GLRA2 gene mutations cause high myopia in humans and mice

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

(2020) Pirro G. Hysi et al.   NATURE GENETICS

An overview of myopia genetics

(2019) Xue-Bi Cai et al.   EXPERIMENTAL EYE RESEARCH

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

(2018) Milly S. Tedja et al.   NATURE GENETICS

DIFFUSE CHORIORETINAL ATROPHY IN CHINESE HIGH MYOPIA

(2018) Ran Liu et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Structure-Function Analysis of the GlyR α2 Subunit Autism Mutation p.R323L Reveals a Gain-of-Function

(2017) Yan Zhang et al.   Frontiers in Molecular Neuroscience

Global causes of vision loss in 2015: are we on track to achieve the Vision 2020 target?

(2017) Charumathi Sabanayagam et al.   Lancet Global Health

Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050

(2016) Brien A. Holden et al.   OPHTHALMOLOGY

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

(2016) Qiao Fan et al.   Scientific Reports

The dynamic sclera: Extracellular matrix remodeling in normal ocular growth and myopia development

(2015) Angelica R. Harper et al.   EXPERIMENTAL EYE RESEARCH

Mutations of P4HA2 encoding prolyl 4-hydroxylase 2 are associated with nonsyndromic high myopia

(2015) Hui Guo et al.   GENETICS IN MEDICINE

Genetic and functional analyses demonstrate a role for abnormal glycinergic signaling in autism

(2015) M Pilorge et al.   MOLECULAR PSYCHIATRY

Crystal structure of human glycine receptor-α3 bound to antagonist strychnine

(2015) Xin Huang et al.   NATURE

The contribution of de novo coding mutations to autism spectrum disorder

(2014) Ivan Iossifov et al.   NATURE

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

(2013) Virginie J M Verhoeven et al.   NATURE GENETICS

A novel missense mutation in theNYXgene associated with high myopia

(2013) Shea Ping Yip et al.   OPHTHALMIC AND PHYSIOLOGICAL OPTICS

Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia

(2013) Amy K. Kiefer et al.   PLoS Genetics

Common Mechanisms Underlying Refractive Error Identified in Functional Analysis of Gene Lists From Genome-Wide Association Study Results in 2 European British Cohorts

(2013) Pirro G. Hysi et al.   JAMA Ophthalmology

Causes of vision loss worldwide, 1990–2010: a systematic analysis

(2013) Rupert R A Bourne et al.   Lancet Global Health

Cross inhibition from ON to OFF pathway improves the efficiency of contrast encoding in the mammalian retina

(2012) Zhiyin Liang et al.   JOURNAL OF NEUROPHYSIOLOGY

Selective Glycine Receptor  2 Subunit Control of Crossover Inhibition between the On and Off Retinal Pathways

(2012) R. D. Nobles et al.   JOURNAL OF NEUROSCIENCE

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia

(2010) A Piton et al.   MOLECULAR PSYCHIATRY

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Corneal elevation and thickness in relation to the refractive status measured with the Pentacam Scheimpflug system

(2008) Ömür Ö. Uçakhan et al.   JOURNAL OF CATARACT AND REFRACTIVE SURGERY

The Time Course of Transmitter at Glycinergic Synapses onto Motoneurons

(2008) M. Beato   JOURNAL OF NEUROSCIENCE

Biometric measurement of the mouse eye using optical coherence tomography with focal plane advancement

(2008) Xiangtian Zhou et al.   VISION RESEARCH