4.3 Article

Dietary patterns and endometrial cancer risk in the California Teachers Study cohort

Journal

CANCER CAUSES & CONTROL
Volume 26, Issue 4, Pages 627-634

Publisher

SPRINGER
DOI: 10.1007/s10552-015-0552-1

Keywords

Dietary patterns; Endometrial cancer; Body mass index; Cohort

Funding

  1. National Cancer Institute [R01 CA77398]
  2. California Department of Public Health (CDPH) [103885]
  3. NCI's SEER program [HHSN261201000140C, HHSN261201000035C, HHSN261201000034C]
  4. Centers for Disease Control and Prevention's (CDCP) National Program of Cancer Registries [U58DP003862-01]
  5. NATIONAL CANCER INSTITUTE [R01CA077398] Funding Source: NIH RePORTER
  6. NATIONAL CENTER FOR CHRONIC DISEASE PREV AND HEALTH PROMO [U58DP003862] Funding Source: NIH RePORTER

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Information on the role of dietary patterns and endometrial cancer risk is limited. We investigated whether dietary patterns are associated with endometrial cancer risk among women in the California Teachers Study cohort. Among 75,093 eligible women, 937 developed invasive endometrial cancer between 1995 and 2011. Multivariate Cox regression was performed to estimate relative risks (RR) and 95 % confidence intervals (CI) associated with five dietary patterns identified by principal components factor analysis: plant-based, high protein/high fat, high carbohydrates, ethnic, and salad and wine. These dietary patterns were not associated with endometrial cancer risk overall (RR = 0.91, 95 % CI: 0.72, 1.15 for the highest vs. lowest quintile of the plant-based dietary pattern) or by menopausal status and hormone therapy use. Dietary patterns do not seem to be associated with endometrial cancer risk.

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