Journal
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
Volume 32, Issue 3, Pages 366-371Publisher
BMJ PUBLISHING GROUP
DOI: 10.1136/ijgc-2021-002462
Keywords
ovarian cancer; radiation; quality of life (pro); palliative care
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Epithelial ovarian cancer is a rare malignancy with poor prognosis, treated mainly with surgery and chemotherapy. Previously, radiotherapy was also used, but it is no longer standard practice. Modern radiotherapy techniques are emerging as potential options for the treatment of ovarian cancer.
Epithelial ovarian cancer accounts for around 1.9% of all malignancies and often presents late at an advanced stage. Prognosis is therefore poor. Currently the mainstay of treatment is radical cytoreductive surgery and chemotherapy but, in the past, the standard of care also included adjuvant whole abdominal radiotherapy. This is no longer standard practice, largely due to high toxicity rates and the effectiveness of platinum-based chemotherapy. Presently, a role is emerging for modern radiotherapy techniques in both the salvage and palliative settings. This review aims to examine the historical use of radiotherapy in ovarian cancer before looking forward to its potential future role.
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