Characterization of cell-cell communication in autistic brains with single-cell transcriptomes

Anomalous collapses of Nares Strait ice arches leads to enhanced export of Arctic sea ice

(2021) G. W. K. Moore et al.   Nature Communications

Pan-cancer analysis of ligand-receptor crosstalk in the tumor microenvironment

(2021) Umesh Ghoshdastider et al.   CANCER RESEARCH

Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex

(2021) Kristen R. Maynard et al.   NATURE NEUROSCIENCE

Differences in subcortico-cortical interactions identified from connectome and microcircuit models in autism

(2021) Bo-yong Park et al.   Nature Communications

Gene Module Analysis Reveals Cell-Type Specificity and Potential Target Genes in Autism’s Pathogenesis

(2021) Guoli Ji et al.   Biomedicines

Recent ultra-rare inherited variants implicate new autism candidate risk genes

(2021) Amy B. Wilfert et al.   NATURE GENETICS

Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics

(2021) Sophia K. Longo et al.   NATURE REVIEWS GENETICS

Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

(2020) F. Kyle Satterstrom et al.   CELL

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

(2020) Mirjana Efremova et al.   Nature Protocols

Correction: Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

(2020) Michael S. Breen et al.   Translational Psychiatry

Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer’s Disease

(2020) Wei-Ting Chen et al.   CELL

Genome-wide detection of tandem DNA repeats that are expanded in autism

(2020) Brett Trost et al.   NATURE

Loss of Cntnap2 in the Rat Causes Autism‐Related Alterations in Social Interactions, Stereotypic Behavior, and Sensory Processing

(2020) Kaela E. Scott et al.   Autism Research

Predicting cell-to-cell communication networks using NATMI

(2020) Rui Hou et al.   Nature Communications

De novo missense variants disrupting protein–protein interactions affect risk for autism through gene co-expression and protein networks in neuronal cell types

(2020) Siwei Chen et al.   Molecular Autism

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

The influence of immune activation at early vs late gestation on fetal NRG1-ErbB4 expression and behavior in juvenile and adult mice offspring

(2019) F. Dabbah-Assadi et al.   BRAIN BEHAVIOR AND IMMUNITY

Association between CNTNAP2 polymorphisms and autism: A family-based study in the chinese han population and a meta-analysis combined with GWAS data of psychiatric genomics consortium

(2019) Tian Zhang et al.   Autism Research

Clinical and genetic analysis of children with a dual diagnosis of Tourette syndrome and autism spectrum disorder

(2019) Karin Vanessa Carias et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Single-cell genomics identifies cell type–specific molecular changes in autism

(2019) Dmitry Velmeshev et al.   SCIENCE

Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk

(2019) Santosh Kumar et al.   Journal of Neurodevelopmental Disorders

NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors

(2019) Hyejin Lee et al.   PLOS BIOLOGY

NicheNet: modeling intercellular communication by linking ligands to target genes

(2019) Robin Browaeys et al.   NATURE METHODS

Progress in the genetics of autism spectrum disorder

(2018) Marc Woodbury-Smith et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons

(2018) Ping Wang et al.   Translational Psychiatry

Levels of peripheral Neuregulin 1 are increased in non-medicated autism spectrum disorder patients

(2018) Erman Esnafoglu   JOURNAL OF CLINICAL NEUROSCIENCE

Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights

(2018) Itaru Kushima et al.   Cell Reports

Glia as architects of central nervous system formation and function

(2018) Nicola J. Allen et al.   SCIENCE

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

(2018) Mingfeng Li et al.   SCIENCE

Comprehensive functional genomic resource and integrative model for the human brain

(2018) Daifeng Wang et al.   SCIENCE

Oligodendrocyte differentiation of induced pluripotent stem cells derived from subjects with schizophrenias implicate abnormalities in development

(2018) Donna L. McPhie et al.   Translational Psychiatry

Neuregulin1 types mRNA level changes in autism spectrum disorder, and is associated with deficit in executive functions

(2018) Samane Abbasy et al.   EBioMedicine

Intercellular Signalling Cross-Talk: To Kill, To Heal and To Rejuvenate

(2017) Egor Y. Plotnikov et al.   Heart Lung and Circulation

Delineating the Common Biological Pathways Perturbed by ASD’s Genetic Etiology: Lessons from Network-Based Studies

(2017) Oded Oron et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

GeneAnalytics Pathway Analysis and Genetic Overlap among Autism Spectrum Disorder, Bipolar Disorder and Schizophrenia

(2017) Naveen Khanzada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders

(2017) L Yan et al.   MOLECULAR PSYCHIATRY

Decreased levels of serum fibroblast growth factor-2 in children with autism spectrum disorder

(2017) Erman Esnafoglu et al.   PSYCHIATRY RESEARCH

Neuroligin 2 nonsense variant associated with anxiety, autism, intellectual disability, hyperphagia, and obesity

(2016) Daniel J. Parente et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Single nucleotide polymorphisms in the CNTNAP2 gene in Brazilian patients with autistic spectrum disorder

(2016) P.P. Nascimento et al.   GENETICS AND MOLECULAR RESEARCH

Dysregulated fibroblast growth factor (FGF) signaling in neurological and psychiatric disorders

(2016) Cortney A. Turner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Emerging Picture of Autism Spectrum Disorder: Genetics and Pathology

(2015) Jason A. Chen et al.   Annual Review of Pathology-Mechanisms of Disease

Excess of rare, inherited truncating mutations in autism

(2015) Niklas Krumm et al.   NATURE GENETICS

Decreased plasma levels of neureglin-1 in drug naïve patients and chronic patients with schizophrenia

(2015) Ran Wang et al.   NEUROSCIENCE LETTERS

Differentiation of oligodendrocyte precursors is impaired in the prefrontal cortex in schizophrenia

(2015) Sarah A. Mauney et al.   SCHIZOPHRENIA RESEARCH

Autism spectrum disorder: advances in evidence-based practice

(2014) E. Anagnostou et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

The discovery of integrated gene networks for autism and related disorders

(2014) Fereydoun Hormozdiari et al.   GENOME RESEARCH

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Behavioral and Neuroanatomical Abnormalities in Pleiotrophin Knockout Mice

(2014) Jason W. Krellman et al.   PLoS One

Elevated serum levels of FGF-2, NGF and IGF-1 in patients with manic episode of bipolar disorder

(2014) Xiaohua Liu et al.   PSYCHIATRY RESEARCH

Contactins in the neurobiology of autism

(2013) Amila Zuko et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protein tyrosine phosphatases PTPδ, PTPσ, and LAR: presynaptic hubs for synapse organization

(2013) Hideto Takahashi et al.   TRENDS IN NEUROSCIENCES

Family History of Schizophrenia and Bipolar Disorder as Risk Factors for Autism

(2012) Patrick F. Sullivan et al.   ARCHIVES OF GENERAL PSYCHIATRY

Neuregulin 3 is associated with attention deficits in schizophrenia and bipolar disorder

(2012) Sandra Meier et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

FMRP targets distinct mRNA sequence elements to regulate protein expression

(2012) Manuel Ascano et al.   NATURE

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features

(2012) Joseph D Buxbaum et al.   Molecular Autism

Identification of rare X-linked neuroligin variants by massively parallel sequencing in males with autism spectrum disorder

(2012) Karyn Steinberg et al.   Molecular Autism

A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort

(2011) Jindan Yu et al.   Behavioral and Brain Functions

Axonally Derived Neuregulin-1 Is Required for Remyelination and Regeneration after Nerve Injury in Adulthood

(2011) F. R. Fricker et al.   JOURNAL OF NEUROSCIENCE

Rare structural variation of synapse and neurotransmission genes in autism

(2011) X Gai et al.   MOLECULAR PSYCHIATRY

Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

(2011) M. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SFARI Gene: an evolving database for the autism research community

(2010) S. Banerjee-Basu et al.   Disease Models & Mechanisms

Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus

(2010) Regina Dahlhaus et al.   HIPPOCAMPUS

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Association analysis of CNTNAP2 polymorphisms with autism in the Chinese Han population

(2010) Xiaoping Li et al.   PSYCHIATRIC GENETICS

Altered Functional Connectivity in Frontal Lobe Circuits Is Associated with Variation in the Autism Risk Gene CNTNAP2

(2010) A. A. Scott-Van Zeeland et al.   Science Translational Medicine

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

The NGL family of leucine-rich repeat-containing synaptic adhesion molecules

(2009) Jooyeon Woo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer

(2009) R Tabarés-Seisdedos et al.   MOLECULAR PSYCHIATRY

Differential distribution of neuregulin in human brain and spinal fluid

(2008) Mark S. Pankonin et al.   BRAIN RESEARCH