Improved Neuroprotection Provided by Drug Combination in Neurons Exposed to Cell-Derived Soluble Amyloid-β Peptide

Learning by Failing: Ideas and Concepts to Tackle γ-Secretases in Alzheimer's Disease and Beyond

(2015) Bart De Strooper et al.   Annual Review of Pharmacology and Toxicology

Oxidative Stress in Alzheimer’s Disease: Should We Keep Trying Antioxidant Therapies?

(2015) Michelli Erica Souza Ferreira et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Secreted Amyloid β-Proteins in a Cell Culture Model Include N-Terminally Extended Peptides That Impair Synaptic Plasticity

(2014) Alfred T. Welzel et al.   BIOCHEMISTRY

Lessons from a Failed γ-Secretase Alzheimer Trial

(2014) Bart De Strooper   CELL

Proteomic Analysis of C2C12 Myoblast and Myotube Exosome-Like Vesicles: A New Paradigm for Myoblast-Myotube Cross Talk?

(2014) Alexis Forterre et al.   PLoS One

Neuroprotective effects of resveratrol in Alzheimer disease pathology

(2014) Shraddha D. Rege et al.   Frontiers in Aging Neuroscience

Successes and Failures for Drugs in Late-Stage Development for Alzheimer’s Disease

(2013) Camryn Berk et al.   DRUGS & AGING

A cellular model of amyloid precursor protein processing and amyloid-β peptide production

(2013) MiMi P. Macias et al.   JOURNAL OF NEUROSCIENCE METHODS

Exacerbation of psoriatic skin lesions in a patient with Alzheimer disease receiving gamma-secretase inhibitor

(2013) Chao-Kai Hsu et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease

(2013) Rachelle S. Doody et al.   NEW ENGLAND JOURNAL OF MEDICINE

ω-3 Fatty Acids in the Prevention of Cognitive Decline in Humans

(2013) Tommy Cederholm et al.   Advances in Nutrition

Epidemiology of Dementias and Alzheimer’s Disease

(2012) Ana Luisa Sosa-Ortiz et al.   ARCHIVES OF MEDICAL RESEARCH

Protein Misfolded Oligomers: Experimental Approaches, Mechanism of Formation, and Structure-Toxicity Relationships

(2012) Francesco Bemporad et al.   CHEMISTRY & BIOLOGY

Synaptic changes in Alzheimer’s disease and its models

(2012) J. Pozueta et al.   NEUROSCIENCE

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease

(2011) Wei Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Aβ Oligomer-Induced Synapse Degeneration in Alzheimer’s Disease

(2011) Kyle C. Wilcox et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Critical role of cPLA2 in Aβ oligomer-induced neurodegeneration and memory deficit

(2011) Cédric Desbène et al.   NEUROBIOLOGY OF AGING

Docosahexaenoic acid and synaptic protection in Alzheimer's disease mice

(2010) Thierry Oster et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

(2010) Inna Kuperstein et al.   EMBO JOURNAL

Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease

(2010) Joseph F. Quinn et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Ciliary Neurotrophic Factor Cell-Based Delivery Prevents Synaptic Impairment and Improves Memory in Mouse Models of Alzheimer's Disease

(2010) P. Garcia et al.   JOURNAL OF NEUROSCIENCE

Synaptic degeneration in Alzheimer’s disease

(2009) Thomas Arendt   ACTA NEUROPATHOLOGICA

Cell-derived soluble oligomers of human amyloid-β peptides disturb cellular homeostasis and induce apoptosis in primary hippocampal neurons

(2009) Ting-Ting Yang et al.   JOURNAL OF NEURAL TRANSMISSION

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

(2009) Jennifer L. Tomic et al.   NEUROBIOLOGY OF DISEASE

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

N-truncated amyloid-β oligomers induce learning impairment and neuronal apoptosis

(2007) Ihsen Youssef et al.   NEUROBIOLOGY OF AGING