Gliadin induced oxidative stress and altered cellular responses in human intestinal cells: An in‐vitro study to understand the cross‐talk between the transcription factor Nrf‐2 and multifunctional APE1 enzyme

Mitigation of Gliadin-Induced Inflammation and Cellular Damage by Curcumin in Human Intestinal Cell Lines

(2021) Kunj Bihari Gupta et al.   INFLAMMATION

Glycyrrhiza glabra (Licorice) root extract attenuates doxorubicin-induced cardiotoxicity via alleviating oxidative stress and stabilising the cardiac health in H9c2 cardiomyocytes

(2020) Shishir Upadhyay et al.   JOURNAL OF ETHNOPHARMACOLOGY

Impact of the APE1 Redox Function Inhibitor E3330 in Non-Small Cell Lung Cancer Cells Exposed to Cisplatin: Increased Cytotoxicity and Impairment of Cell Migration and Invasion

(2020) Rita Manguinhas et al.   Antioxidants

Organophosphate‐pesticides induced survival mechanisms and APE1‐mediated Nrf2 regulation in non‐small‐cell lung cancer cells

(2020) Shweta Thakur et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Immunoreactive cereal proteins in wheat allergy, non-celiac gluten/wheat sensitivity (NCGS) and celiac disease

(2019) Katharina Anne Scherf   Current Opinion in Food Science

Nrf2–ARE Signaling Acts as Master Pathway for the Cellular Antioxidant Activity of Fisetin

(2019) Huihui Zhang et al.   MOLECULES

Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis

(2018) Prashant Singh et al.   Clinical Gastroenterology and Hepatology

Gliadin effect on the oxidative balance and DNA damage: An in-vitro , ex - vivo study

(2018) Erika Monguzzi et al.   DIGESTIVE AND LIVER DISEASE

Mesalazine treatment in organotypic culture of celiac patients: Comparative study with gluten free diet

(2018) Elisabetta Benedetti et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inflammatory response of gliadin protein isolated from various wheat varieties on human intestinal cell line

(2018) Kunj Bihari Gupta et al.   JOURNAL OF CEREAL SCIENCE

Oxidative stress stimulates invasive potential in rat C6 and human U-87 MG glioblastoma cells via activation and cross-talk between PKM2, ENPP2 and APE1 enzymes

(2018) Ravi P. Cholia et al.   METABOLIC BRAIN DISEASE

Colorectal Adenoma Risk Is Increased among Recently Diagnosed Adult Celiac Disease Patients

(2018) Juan Lasa et al.   Gastroenterology Research and Practice

Oxidative stress as a biomarker for monitoring treated celiac disease

(2018) Sarah Moretti et al.   Clinical and Translational Gastroenterology

Redox signaling in the gastrointestinal tract

(2017) Salvador Pérez et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phytochemical Ginkgolide B Attenuates Amyloid-β1-42 Induced Oxidative Damage and Altered Cellular Responses in Human Neuroblastoma SH-SY5Y Cells

(2017) Iqbal Gill et al.   JOURNAL OF ALZHEIMERS DISEASE

Curcumin revitalizes Amyloid beta (25–35)-induced and organophosphate pesticides pestered neurotoxicity in SH-SY5Y and IMR-32 cells via activation of APE1 and Nrf2

(2017) Bibekananda Sarkar et al.   METABOLIC BRAIN DISEASE

APE1 modulates cellular responses to organophosphate pesticide-induced oxidative damage in non-small cell lung carcinoma A549 cells

(2017) Shweta Thakur et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Glutathione redox cycle in small intestinal mucosa and peripheral blood of pediatric celiac disease patients

(2017) Vesnać Stojiljković et al.   ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS

Design, structure activity relationship, cytotoxicity and evaluation of antioxidant activity of curcumin derivatives/analogues

(2016) Pramod K. Sahu   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Systematic review: noncoeliac gluten sensitivity

(2015) J. Molina-Infante et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions

(2015) S. Thakur et al.   CELL BIOCHEMISTRY AND FUNCTION

Non-Celiac Gluten Sensitivity Triggers Gut Dysbiosis, Neuroinflammation, Gut-Brain Axis Dysfunction, and Vulnerability for Dementia

(2015) Mak Daulatzai   CNS & Neurological Disorders-Drug Targets

APE1 promotes antioxidant capacity by regulating Nrf-2 function through a redox-dependent mechanism

(2015) Jin-Lu Shan et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Overlap between Irritable Bowel Syndrome and Non-Celiac Gluten Sensitivity: A Clinical Dilemma

(2015) Archita Makharia et al.   Nutrients

Gliadin Peptides as Triggers of the Proliferative and Stress/Innate Immune Response of the Celiac Small Intestinal Mucosa

(2014) Maria Barone et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

P47phox−/− Mice Are Compromised in Expansion and Activation of CD8+ T Cells and Susceptible to Trypanosoma cruzi Infection

(2014) Monisha Dhiman et al.   PLoS Pathogens

Wheat Allergy and Intolerence; Recent Updates and Perspectives

(2013) Imran Pasha et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Curcumin Pretreatment Induces Nrf2 and an Antioxidant Response and Prevents Hemin-Induced Toxicity in Primary Cultures of Cerebellar Granule Neurons of Rats

(2013) Susana González-Reyes et al.   Oxidative Medicine and Cellular Longevity

Metalaxyl-induced changes in the antioxidant metabolism of Solanum nigrum L. suspension cells

(2013) Alexandra de Sousa et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

MnSOD tg Mice Control Myocardial Inflammatory and Oxidative Stress and Remodeling Responses Elicited in Chronic Chagas Disease

(2013) Monisha Dhiman et al.   Journal of the American Heart Association

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction

(2012) Anil K. Mantha et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Celiac Disease, Inflammation and Oxidative Damage: A Nutrigenetic Approach

(2012) Gianna Ferretti et al.   Nutrients

Estimation of Lipid Peroxidation Induced by Hydrogen Peroxide in Cultured Human Lymphocytes

(2011) Yasir Hasan Siddique et al.   Dose-Response

Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution

(2011) Keiko Taguchi et al.   GENES TO CELLS

Identification of genes differentially expressed during interaction of resistant and susceptible apple cultivars (Malus × domestica) with Erwinia amylovora

(2010) Angela Baldo et al.   BMC PLANT BIOLOGY

Antioxidant status and lipid peroxidation in small intestinal mucosa of children with celiac disease

(2009) Vesna Stojiljković et al.   CLINICAL BIOCHEMISTRY

Trypanosoma cruzi infection disturbs mitochondrial membrane potential and ROS production rate in cardiomyocytes

(2009) Shivali Gupta et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lysosomal accumulation of gliadin p31-43 peptide induces oxidative stress and tissue transglutaminase-mediated PPAR  downregulation in intestinal epithelial cells and coeliac mucosa

(2009) A. Luciani et al.   GUT

Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells

(2009) C.-Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Regulatory Functions of Mammalian AP-Endonuclease (APE1/Ref-1), an Essential Multifunctional Protein

(2008) Kishor K. Bhakat et al.   ANTIOXIDANTS & REDOX SIGNALING

The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme

(2008) Gianluca Tell et al.   ANTIOXIDANTS & REDOX SIGNALING

Unusual Role of a Cysteine Residue in Substrate Binding and Activity of Human AP-Endonuclease 1

(2008) Anil K. Mantha et al.   JOURNAL OF MOLECULAR BIOLOGY