Bcl-2 family member Mcl-1 expression is reduced under hypoxia by the E3 ligase FBW7 contributing to BNIP3 induced cell death in glioma cells

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3

(2014) Meghan B. Azad et al.   Autophagy

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Extended adjuvant temozolomide with cis-retinoic acid for adult glioblastoma

(2012) M.W. Pitz et al.   Current Oncology

Delving deeper: MCL-1's contributions to normal and cancer biology

(2012) Rhonda M. Perciavalle et al.   TRENDS IN CELL BIOLOGY

Mcl-1 and FBW7 Control a Dominant Survival Pathway Underlying HDAC and Bcl-2 Inhibitor Synergy in Squamous Cell Carcinoma

(2012) Lei He et al.   Cancer Discovery

Bnip3-mediated defects in oxidative phosphorylation promote mitophagy

(2011) Robert L. Thomas et al.   Autophagy

Targeting ErbB Receptors in High-Grade Glioma

(2011) Sabina Berezowska et al.   CURRENT PHARMACEUTICAL DESIGN

Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia

(2011) Jessica M. Cassavaugh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer

(2011) E P Booy et al.   ONCOGENE

Truncated forms of BNIP3 act as dominant negatives inhibiting hypoxia-induced cell death

(2010) Nicolle Bristow et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

ERBB2 Induces an Antiapoptotic Expression Pattern of Bcl-2 Family Members in Node-Negative Breast Cancer

(2010) I. B. Petry et al.   CLINICAL CANCER RESEARCH

Superoxide is the major reactive oxygen species regulating autophagy

(2009) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

BNIP3 (Bcl-2 19 kDa Interacting Protein) Acts as Transcriptional Repressor of Apoptosis-Inducing Factor Expression Preventing Cell Death in Human Malignant Gliomas

(2009) T. R. Burton et al.   JOURNAL OF NEUROSCIENCE

Proliferation of Human Glioblastoma Stem Cells Occurs Independently of Exogenous Mitogens

(2009) John J. P. Kelly et al.   STEM CELLS

Mcl-1 is a potential therapeutic target in multiple types of cancer

(2008) C. Akgul   CELLULAR AND MOLECULAR LIFE SCIENCES