. Tan et al.   SCIENCE

Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases

(2009) C. S. H. Tan et al.   Science Signaling

Repeated two-hybrid screening detects transient protein–protein interactions

(2009) Arunachalam Vinayagam et al.   THEORETICAL CHEMISTRY ACCOUNTS

Contribution of the individual subunits of protein kinase CK2 and of hPrp3p to the splicing process

(2008) Janka Dörr et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Structure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1

(2008) Jungseog Kang et al.   MOLECULAR CELL

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

(2008) M. E. Hillenmeyer et al.   SCIENCE