Topical ocular drug delivery systems: Innovations for an unmet need
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Title
Topical ocular drug delivery systems: Innovations for an unmet need
Authors
Keywords
Drug delivery, Ocular drugs, Eye drops, Pharmacology, Emulsions, Ointments, Nanoparticles, Ocular inserts
Journal
EXPERIMENTAL EYE RESEARCH
Volume 218, Issue -, Pages 109006
Publisher
Elsevier BV
Online
2022-03-04
DOI
10.1016/j.exer.2022.109006
References
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Note: Only part of the references are listed.- Topical Bimatoprost Insert for Primary Open-Angle Glaucoma and Ocular Hypertension Treatment - A Phase II Controlled Study
- (2021) Francine Rubião et al. Current Drug Delivery
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- Tailored gatifloxacin Pluronic® F-68-loaded contact lens: Addressing the issue of transmittance and swelling
- (2020) Furqan A. Maulvi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Advances and limitations of drug delivery systems formulated as eye drops
- (2020) Clotilde Jumelle et al. JOURNAL OF CONTROLLED RELEASE
- Ophthalmic Medication Expenditures and Out-of-pocket Spending: An analysis of US prescriptions from 2007-2016
- (2020) Evan M. Chen et al. OPHTHALMOLOGY
- Hydrogel Biomaterials for Application in Ocular Drug Delivery
- (2020) Courtney R. Lynch et al. Frontiers in Bioengineering and Biotechnology
- Multiple drug delivery from the drug-implants-laden silicone contact lens: Addressing the issue of burst drug release
- (2020) Ankita R. Desai et al. Materials Science & Engineering C-Materials for Biological Applications
- Safety and Efficacy of Nepafenac Punctal Plug Delivery System in Controlling Postoperative Ocular Pain and Inflammation following Cataract Surgery
- (2020) Eric D. Donnenfeld et al. JOURNAL OF CATARACT AND REFRACTIVE SURGERY
- Extraocular, periocular, and intraocular routes for sustained drug delivery for glaucoma
- (2020) Uday B. Kompella et al. PROGRESS IN RETINAL AND EYE RESEARCH
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- (2020) Brunella Grassiri et al. ADVANCES IN COLLOID AND INTERFACE SCIENCE
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- (2020) Rupert Bourne et al. Lancet Global Health
- Effect of gold nanoparticles on timolol uptake and its release kinetics from contact lenses: In vitro and in vivo evaluation
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- (2019) Shaimaa S. Ibrahim JOURNAL OF PHARMACEUTICAL SCIENCES
- Drug delivery systems and novel formulations to improve treatment of rare corneal disease
- (2019) Jorge Jimenez et al. DRUG DISCOVERY TODAY
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- (2019) Brian Pall et al. CORNEA
- New technique to reduce systemic side effects of timolol eye drops: the tissue press method ‐ cross‐over clinical trial
- (2019) Luzia Müller et al. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
- Autologous Serum-Based Eye Drops for Treatment of Ocular Surface Disease
- (2019) Roni M. Shtein et al. OPHTHALMOLOGY
- Advanced Formulation Approaches for Ocular Drug Delivery: State-Of-The-Art and Recent Patents
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- Iontophoretic Dexamethasone Phosphate Compared to Topical Prednisolone Acetate 1% for Noninfectious Anterior Segment Uveitis
- (2019) John Sheppard et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Chitosan/hydroxyethyl cellulose inserts for sustained-release of dorzolamide for glaucoma treatment: In vitro and in vivo evaluation
- (2019) Juçara R. Franca et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Supramolecular cyclodextrin complex: Diversity, safety, and applications in ocular therapeutics
- (2019) Pinal Chaudhari et al. EXPERIMENTAL EYE RESEARCH
- Iontophoresis enhances voriconazole antifungal potency and corneal penetration
- (2019) Guilherme M. Gelfuso et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Management of herpes simplex virus epithelial keratitis
- (2018) Mehdi Roozbahani et al. CURRENT OPINION IN OPHTHALMOLOGY
- Topical drug delivery devices: A review
- (2018) Christian J.F. Bertens et al. EXPERIMENTAL EYE RESEARCH
- Hyaluronic-acid-modified lipid-polymer hybrid nanoparticles as an efficient ocular delivery platform for moxifloxacin hydrochloride
- (2018) Dan Liu et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- A comprehensive review on contact lens for ophthalmic drug delivery
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- Polymer-based carriers for ophthalmic drug delivery
- (2018) Julieta C. Imperiale et al. JOURNAL OF CONTROLLED RELEASE
- Therapeutic Contact Lenses with Polymeric Vehicles for Ocular Drug Delivery: A Review
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- A comprehensive insight on ocular pharmacokinetics
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- Autologous serum and plasma rich in growth factors in ophthalmology: preclinical and clinical studies
- (2015) Eduardo Anitua et al. ACTA OPHTHALMOLOGICA
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- (2015) Phillip Dixon et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Ocular pharmacology
- (2015) Gary D. Novack et al. JOURNAL OF CLINICAL PHARMACOLOGY
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- (2015) Noriaki Nagai et al. Journal of Oleo Science
- The Most Common Barriers to Glaucoma Medication Adherence
- (2015) Paula Anne Newman-Casey et al. OPHTHALMOLOGY
- Mydriasert pupillary dilation for cataract surgery: an economic and clinical study
- (2015) Ameet Shah et al. BMC Ophthalmology
- On formulating ophthalmic emulsions
- (2014) Roozbeh Mafi et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Comparison of Clinical Efficacies of Autologous Serum Eye Drops in Patients With Primary and Secondary Sjögren Syndrome
- (2014) Jehyung Hwang et al. CORNEA
- Autologous serum eye drops diluted with sodium hyaluronate: clinical and experimental comparative study
- (2013) José S. López-García et al. ACTA OPHTHALMOLOGICA
- Antimicrobial compounds in tears
- (2013) Alison M. McDermott EXPERIMENTAL EYE RESEARCH
- Hyaluronic acid-based nanocomposite hydrogels for ocular drug delivery applications
- (2013) Leonardus Kresna Widjaja et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Distribution of Cyclosporine A in Ocular Tissues After Topical Administration of Cyclosporine A Cationic Emulsions to Pigmented Rabbits
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- (2012) Yang Kyung Cho et al. CURRENT EYE RESEARCH
- Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: In vitro and pharmacokinetics studies
- (2012) R.S. Bhatta et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
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- (2012) Hyun Jung Jung et al. JOURNAL OF CONTROLLED RELEASE
- A New Look at Lubrication of the Ocular Surface: Fluid Mechanics Behind the Blinking Eyelids
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- (2012) Tilman Schmoll et al. OPTOMETRY AND VISION SCIENCE
- Individualised patient care as an adjunct to standard care for promoting adherence to ocular hypotensive therapy: an exploratory randomised controlled trial
- (2011) T A Gray et al. EYE
- Sustained in vivo release from imprinted therapeutic contact lenses
- (2011) A. Tieppo et al. JOURNAL OF CONTROLLED RELEASE
- The Relationship between Glaucoma Medication Adherence, Eye Drop Technique, and Visual Field Defect Severity
- (2011) Betsy Sleath et al. OPHTHALMOLOGY
- The influence of health literacy level on an educational intervention to improve glaucoma medication adherence
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- (2010) Ripal Gaudana et al. AAPS Journal
- Adherence with brimonidine in patients with glaucoma aware and not aware of electronic monitoring
- (2010) Manuel Marcel Hermann et al. ACTA OPHTHALMOLOGICA
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- (2010) Robert Fish et al. CURRENT OPINION IN OPHTHALMOLOGY
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- The effect of iodide iontophoresis on the antioxidative capacity of the tear fluid
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- Measurement of Adherence to Brimonidine Therapy for Glaucoma Using Electronic Monitoring
- (2010) Manuel Marcel Hermann et al. JOURNAL OF GLAUCOMA
- Applications of nanoparticles in ophthalmology
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- Readability of prescription labels and medication recall in a population of tertiary referral glaucoma patients
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- (2008) Ioannis A. Sogias et al. BIOMACROMOLECULES
- Functions of ocular surface mucins in health and disease
- (2008) Flavio Mantelli et al. Current Opinion in Allergy and Clinical Immunology
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- A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery: Rheological, mucoadhesive and in vitro release properties
- (2008) L MAYOL et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Challenges and solutions in topical ocular drug-delivery systems
- (2008) Maryam Ali et al. Expert Review of Clinical Pharmacology
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