4.6 Article

Healthy eating and all-cause mortality among Chinese aged 80 years or older

Publisher

BMC
DOI: 10.1186/s12966-022-01280-6

Keywords

Dietary pattern; Healthy eating index; Mortality; Oldest-old; Chinese; CLHLS

Funding

  1. National Key R&D Program of China [2018YFC2000400]
  2. National Natural Sciences Foundation of China [72061137004]
  3. U.S. National Institute of Aging of National Institute of Health [P01AG031719]

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This study analyzed the association between dietary patterns and mortality risk among Chinese adults aged 80 years and older, finding that healthier eating patterns were significantly associated with a reduced risk of all-cause mortality in this population.
Background There is little evidence of the influence of dietary patterns on mortality risk among adults 80 years or older (oldest-old). We evaluated the association between the Simplified Healthy Eating index (SHE-index) and mortality among Chinese oldest-old. Methods Population-based cohort study from the Chinese Longitudinal Healthy Longevity Survey (CLHLS 1998-2014, n = 35 927), conducted in 22 Chinese provinces, were pooled for analysis. The first seven waves of the CLHLS (1998, 2000, 2002, 2005, 2008-09, 2011-12, and 2013-2014) were utilized, with follow-up to the last wave (2018) (range 0-21 years). The SHE-index was collected in each wave, and was constructed from intake frequency of nine dietary variables, with a higher score indicating better diet quality. Cox proportional hazards model with dietary patterns as a time-varying exposure was employed to analyze the relationship between SHE-index and mortality. Results At baseline, the median age of all participants was 92 years (25th percentile, 85 years; 75th percentile, 100 years). In multivariable models, the hazard ratios (95% confidence intervals) for SHE-index quartile 2, quartile 3 and quartile 4 versus quartile1 were 0.91 (0.88, 0.93), 0.89 (0.86, 0.92) and 0.82 (0.78, 0.85), respectively. Results were generally consistent for men and women and in a large number of sensitivity analyses. Conclusions Healthier eating patterns were associated with a significant reduction in the risk of all-cause mortality among Chinese oldest-old, lending support to the importance of life-long adherence to healthy diet into advanced old age.

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