The antibacterial and antioxidant efficacy and neutron sensing potency of 10B enriched hexagonal boron nitride nanoparticles

Current work reports the excellent antibacterial and antioxidant activities of the hexagonal boron nitride nanoparticles ((10)BNNPs) synthesized with enriched-Boron (B-10) in a horizontal dual-zone quartz tube furnace. The antibacterial activities of the as-synthesized (10)BNNPs are tested by using the well-diffusion technique. According to the antibacterial results, it has been found that B-10-NPs are highly responsive to K. pneumoniae and least responsive to P. aeruginosa bacterial strains. The antioxidant activity of (10)BNNPs is analyzed by scavenging free radicals of 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH) with time interval and variation in concentration of (BN)-B-10-NPs. The activity of DPPH scavenging of (10)BNNPs is observed by UV and visible light Spectrophotometer. The results show that the antioxidant potential of (10)BNNPs is up to 79.5%. In addition, the B-10-contents with a semiconductor nature, the synthesized (10)BNNPs offer a great potential to be used in Boron neutron capture therapy (BNCT) for tumor cells destruction and as a sensing element in a solid-state neutron detector.

Automated summary

This work demonstrates the excellent antibacterial and antioxidant activities of hexagonal boron nitride nanoparticles ((10)BNNPs) synthesized with enriched-Boron (B-10). The (10)BNNPs show high responsiveness to K. pneumoniae and low responsiveness to P. aeruginosa. Additionally, the (10)BNNPs exhibit a high antioxidant potential, making them promising for applications in Boron neutron capture therapy and solid-state neutron detectors.