4.8 Article

Esophageal Motility Disorders: Current Approach to Diagnostics and Therapeutics

Journal

GASTROENTEROLOGY
Volume 162, Issue 6, Pages 1617-1634

Publisher

W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.gastro.2021.12.289

Keywords

Absent Contractility; Achalasia; Barium Esophagram; Distal Esophageal Spasm; Esophagogastric Junction; Esophageal Motility Disorders; FLIP; High-Resolution Manometry; Hyper-contractile Esophagus; Ineffective Esophageal Motility

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This review discusses the current approach to diagnosis and therapeutics of various esophageal motility disorders, which is of great significance in improving the quality of life for patients.
Dysphagia is a common symptom with significant impact on quality of life. Our diagnostic armamentarium was primarily limited to endoscopy and barium esophagram until the advent of manometric techniques in the 1970s, which provided the first reliable tool for assessment of esophageal motor function. Since that time, significant advances have been made over the last 3 decades in our understanding of various esophageal motility disorders due to improvement in diagnostics with high-resolution esophageal manometry. High-resolution esophageal manometry has improved the sensitivity for detecting achalasia and has also enhanced our understanding of spastic and hypomotility disorders of the esophageal body. In this review, we discuss the current approach to diagnosis and therapeutics of various esophageal motility disorders.

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