3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells
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Title
3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells
Authors
Keywords
human iPSC, chimeric antigen receptor T cells, CAR, 3D-organoid culture, pluripotent stem cell-artificial thymic organoid culture, PSC-ATO, off-the-shelf, immunotherapy
Journal
Cell Stem Cell
Volume 29, Issue 4, Pages 515-527.e8
Publisher
Elsevier BV
Online
2022-03-11
DOI
10.1016/j.stem.2022.02.009
References
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