GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER

ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway

(2021) Tianyao Xiao et al.   Life Science Alliance

A nuclear-based quality control pathway for non-imported mitochondrial proteins

(2021) Viplendra PS Shakya et al.   eLife

Simple-to-use CRISPR-SpCas9/SaCas9/AsCas12a vector series for genome editing in Saccharomyces cerevisiae

(2021) Satoshi Okada et al.   G3-Genes Genomes Genetics

Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction

(2020) Lan Wang et al.   eLife

The Mitochondrial Import Complex MIM Functions as Main Translocase for α-Helical Outer Membrane Proteins

(2020) Kim Nguyen Doan et al.   Cell Reports

The AAA+ ATPase Msp1 is a processive protein translocase with robust unfoldase activity

(2020) Dominic T. Castanzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial AAA‐ATPase Msp1 detects mislocalized tail‐anchored proteins through a dual‐recognition mechanism

(2019) Lanlan Li et al.   EMBO REPORTS

Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins

(2019) Verena Dederer et al.   eLife

Msp1 Clears Mistargeted Proteins by Facilitating Their Transfer from Mitochondria to the ER

(2019) Shunsuke Matsumoto et al.   MOLECULAR CELL

Fine-tuning the expression of target genes using a DDI2 promoter gene switch in budding yeast

(2019) Yong Wang et al.   Scientific Reports

The GET pathway can increase the risk of mitochondrial outer membrane proteins to be mistargeted to the ER

(2018) Daniela G. Vitali et al.   JOURNAL OF CELL SCIENCE

An ER surface retrieval pathway safeguards the import of mitochondrial membrane proteins in yeast

(2018) Katja G. Hansen et al.   SCIENCE

Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins

(2017) Matthew L. Wohlever et al.   MOLECULAR CELL

The ER membrane protein complex is a transmembrane domain insertase

(2017) Alina Guna et al.   SCIENCE

The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane

(2017) Nicholas R Weir et al.   eLife

The SND proteins constitute an alternative targeting route to the endoplasmic reticulum

(2016) Naama Aviram et al.   NATURE

Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins

(2014) Y.-C. Chen et al.   EMBO JOURNAL

The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins

(2014) V. Okreglak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An expanded tool kit for the auxin-inducible degron system in budding yeast

(2013) Magdalena Morawska et al.   YEAST

Get3 is a holdase chaperone and moves to deposition sites for aggregated proteins when membrane targeting is blocked

(2012) K. Powis et al.   JOURNAL OF CELL SCIENCE

Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast

(2012) R. Scott McIsaac et al.   NUCLEIC ACIDS RESEARCH

A portrait of the GET pathway as a surprisingly complicated young man

(2012) Vladimir Denic   TRENDS IN BIOCHEMICAL SCIENCES

The mechanism of membrane-associated steps in tail-anchored protein insertion

(2011) Malaiyalam Mariappan et al.   NATURE

Targeting pathways of C-tail-anchored proteins

(2010) Nica Borgese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Comprehensive Characterization of Genes Required for Protein Folding in the Endoplasmic Reticulum

(2009) M. C. Jonikas et al.   SCIENCE

The GET Complex Mediates Insertion of Tail-Anchored Proteins into the ER Membrane

(2008) Maya Schuldiner et al.   CELL