Article
Cardiac & Cardiovascular Systems
Masafumi Ono, Patrick W. Serruys, Hironori Hara, Hideyuki Kawashima, Chao Gao, Rutao Wang, Kuniaki Takahashi, Neil O'Leary, Joanna J. Wykrzykowska, Faisal Sharif, Jan J. Piek, Scot Garg, Michael J. Mack, David R. Holmes, Marie-Claude Morice, Stuart J. Head, Arie Pieter Kappetein, Daniel J. F. M. Thuijs, Thilo Noack, Piroze M. Davierwala, Friedrich W. Mohr, David J. Cohen, Yoshinobu Onuma
Summary: This study investigated the impact of revascularization strategies on long-term survival and quality of life in elderly patients over 70 years old. The findings suggest that there was no significant difference in 10-year survival rate, life expectancy, 5-year MACCE, and 5-year QOL between elderly patients undergoing PCI or CABG.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Tong Ding, Xin Yuan, Kai Chen, Liuzhong Shen, Changdong Guan, Feng Lv, Hui Xiong, Bo Xu, Yongjian Wu, Shengshou Hu
Summary: This study compared the long-term outcomes of hybrid coronary revascularization (HCR) with coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for multivessel disease. The results showed that HCR performed better than PCI in terms of major adverse cardiac and cerebrovascular events and functional status.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Medicine, General & Internal
Jaskanwal Deep Singh Sara, Elad Maor, Diana Orbelo, Rajiv Gulati, Lliach O. Lerman, Amir Lerman
Summary: This study found a significant association between a noninvasive voice biomarker and incident CAD events at follow-up, which may have important clinical implications for the remote and noninvasive screening of patients to identify those at risk of coronary disease and its complications.
MAYO CLINIC PROCEEDINGS
(2022)
Review
Medicine, General & Internal
Guillermo Romero-Farina, Santiago Aguade-Bruix
Summary: Cardiovascular disease remains the leading cause of death globally, with an increasing prevalence of coronary artery disease (CAD). Planning the follow-up of patients with stable chronic CAD requires a comprehensive understanding of clinical history, utilization of imaging techniques for risk stratification, and the need for further studies to improve follow-up planning for scCAD patients in the future.
Article
Medicine, General & Internal
Quentin Delbaere, Myriam Akodad, Francois Roubille, Benoit Lattuca, Guillaume Cayla, Florence Leclercq
Summary: Survival rate without neurological sequelae at one year after resuscitated cardiac arrest is high, with satisfactory overall quality of life. Older age, lower body mass index, and lower initial Left Ventricle Ejection Fraction were associated with poorer outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Aysun Erdem Yaman, Ufuk Sadik Ceylan
Summary: Vitamin D levels are associated with long-term cardiac events in patients with coronary artery disease, and vitamin D deficiency is linked to an increased risk of non-ST-elevated myocardial infarction and unstable angina.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cell Biology
Daniel Valente Batista, Whady Hueb, Eduardo Gomes Lima, Paulo Cury Rezende, Cibele Larrosa Garzillo, Rosa Maria Rahmi Garcia, Jaime Paula Pessoa Linhares Filho, Eduardo Bello Martins, Carlos Vicente Serrano Junior, Jose Antonio Franchini Ramires, Roberto Kalil Filho
Summary: This study found that lower eGFR levels were associated with higher rates of MACE and mortality in patients with DM2 and CAD, and the surgical treatment group had lower rates of adverse cardiovascular events and additional revascularization. eGFR was identified as an independent predictor of MACE and mortality.
Article
Medicine, General & Internal
Baran Balcan, Yeliz Celik, Jennifer Newitt, Patrick J. Strollo, Yuksel Peker
Summary: This study found that female sex and BMI were related to REM-predominant OSA in a cohort of patients with coronary artery disease. In the multivariate model, MCS was inversely associated with REM-AHI.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jung-Min Ahn, Do-Yoon Kang, Sung-Cheol Yun, Seung Ho Hur, Hun-Jun Park, Damras Tresukosol, Woong Chol Kang, Hyuck Moon Kwon, Seung-Woon Rha, Do-Sun Lim, Myung-Ho Jeong, Bong-Ki Lee, He Huang, Young Hyo Lim, Jang Ho Bae, Byung Ok Kim, Tiong Kiam Ong, Sung Gyun Ahn, Cheol-Hyun Chung, Duk-Woo Park, Seung-Jung Park
Summary: There were no significant differences between PCI and CABG in the long-term outcomes of patients with multivessel coronary artery disease.
Article
Cardiac & Cardiovascular Systems
Alexander R. van Rosendael, A. Maxim Bax, Inge J. van den Hoogen, Jeff M. Smit, Subhi J. Al'Aref, Stephan Achenbach, Mouaz H. Al-Mallah, Daniele Andreini, Daniel S. Berman, Matthew J. Budoff, Filippo Cademartiri, Tracy Q. Callister, Hyuk-Jae Chang, Kavitha Chinnaiyan, Benjamin J. W. Chow, Ricardo C. Cury, Augustin DeLago, Gudrun Feuchtner, Martin Hadamitzky, Joerg Hausleiter, Philipp A. Kaufmann, Yong-Jin Kim, Jonathon A. Leipsic, Erica Maffei, Hugo Marques, Pedro de Araujo Goncalves, Gianluca Pontone, Gilbert L. Raff, Ronen Rubinshtein, Todd C. Villines, Heidi Gransar, Yao Lu, Jessica M. Pena, Fay Y. Lin, Leslee J. Shaw, Jagat Narula, James K. Min, Jeroen J. Bax
Summary: This study evaluated the relationship between dyspnoea, coronary artery disease (CAD), and major cardiovascular events (MACE). The findings suggest that dyspnoea is associated with severe obstructive CAD, and the severity of obstructive CAD explains the elevated MACE rates in patients with dyspnoea.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Review
Biochemistry & Molecular Biology
Pietro Scicchitano, Micaela De Palo, Giuseppe Parisi, Margherita Ilaria Gioia, Marco Matteo Ciccone
Summary: The impact of coronary artery disease (CAD) on mortality and disabilities is well-established. Revascularization procedures have reduced adverse cardiovascular events in atherosclerosis patients, with coronary artery bypass graft (CABG) being recommended for specific alterations in the coronary tree. Doppler ultrasonography (DU) may serve as a reliable technique for assessing the patency of left internal mammary artery (LIMA) graft in CABG patients. This review aims to evaluate the impact of DU on LIMA graft patency evaluation in post-CABG follow-up.
Article
Cardiac & Cardiovascular Systems
Xueyan Zhao, Lianjun Xu, Lin Jiang, Jian Tian, Yin Zhang, Dong Wang, Kai Sun, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Lei Song, Jinqing Yuan
Summary: In this study, PCI and CABG were associated with a lower risk of death and MACCE compared to MT for patients with diabetes and TVD. The results emphasize the importance of appropriate revascularization for these patients, with CABG showing a lower risk of MACCE compared to PCI. Further comprehensive treatment may be beneficial in the future.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Nursing
Anu Nurmeksela, Vuokko Pihlainen, Tarja Kettunen, Jari Laukkanen, Jaana Peltokoski
Summary: Nurse-led counseling and systematic follow-up are effective in reducing cardiovascular risk factor levels, with significant improvements in cholesterol levels and waist circumference observed among coronary artery disease patients. Patients evaluated nurse-led counseling positively, but further research is needed to enhance self-management and counseling strategies for this population.
NURSING & HEALTH SCIENCES
(2021)
Review
Cardiac & Cardiovascular Systems
Danilo Neglia, Natallia Maroz-Vadalazhskaya, Nazario Carrabba, Riccardo Liga
Summary: In recent decades, effective management of cardiovascular risk factors has led to a decrease in coronary artery disease prevalence. However, coronary heart disease remains a leading cause of death globally, and chronic coronary syndromes continue to be targets of cardiac imaging and invasive procedures. Current guidelines recommend non-invasive imaging for CCS patients to identify high-risk individuals for referral to invasive procedures, but recent studies have raised questions about the efficacy of coronary revascularization. The role of imaging in these patients, including those with ischemic cardiomyopathy, remains debated.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Endocrinology & Metabolism
B. Savitsky, O. Manor, G. Lawrence, Y. Friedlander, D. S. Siscovick, H. Hochner
Summary: This study provides evidence supporting the mismatch hypothesis, showing that the accumulation of effects from a non-beneficial environment has the strongest detrimental impact on obesity outcomes. Additionally, a mismatch between developmental and later environments may lead to maladaptation of the individual, resulting in obesity.
INTERNATIONAL JOURNAL OF OBESITY
(2021)
Article
Cardiac & Cardiovascular Systems
Mario Gaudino, Irbaz Hameed, Antonino Di Franco, Ajita Naik, Michelle Demetres, Giuseppe Biondi-Zoccai, Sripal Bangalore
Summary: This study conducted a systematic review and meta-analysis to compare the efficacy of percutaneous coronary intervention and coronary artery bypass grafting stratified by SYNTAX score. The results showed no significant association between SYNTAX score and the comparative effectiveness of the two procedures.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Health Care Sciences & Services
Theresa M. Coles, Nicole Lucas, Molly McFatrich, Debra Henke, Jennifer L. Ridgeway, Emma M. Behnken, Kevin Weinfurt, Bryce B. Reeve, Amy Corneli, Shannon M. Dunlay, John A. Spertus, Li Lin, Ileana L. Pina, Fraser D. Bocell, Michelle E. Tarver, Heidi Dohse, Anindita Saha, Brittany Caldwell
Summary: The purpose of this study is to evaluate potential gender-based differences in interpreting the KCCQ-23 and explore aspects of HRQOL not captured by the questionnaire. The findings indicate that there were no significant differences in interpreting the questionnaire between men and women, but some modifications may improve interpretation for a wide range of patients.
QUALITY OF LIFE RESEARCH
(2023)
Letter
Cardiac & Cardiovascular Systems
Ruby Havistin, Suvasini Lakshmanan, Matthew J. Budoff
JACC-CARDIOVASCULAR IMAGING
(2023)
Review
Cardiac & Cardiovascular Systems
Ilana S. Golub, Orly G. Termeie, Stephanie Kristo, Lucia P. Schroeder, Suvasini Lakshmanan, Ahmed M. Shafter, Luay Hussein, Dhiran Verghese, Jairo Aldana-Bitar, Venkat S. Manubolu, Matthew J. Budoff
Summary: This review provides a summary of global guidelines on coronary artery calcium (CAC) for atherosclerotic cardiovascular disease risk assessment in both clinical and preventive settings. The review compares recommendations from different cardiovascular societies worldwide and identifies common features. Although there are some differences in specific intervals and cut points, international guidelines emphasize the importance of CAC in both primary and secondary prevention of atherosclerotic cardiovascular disease. Understanding the similarities among international guidelines is crucial for clinicians to make informed decisions about personalized treatment.
JACC-CARDIOVASCULAR IMAGING
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Matthew J. Budoff
Article
Cardiac & Cardiovascular Systems
Padma Kaul, Sarah Rathwell, Carolyn S. P. Lam, Cynthia M. Westerhout, John A. Spertus, Kevin J. Anstrom, Robert O. Blaustein, Justin A. Ezekowitz, Burkert Pieske, Lothar Roessig, Javed Butler, Paul W. Armstrong
Summary: This study investigated the association between frailty and health status in patients with heart failure with preserved ejection fraction (HFpEF). The results showed that patient-reported frailty was modestly correlated with the KCCQ-PLS and 6MWD, and could offer prognostic insight into 6MWD at 24 weeks.
JACC-HEART FAILURE
(2023)
Article
Cardiac & Cardiovascular Systems
Nina Talmor, Michael Gurin, Nathaniel Smilowitz, Dana Gossett, Bruria Eisner, Mitchell Pleasure, Harmony R. Reynolds
Summary: This case report describes a 37-year-old woman with recurrent non-ST elevation myocardial infarction (NSTEMI) during her menstrual periods. Intracoronary acetylcholine provocation testing revealed coronary spasm in the left anterior descending artery (LAD) that was relieved with nitroglycerine. Initiating calcium channel blockade and suppressing cyclical variation in sex hormones improved her symptoms and prevented monthly NSTEMI events caused by coronary spasm.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Kashvi Gupta, John A. Spertus, Mary Birmingham, Kensey L. Gosch, Mansoor Husain, Dalane W. Kitzman, Bertram Pitt, Sanjiv J. Shah, James L. Januzzi, Ildiko Lingvay, Javed Butler, Mikhail Kosiborod, David E. Lanfear
Summary: The health status of Black patients with heart failure is worse compared to White patients. Sodium-glucose cotransporter 2 inhibitors (SGLT2is) can reduce cardiovascular mortality and improve health status in heart failure patients, but it is unclear if the effect is similar across races. The study found that SGLT2i improves health status equally for Black and White patients.
Article
Cardiac & Cardiovascular Systems
Mark G. Rabbat, Suvasini Lakshmanan, Mina M. Benjamin, Gheorghe Doros, April Kinninger, Matthew J. Budoff, Deepak L. Bhatt
Summary: The EVAPORATE trial demonstrated that IPE significantly reduced plaque burden. This study assessed the impact of IPE on coronary physiology using FFRCT. The results showed that IPE improved coronary distal segment FFRCT, providing mechanistic insight into the clinical benefit observed in the REDUCE-IT trial.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Mariane Cecilia dos Reis, Juliana Araujo Nascimento, Geisa Nascimento de Andrade, Ana Claudia de Souza Costa, Julio Yoshio Takada, Antonio de Padua Mansur, Edimar Alcides Bocchi, Gianni Mara Silva dos Santos, John A. Spertus, Naomi Kondo Nakagawa
Summary: The Portuguese version of the KCCQ-12 questionnaire has high internal consistency and construct validity in assessing the health status of patients with chronic heart failure. It can be confidently used in Brazil for research and clinical care.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2023)
Article
Cardiac & Cardiovascular Systems
Scott D. J. Solomon, Charles J. S. Lowenstein, Ankeet S. Bhatt, Alexander Peikert, Orly N. Vardeny, Mikhail N. S. Kosiborod, Jeffrey S. R. Berger, Harmony R. Reynolds, Stephanie Mavromichalis, Anya D. Barytol, Andrew D. F. Althouse, James F. S. Luther, Eric S. L. Leifer, Andrei L. Kindzelski, Mary N. Cushman, Michelle N. Z. Gong, Lucy Z. Kornblith, Pooja S. Khatri, Keri S. Kim, Lisa Baumann Kreuziger, Lana Wahid, Bridget-Anne W. Kirwan, Mark W. D. Geraci, Matthew D. S. Neal, Judith S. Hochman
Summary: This study aimed to evaluate the efficacy of using the P-selectin inhibitor crizanlizumab in reducing mortality and disease progression in COVID-19 patients. However, the results showed that the drug did not improve organ support-free days in patients hospitalized with COVID-19.
Review
Biology
Leonid Bershtein, Alexey Sumin, Elizaveta Zbyshevskaya, Victoria Gumerova, Darejan Tsurtsumia, Igor Kochanov, Alina Andreeva, Vartan Piltakian, Sergey Sayganov
Summary: Coronary revascularization is a commonly studied treatment for stable coronary artery disease (SCAD), but there is no consensus among experts regarding its indications. This article examines the main statements from significant American and European guidelines on myocardial revascularization, and analyzes the appropriateness of revascularization based on new research data, including the ISCHEMIA study and the ACC/AHA 2021 Revascularization Guidelines. The article also discusses the findings and potential significance of revascularization in SCAD based on data from the ISCHEMIA study, including sub-analyses in controversial subgroups and a substudy in patients with chronic kidney disease (CKD).
Article
Cardiac & Cardiovascular Systems
Patrick W. Serruys, Nozomi Kotoku, Bjarne L. Norgaard, Scot Garg, Koen Nieman, Marc R. Dweck, Jeroen J. Bax, Juhani Knuuti, Jagat Narula, Divaka Perera, Charles A. Taylor, Jonathon A. Leipsic, Edward D. Nicol, Nicolo Piazza, Carl J. Schultz, Kakuya Kitagawa, Bernard De Bruyne, Carlos Collet, Kaoru Tanaka, Saima Mushtaq, Marta Belmonte, Darius Dudek, Adriana Zlahoda-Huzior, Shengxian Tu, William Wijns, Faisal Sharif, Matthew J. Budoff, Johan de Mey, Daniele Andreini, Yoshinobu Onuma
Summary: Coronary computed tomographic angiography (CCTA) has become the preferred investigation for determining the presence and haemodynamic significance of coronary artery disease. It can rule out atherosclerosis or detect subclinical plaque in patients without significant epicardial obstruction, and provide risk classification. For ischaemic non-obstructive coronary arteries, non-invasive imaging, including CCTA, is also expected. In patients with significant epicardial obstruction, CCTA can assist in planning revascularisation by determining disease complexity, vessel size, lesion length, tissue composition of the atherosclerotic plaque, and the best fluoroscopic viewing angle.
Review
Cardiac & Cardiovascular Systems
Pamela Pina, Daniel Lorenzatti, Rita Paula, Jonathan Daich, Aldo L. Schenone, Carlos Gongora, Mario J. Garcia, Michael J. Blaha, Matthew J. Budoff, Daniel S. Berman, Salim S. Virani, Leandro Slipczuk
Summary: Atherosclerotic cardiovascular disease (ASCVD) is a ongoing epidemic, primarily caused by lipid abnormalities. Despite being asymptomatic, most individuals who experience a first ASCVD event do not receive preventative therapies. Risk calculators based on traditional risk factors have been the cornerstone of primary prevention, but they often misclassify individuals, resulting in ineffective use of lipid-lowering medication or missed opportunities for prevention. The development of coronary artery calcium scoring (CAC) and CT coronary angiography (CCTA) provide tools to visualize coronary plaque and guide personalized lipid management.
AMERICAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Orly Leiva, Eugene Yuriditsky, Radu Postelnicu, Eric H. Yang, Vikramjit Mukherjee, Allison Greco, James Horowitz, Carlos Alviar, Sripal Bangalore
Summary: Among cancer patients with intermediate or high-risk PE, treatment with CBT was associated with a lower risk of in-hospital death or cardiac arrest but a higher risk of bleeding.
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
(2023)