Distinct Subcellular Localization of a Type I CRISPR Complex and the Cas3 Nuclease in Bacteria

A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression

(2021) Rachael E. Workman et al.   CELL

Critical Anti-CRISPR Locus Repression by a Bi-functional Cas9 Inhibitor

(2020) Beatriz A. Osuna et al.   Cell Host & Microbe

Listeria Phages Induce Cas9 Degradation to Protect Lysogenic Genomes

(2020) Beatriz A. Osuna et al.   Cell Host & Microbe

Bacterial alginate regulators and phage homologs repress CRISPR–Cas immunity

(2020) Adair L. Borges et al.   Nature Microbiology

A Type I-F Anti-CRISPR Protein Inhibits the CRISPR-Cas Surveillance Complex by ADP-Ribosylation

(2020) Yiying Niu et al.   MOLECULAR CELL

Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry

(2019) MaryClare F. Rollins et al.   MOLECULAR CELL

Direct Visualization of Native CRISPR Target Search in Live Bacteria Reveals Cascade DNA Surveillance Mechanism

(2019) Jochem N.A. Vink et al.   MOLECULAR CELL

Visualisation of dCas9 target search in vivo using an open-microscopy framework

(2019) Koen J. A. Martens et al.   Nature Communications

High-throughput screen reveals sRNAs regulating crRNA biogenesis by targeting CRISPR leader to repress Rho termination

(2019) Ping Lin et al.   Nature Communications

A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases

(2019) Senén D. Mendoza et al.   NATURE

Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants

(2019) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Bacteriophage Cooperation Suppresses CRISPR-Cas3 and Cas9 Immunity

(2018) Adair L. Borges et al.   CELL

Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity

(2018) Mariann Landsberger et al.   CELL

Structure basis for RNA-guided DNA degradation by Cascade and Cas3

(2018) Yibei Xiao et al.   SCIENCE

Determining the Specificity of Cascade Binding, Interference, and Primed Adaptation In Vivo in the Escherichia coli Type I-E CRISPR-Cas System

(2018) Lauren A. Cooper et al.   mBio

Discovery of widespread Type I and Type V CRISPR-Cas inhibitors

(2018) Nicole D. Marino et al.   SCIENCE

Assembly and Translocation of a CRISPR-Cas Primed Acquisition Complex

(2018) Kaylee E. Dillard et al.   CELL

Structural basis of CRISPR–SpyCas9 inhibition by an anti-CRISPR protein

(2017) De Dong et al.   NATURE

Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity

(2017) MaryClare F. Rollins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetics of dCas9 target search inEscherichia coli

(2017) Daniel Lawson Jones et al.   SCIENCE

Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade

(2017) Chaoyou Xue et al.   Cell Reports

Disabling Cas9 by an anti-CRISPR DNA mimic

(2017) Jiyung Shin et al.   Science Advances

Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems

(2016) Adrian G. Patterson et al.   MOLECULAR CELL

Structural basis of Cas3 inhibition by the bacteriophage protein AcrF3

(2016) Xiaofei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CRISPR-Cas: biology, mechanisms and relevance

(2016) Frank Hille et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quorum sensing controls thePseudomonas aeruginosaCRISPR-Cas adaptive immune system

(2016) Nina M. Høyland-Kroghsbo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The solution structure of an anti-CRISPR protein

(2016) Karen L. Maxwell et al.   Nature Communications

Structural basis of Cas3 inhibition by the bacteriophage protein AcrF3

(2016) Xiaofei Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gifsy-1 Prophage IsrK with Dual Function as Small and Messenger RNA Modulates Vital Bacterial Machineries

(2016) Tal Hershko-Shalev et al.   PLoS Genetics

Phage DNA Dynamics in Cells with Different Fates

(2015) Qiuyan Shao et al.   BIOPHYSICAL JOURNAL

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System

(2015) Sy Redding et al.   CELL

I can see CRISPR now, even when phage are gone

(2015) Hannah K. Ratner et al.   CURRENT OPINION IN INFECTIOUS DISEASES

CRISPR-Cas immunity in prokaryotes

(2015) Luciano A. Marraffini   NATURE

Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins

(2015) Joseph Bondy-Denomy et al.   NATURE

Unravelling the structural and mechanistic basis of CRISPR–Cas systems

(2014) John van der Oost et al.   NATURE REVIEWS MICROBIOLOGY

CRISPR-Cas systems: new players in gene regulation and bacterial physiology

(2014) Timothy R. Sampson et al.   Frontiers in Cellular and Infection Microbiology

Massive Activation of Archaeal Defense Genes during Viral Infection

(2013) T. E. F. Quax et al.   JOURNAL OF VIROLOGY

The General Phosphotransferase System Proteins Localize to Sites of Strong Negative Curvature in Bacterial Cells

(2013) S. Govindarajan et al.   mBio

The CRISPR/Cas Adaptive Immune System of Pseudomonas aeruginosa Mediates Resistance to Naturally Occurring and Engineered Phages

(2012) K. C. Cady et al.   JOURNAL OF BACTERIOLOGY

CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

(2012) Edze R. Westra et al.   MOLECULAR CELL

Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System

(2012) Dipali G. Sashital et al.   MOLECULAR CELL

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system

(2012) Joe Bondy-Denomy et al.   NATURE

Phage-Induced Expression of CRISPR-Associated Proteins Is Revealed by Shotgun Proteomics in Streptococcus thermophilus

(2012) Jacque C. Young et al.   PLoS One

Structural basis for CRISPR RNA-guided DNA recognition by Cascade

(2011) Matthijs M Jore et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

(2011) B. Wiedenheft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription Profile of Thermus thermophilus CRISPR Systems after Phage Infection

(2009) Yoshihiro Agari et al.   JOURNAL OF MOLECULAR BIOLOGY