Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment

Antibody-drug conjugates (ADCs) for cancer therapy: Strategies, challenges, and successes

(2018) Meghdad Abdollahpour-Alitappeh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Breaking Down the Barriers to Precision Cancer Nanomedicine

(2017) Christina von Roemeling et al.   TRENDS IN BIOTECHNOLOGY

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

RETRACTED ARTICLE: VEGF Silencing Inhibits Human Osteosarcoma Angiogenesis and Promotes Cell Apoptosis via PI3K/AKT Signaling Pathway

(2015) Jian Zhao et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Intratumoral Heterogeneity: From Diversity Comes Resistance

(2015) A. Pribluda et al.   CLINICAL CANCER RESEARCH

Nanocarriers for cancer-targeted drug delivery

(2015) Preeti Kumari et al.   JOURNAL OF DRUG TARGETING

Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia

(2014) Rakesh K. Jain   CANCER CELL

Cationic Nanogel-mediated Runx2 and Osterix siRNA Delivery Decreases Mineralization in MC3T3 Cells

(2014) Arun R. Shrivats et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

The tumor microenvironment at a glance

(2013) F. R. Balkwill et al.   JOURNAL OF CELL SCIENCE

Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers

(2013) Rakesh K. Jain   JOURNAL OF CLINICAL ONCOLOGY

Autotransfecting Short Interfering RNA through Facile Covalent Polymer Escorts

(2013) Saadyah E. Averick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

Internalization Mechanisms of the Epidermal Growth Factor Receptor after Activation with Different Ligands

(2013) Lasse Henriksen et al.   PLoS One

Polyspermine Imidazole-4,5-imine, a Chemically Dynamic and Biologically Responsive Carrier System for Intracellular Delivery of siRNA

(2012) Shiyue Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modeling the proton sponge hypothesis: examining proton sponge effectiveness for enhancing intracellular gene delivery through multiscale modeling

(2012) Eric C. Freeman et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Physicochemical Characteristics of Nanoparticles Affect Circulation, Biodistribution, Cellular Internalization, and Trafficking

(2012) Xiaopin Duan et al.   Small

Surface Charge Affects Cellular Uptake and Intracellular Trafficking of Chitosan-Based Nanoparticles

(2011) Zhan-Guo Yue et al.   BIOMACROMOLECULES

Anti-tumor activity of liposome encapsulated fluoroorotic acid as a single agent and in combination with liposome irinotecan

(2011) Kareen Riviere et al.   JOURNAL OF CONTROLLED RELEASE

Interaction of Cholesterol-Conjugated Ionizable Amino Lipids with Biomembranes: Lipid Polymorphism, Structure–Activity Relationship, and Implications for siRNA Delivery

(2011) Jingtao Zhang et al.   LANGMUIR

Therapeutic Mechanism and Efficacy of the Antibody-Drug Conjugate BAY 79-4620 Targeting Human Carbonic Anhydrase 9

(2011) H. M. Petrul et al.   MOLECULAR CANCER THERAPEUTICS

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

Modulating Pharmacokinetics, Tumor Uptake and Biodistribution by Engineered Nanoparticles

(2011) Rochelle R. Arvizo et al.   PLoS One

Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation

(2011) Sachie Hiratsuka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

(2011) Daniel J. Siegwart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles

(2010) Chunbai He et al.   BIOMATERIALS

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Frontiers in cancer nanomedicine: directing mass transport through biological barriers

(2010) Mauro Ferrari   TRENDS IN BIOTECHNOLOGY

Immunohistochemical analysis of integrins αvβ3, αvβ5 and α5β1, and their ligands, fibrinogen, fibronectin, osteopontin and vitronectin, in frozen sections of human oral head and neck squamous cell carcinomas

(2010) EVA-MARIA FABRICIUS et al.   Experimental and Therapeutic Medicine

RNA interference screening for the discovery of oncology targets

(2009) Kim Quon et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The mechanisms on apoptosis by inhibiting VEGF expression in human breast cancer cells

(2009) Yin-Lin Ge et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody-Cytotoxic Drug Conjugate

(2008) G. D. Lewis Phillips et al.   CANCER RESEARCH

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS