TCR-induced FOXP3 expression by CD8+ T cells impairs their anti-tumor activity

Transcriptional regulatory network for the establishment of CD8+ T cell exhaustion

(2021) Wooseok Seo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Genetic Modification of CD8+ T Cells to Express EGFR: Potential Application for Adoptive T Cell Therapies

(2019) Teresa Lozano et al.   Frontiers in Immunology

Analysis of CD8+ Treg cells in patients with ovarian cancer: a possible mechanism for immune impairment

(2015) Shuping Zhang et al.   Cellular & Molecular Immunology

Myeloma cells act as tolerogenic antigen-presenting cells and induce regulatory T cellsin vitro

(2015) Maria Antonia Frassanito et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

The Transcription Factor NFAT Promotes Exhaustion of Activated CD8 + T Cells

(2015) Gustavo J. Martinez et al.   IMMUNITY

Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation

(2015) Teresa Lozano et al.   JOURNAL OF IMMUNOLOGY

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment

(2013) Joel Crespo et al.   CURRENT OPINION IN IMMUNOLOGY

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

Transcriptional insights into the CD8+ T cell response to infection and memory T cell formation

(2013) J Adam Best et al.   NATURE IMMUNOLOGY

Constitutive Nuclear Localization of NFAT in Foxp3+ Regulatory T Cells Independent of Calcineurin Activity

(2012) Q. Li et al.   JOURNAL OF IMMUNOLOGY

Transcription factor Foxp3 and its protein partners form a complex regulatory network

(2012) Dipayan Rudra et al.   NATURE IMMUNOLOGY

Sub-optimal CD4+ T-cell activation triggers autonomous TGF-β-dependent conversion to Foxp3+ regulatory T cells

(2011) Vanessa G. Oliveira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD8+Foxp3+ T cells share developmental and phenotypic features with classical CD4+Foxp3+ regulatory T cells but lack potent suppressive activity

(2011) Christian T. Mayer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells

(2011) Hozefa S. Bandukwala et al.   IMMUNITY

CD8+Foxp3+ tumor infiltrating lymphocytes accumulate in the context of an effective anti-tumor response

(2010) Dung T. Le et al.   INTERNATIONAL JOURNAL OF CANCER

A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo

(2009) T. Fehr et al.   BLOOD

Cutting Edge: Tumor-Specific CD8+ T Cells Infiltrating Prostatic Tumors Are Induced to Become Suppressor Cells

(2009) K. A. Shafer-Weaver et al.   JOURNAL OF IMMUNOLOGY

Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells

(2009) D. Getnet et al.   JOURNAL OF IMMUNOLOGY

Exuberated Numbers of Tumor-Specific T Cells Result in Tumor Escape

(2008) O. Goldberger et al.   CANCER RESEARCH

Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue

(2008) N Chaput et al.   GUT