A bivalent recombinant immunotoxin with high potency against tumors with EGFR and EGFRvIII expression

Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance

(2015) Kimmo J. Hatanpaa et al.   NEOPLASIA

A novel recombinant immunotoxin-based therapy targeting wild-type and mutant EGFR improves survival in murine models of glioblastoma

(2014) Vidyalakshmi Chandramohan et al.   OncoImmunology

Current challenges and clinical investigations of epidermal growth factor receptor (EGFR)- and ErbB family-targeted agents in the treatment of head and neck squamous cell carcinoma (HNSCC)

(2013) Roger B. Cohen   CANCER TREATMENT REVIEWS

Construction of an Immunotoxin, D2C7-(scdsFv)-PE38KDEL, Targeting EGFRwt and EGFRvIII for Brain Tumor Therapy

(2013) V. Chandramohan et al.   CLINICAL CANCER RESEARCH

Diphtheria toxin-based targeted toxin therapy for brain tumors

(2013) Yan Michael Li et al.   JOURNAL OF NEURO-ONCOLOGY

The quest to overcome resistance to EGFR-targeted therapies in cancer

(2013) Curtis R Chong et al.   NATURE MEDICINE

Targeting EGFR for Treatment of Glioblastoma: Molecular Basis to Overcome Resistance

(2012) T. E. Taylor et al.   CURRENT CANCER DRUG TARGETS

Bacteria and their Toxins Tamed for Immunotherapy

(2012) Irena Adkins et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Effect of pre-existing anti-diphtheria toxin antibodies on T cell depletion levels following diphtheria toxin-based recombinant anti-monkey CD3 immunotoxin treatment

(2012) Abraham J. Matar et al.   TRANSPLANT IMMUNOLOGY

An Anti-PSMA Bivalent Immunotoxin Exhibits Specificity and Efficacy for Prostate Cancer Imaging and Therapy

(2012) Fayun Zhang et al.   Advanced Healthcare Materials

EGFR-Targeted Therapy in Malignant Glioma: Novel Aspects and Mechanisms of Drug Resistance

(2012) Hui-Wen Lo   Current Molecular Pharmacology

Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies

(2011) P. C. De Witt Hamer   NEURO-ONCOLOGY

Combination of Phosphorylated and Truncated EGFR Correlates With Higher Tumor and Nodal Stage in Head and Neck Cancer

(2010) James Keller et al.   CANCER INVESTIGATION

New Strategies in Head and Neck Cancer: Understanding Resistance to Epidermal Growth Factor Receptor Inhibitors

(2010) L. F. Chen et al.   CLINICAL CANCER RESEARCH

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

(2010) M.-d.-M. Inda et al.   GENES & DEVELOPMENT

Denileukin diftitox: a novel immunotoxin

(2009) George Manoukian et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Mechanisms of Antileukemic Activity of the Novel Bcl-2 Homology Domain-3 Mimetic GX15-070 (Obatoclax)

(2008) M. Konopleva et al.   CANCER RESEARCH

GMP production and characterization of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1) for phase I/II clinical trials

(2007) Jung Hee Woo et al.   PROTEIN EXPRESSION AND PURIFICATION