Intracellular Self-Assembly of Peptides to Induce Apoptosis against Drug-Resistant Melanoma

Discovery and Development of Dolastatin 10-Derived Antibody Drug Conjugate Anticancer Drugs

(2022) Sheo B. Singh   JOURNAL OF NATURAL PRODUCTS

Polymer‐Based Drug‐Free Therapeutics for Anticancer, Anti‐Inflammatory, and Antibacterial Treatment

(2021) Marina Rodrigues Tavares et al.   MACROMOLECULAR BIOSCIENCE

A Reactive Oxygen Species-Tyrosinase Cascade-Activated Prodrug for Selectively Suppressing Melanoma

(2021) Guorui Li et al.   CCS Chemistry

Intracellular Condensates of Oligopeptide for Targeting Lysosome and Addressing Multiple Drug Resistance of Cancer

(2021) Jing Wang et al.   ADVANCED MATERIALS

Modulation of membrane–cytoskeleton interactions: ezrin as key player

(2021) Lei-Miao Yin et al.   TRENDS IN CELL BIOLOGY

Lysosome‐Targeted and Fluorescence‐Turned “On” Cytotoxicity Induced by Alkaline Phosphatase‐Triggered Self‐Assembly

(2021) Chengfan Wu et al.   Advanced Healthcare Materials

Chemical syntheses of bioinspired and biomimetic polymers toward biobased materials

(2021) Mitra S. Ganewatta et al.   Nature Reviews Chemistry

Peptide-based nanomaterials: Self-assembly, properties and applications

(2021) Tong Li et al.   Bioactive Materials

Metastatic melanoma

(2020) Ragini R. Kudchadkar et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo

(2020) Lu Zhang et al.   Nature Nanotechnology

Treatment of Advanced Melanoma in 2020 and Beyond

(2020) Russell W. Jenkins et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Materials design by synthetic biology

(2020) Tzu-Chieh Tang et al.   Nature Reviews Materials

Pulsed Microwave-Pumped Drug-Free Thermoacoustic Therapy by Highly Biocompatible and Safe Metabolic Polyarginine Probes

(2019) Shaodong Zhai et al.   NANO LETTERS

Genome-wide screening identifies novel genes and biological processes implicated in cisplatin resistance

(2019) Tengyu Ko et al.   FASEB JOURNAL

The Dominant Role of Oxygen in Modulating the Chemical Evolution Pathways of Tyrosine in Peptides: Dityrosine or Melanin

(2019) Xiaokang Ren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Actin Cytoskeleton and Focal Adhesions Regulate the Biased Migration of Breast Cancer Cells on Nanoscale Asymmetric Sawteeth

(2019) Song Chen et al.   ACS Nano

Pazopanib or methotrexate–vinblastine combination chemotherapy in adult patients with progressive desmoid tumours (DESMOPAZ): a non-comparative, randomised, open-label, multicentre, phase 2 study

(2019) Maud Toulmonde et al.   LANCET ONCOLOGY

Enzyme-Instructed Peptide Assemblies Selectively Inhibit Bone Tumors

(2019) Zhaoqianqi Feng et al.   Chem

Enzymatic Control of the Conformational Landscape of Supramolecular Assembling Peptides

(2018) Junfeng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress

(2018) Jennifer Tsoi et al.   CANCER CELL

An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential

(2018) Liqin Wang et al.   CELL

Enzymatic Self-Assembly Confers Exceptionally Strong Synergism with NF-κB Targeting for Selective Necroptosis of Cancer Cells

(2018) Jie Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically encoded lipid–polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly

(2018) Davoud Mozhdehi et al.   Nature Chemistry

Spatially resolved transcriptomics enables dissection of genetic heterogeneity in stage III cutaneous malignant melanoma

(2018) Kim Thrane et al.   CANCER RESEARCH

Human β-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability

(2018) Shih-Chieh Ti et al.   DEVELOPMENTAL CELL

Melanoma

(2018) Dirk Schadendorf et al.   LANCET

Translation deregulation in human disease

(2018) Soroush Tahmasebi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine

(2018) Hyun Jung Jun et al.   Nature Communications

Impact of Dopamine Oxidation on Dopaminergic Neurodegeneration

(2018) Shun Zhang et al.   ACS Chemical Neuroscience

Programmable Construction of Peptide-Based Materials in Living Subjects: From Modular Design and Morphological Control to Theranostics

(2018) Li-Li Li et al.   ADVANCED MATERIALS

Mechanisms of Cotranslational Maturation of Newly Synthesized Proteins

(2018) Günter Kramer et al.   Annual Review of Biochemistry

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

(2017) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anticancer potential of bioactive peptides from animal sources

(2017) Linghong Wang et al.   ONCOLOGY REPORTS

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

(2017) Lena F. Burbulla et al.   SCIENCE

Inhibition of cisplatin-resistance by RNA interference targeting metallothionein using reducible oligo-peptoplex

(2015) Jong-Hwan Lee et al.   JOURNAL OF CONTROLLED RELEASE

Drug-free macromolecular therapeutics – a new paradigm in polymeric nanomedicines

(2015) Te-Wei Chu et al.   Biomaterials Science

BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton

(2014) H Maes et al.   Cell Death & Disease

Perspectives on poly(dopamine)

(2013) Daniel R. Dreyer et al.   Chemical Science

In vivo modification of tyrosine residues in recombinant mussel adhesive protein by tyrosinase co-expression in Escherichia coli

(2012) Yoo Choi et al.   Microbial Cell Factories

New Challenges in Endpoints for Drug Development in Advanced Melanoma

(2011) A. Ribas et al.   CLINICAL CANCER RESEARCH