TNF-α-induced E3 ligase, TRIM15 inhibits TNF-α-regulated NF-κB pathway by promoting turnover of K63 linked ubiquitination of TAK1

Gene activation precedes DNA demethylation in response to infection in human dendritic cells

(2019) Alain Pacis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The proinflammatory cytokine TNF-α induces DNA demethylation–dependent and –independent activation of interleukin-32 expression

(2019) Zuodong Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TNIP1‐mediated TNF‐α/NF‐κB signalling cascade sustains glioma cell proliferation

(2019) Qingchun Lei et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells

(2019) Ghizlane Maarifi et al.   Science Advances

TRIM8 regulated autophagy modulates the level of cleaved Caspase-3 subunit to inhibit genotoxic stress induced cell death

(2018) Milton Roy et al.   CELLULAR SIGNALLING

K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains

(2018) Fumiaki Ohtake et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor Necrosis Factor Alpha-Induced Recruitment of Inflammatory Mononuclear Cells Leads to Inflammation and Altered Brain Development in Murine Cytomegalovirus-Infected Newborn Mice

(2017) Maria C. Seleme et al.   JOURNAL OF VIROLOGY

The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

(2017) Yong Tae Kwon et al.   TRENDS IN BIOCHEMICAL SCIENCES

TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis

(2017) Shigetsugu Hatakeyama   TRENDS IN BIOCHEMICAL SCIENCES

Expression profiling of TRIM protein family in THP1-derived macrophages following TLR stimulation

(2017) Mei-Xiu Jiang et al.   Scientific Reports

Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity

(2016) Marios G Koliopoulos et al.   EMBO JOURNAL

The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling

(2016) Fumiaki Ohtake et al.   MOLECULAR CELL

TNF biology, pathogenic mechanisms and emerging therapeutic strategies

(2015) George D. Kalliolias et al.   Nature Reviews Rheumatology

TRIM family proteins: emerging class of RING E3 ligases as regulator of NF-κB pathway

(2014) Dhanendra Tomar et al.   BIOLOGY OF THE CELL

Structural insights into the TRIM family of ubiquitin E3 ligases

(2014) Yang Li et al.   CELL RESEARCH

TRIM38 inhibits TNF - and IL-1 -triggered NF- B activation by mediating lysosome-dependent degradation of TAB2/3

(2014) M.-M. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of NF-κB by TNF family cytokines

(2014) Matthew S. Hayden et al.   SEMINARS IN IMMUNOLOGY

Analysis of DNA methylation patterns associated with the gastric cancer genome

(2014) YI CHENG et al.   Oncology Letters

The E3-Ligase TRIM Family of Proteins Regulates Signaling Pathways Triggered by Innate Immune Pattern-Recognition Receptors

(2013) Gijs A. Versteeg et al.   IMMUNITY

E3 Ubiquitin Ligase Tripartite Motif 38 Negatively Regulates TLR-Mediated Immune Responses by Proteasomal Degradation of TNF Receptor-Associated Factor 6 in Macrophages

(2012) W. Zhao et al.   JOURNAL OF IMMUNOLOGY

Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks

(2012) Jonathan Woodsmith et al.   MOLECULAR & CELLULAR PROTEOMICS

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Nucleo-Cytoplasmic Trafficking of TRIM8, a Novel Oncogene, Is Involved in Positive Regulation of TNF Induced NF-κB Pathway

(2012) Dhanendra Tomar et al.   PLoS One

TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells

(2011) Dhanendra Tomar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Breaking the ‘harmony’ of TNF-α signaling for cancer treatment

(2011) S P Sasi et al.   ONCOGENE

Tripartite motif 8 (TRIM8) modulates TNF - and IL-1 -triggered NF- B activation by targeting TAK1 for K63-linked polyubiquitination

(2011) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse Aorta Smooth Muscle Cells Differentiate Into Lymphoid Tissue Organizer-Like Cells on Combined Tumor Necrosis Factor Receptor-1/Lymphotoxin β-Receptor NF-κB Signaling

(2010) Katharina Lötzer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

TRIM8 modulates STAT3 activity through negative regulation of PIAS3

(2010) F. Okumura et al.   JOURNAL OF CELL SCIENCE

Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

(2009) Yasushi Saeki et al.   EMBO JOURNAL

Lysine 63-linked Polyubiquitination of TAK1 at Lysine 158 Is Required for Tumor Necrosis Factor α- and Interleukin-1β-induced IKK/NF-κB and JNK/AP-1 Activation

(2009) Yihui Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pulsatile Stimulation Determines Timing and Specificity of NF- B-Dependent Transcription

(2009) L. Ashall et al.   SCIENCE

Signaling to NF- B: Regulation by Ubiquitination

(2009) I. E. Wertz et al.   Cold Spring Harbor Perspectives in Biology

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells

(2008) Ricardo Rajsbaum et al.   EUROPEAN JOURNAL OF IMMUNOLOGY