Neuropeptide B/W receptor 1 peptidomimetic agonists: Structure-activity relationships and plasma stability

Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in Mice

(2021) Sanju Narayanan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fragment-based lead discovery of a novel class of small molecule antagonists of neuropeptide B/W receptor subtype 1 (GPR7)

(2020) Remond Moningka et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and Pharmacological Evaluation of 1-Phenyl-3-Thiophenylurea Derivatives as Cannabinoid Type-1 Receptor Allosteric Modulators

(2019) Thuy Nguyen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phoenixin-14 stimulates proliferation and insulin secretion in insulin producing INS-1E cells

(2019) Maria Billert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

An overview of Ca2+mobilization assays in GPCR drug discovery

(2017) Qiang Ma et al.   Expert Opinion on Drug Discovery

The Current State of Peptide Drug Discovery: Back to the Future?

(2017) Antoine Henninot et al.   JOURNAL OF MEDICINAL CHEMISTRY

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

Strategic Approaches to Optimizing Peptide ADME Properties

(2014) Li Di   AAPS Journal

Identification of Neuropeptide S Antagonists: Structure–Activity Relationship Studies, X-ray Crystallography, and in Vivo Evaluation

(2014) Carla Hassler et al.   ACS Chemical Neuroscience

Identifying structural determinants of potency for analogs of apelin-13: Integration of C-terminal truncation with structure–activity

(2014) Yanyan Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7)

(2012) Mariangela Urbano et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists

(2012) Miguel Guerrero et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Turning Receptors On and Off with Intracellular Pepducins: New Insights into G-protein-coupled Receptor Drug Development

(2012) Katie O'Callaghan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropeptide B and W regulate leptin and resistin secretion, and stimulate lipolysis in isolated rat adipocytes

(2012) Marek Skrzypski et al.   REGULATORY PEPTIDES

Analgesic Neuropeptide W Suppresses Seizures in the Brain Revealed by Rational Repositioning and Peptide Engineering

(2010) Brad R. Green et al.   ACS Chemical Neuroscience