Design and synthesis of novel substituted indole-acrylamide derivatives and evaluation of their anti-cancer activity as potential tubulin-targeting agents

Induction of Apoptosis in Hepatocellular Carcinoma Cell Lines by Novel Indolylacrylamide Derivatives: Synthesis and Biological Evaluation

(2021) Mohammed Hawash et al.   CHEMISTRY & BIODIVERSITY

Goals and targets for personalized therapy for HCC

(2019) Thomas Couri et al.   Hepatology International

Structural insights into the design of indole derivatives as tubulin polymerization inhibitors

(2019) Yuanyuan Li et al.   FEBS LETTERS

Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agents

(2018) Nazan Inceler et al.   MedChemComm

Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics

(2017) Mohammed M.A. Hawash et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structural Basis of cis - and trans -Combretastatin Binding to Tubulin

(2017) Roberto Gaspari et al.   Chem

PLIP: fully automated protein–ligand interaction profiler

(2015) Sebastian Salentin et al.   NUCLEIC ACIDS RESEARCH

Identification of novel thiadiazoloacrylamide analogues as inhibitors of dengue-2 virus NS2B/NS3 protease

(2014) Hailong Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors

(2014) Sultan Nacak Baytas et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors

(2014) Guanghai Jin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle

(2013) Margit Rosner et al.   Nature Protocols

Transition-Metal-Free C-Arylation at Room Temperature by Arynes

(2012) Ranjeet A. Dhokale et al.   ORGANIC LETTERS

Classification and Toxicities of Vascular Disrupting Agents

(2011) Arman Hasani et al.   Clinical Lung Cancer

A novel regulatory event-based gene set analysis method for exploring global functional changes in heterogeneous genomic data sets

(2009) Chien-Yi Tung et al.   BMC GENOMICS

Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistance

(2009) E. A. Perez   MOLECULAR CANCER THERAPEUTICS