Article
Medicine, General & Internal
Fausto Biancari, Antonio Salsano, Francesco Santini, Marisa De Feo, Magnus Dalen, Qiyao Zhang, Giuseppe Gatti, Enzo Mazzaro, Ilaria Franzese, Ciro Bancone, Marco Zanobini, Tuomas Tauriainen, Timo Makikallio, Matteo Saccocci, Alessandra Francica, Stefano Rosato, Zein El-Dean, Francesco Onorati, Giovanni Mariscalco
Summary: This study evaluated the risk of late mortality and major adverse cardiovascular and cerebral events in patients with prior percutaneous coronary intervention (PCI) who underwent coronary artery bypass grafting (CABG). The results showed that multiple prior PCIs increased the risk of myocardial infarction and repeat revascularization, but not mortality.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Valentino Bianco, Suresh Mulukutla, Edgar Aranda-Michel, Danny Chu, David Kaczorowski, Johannes Bonatti, Pyongsoo Yoon, Dustin Kliner, Catalin Toma, Yisi Wang, Steve Koscumb, Floyd Thoma, Forozan Navid, Derek Serna-Gallegos, Ibrahim Sultan
Summary: This study compares the outcomes of multiarterial grafting and percutaneous coronary intervention (PCI) in patients with multivessel coronary disease. It found that multiarterial grafting is associated with fewer adverse events, improved survival, and reduced hospital readmissions for appropriate patients.
ANNALS OF THORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
J. Hunter Mehaffey, J. W. Awori Hayanga, Mohammad Kawsara, Ankit Sakhuja, Christopher Mascio, J. Scott Rankin, Vinay Badhwar
Summary: Contemporary real-world data from Medicare patients with multivessel disease reveal that coronary artery bypass grafting (CABG) outcomes were superior to percutaneous coronary intervention (PCI), providing important longitudinal data to guide patient care and policy development.
ANNALS OF THORACIC SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Mahin R. Khan, Waleed T. Kayani, Jason Pelton, Ahmed Ansari, David Paniagua, Umair Khalid, Ali Denktas, Hameem U. Changezi, Ahmad Munir, Ernesto Jimenez, Mahboob Alam, Hani Jneid
Summary: In patients with left ventricular systolic dysfunction (LVD), coronary artery bypass surgery (CABG) was associated with lower long-term mortality and revascularization rates compared to percutaneous coronary intervention (PCI), but had a higher risk of upfront stroke. However, the majority of data were observational studies, emphasizing the need for randomized trials.
CARDIOVASCULAR DRUGS AND THERAPY
(2021)
Article
Surgery
Ryaan EL-Andari, Jeevan Nagendran, Yongzhe Hong, Imtiaz Ali, Jayan Nagendran
Summary: Comparison of referral patterns and outcomes between two centers in the same jurisdiction showed that more patients in Center A underwent PCI and fewer underwent CABG compared to Center B, even among patients with TVD. Regression analysis showed that Center B had a protective effect on mortality for TVD patients and those undergoing PCI, but not for CABG. Center A had increased 1-year mortality for all patients and those with TVD. The differences in outcomes can be attributed to contrasting referral practices and the discrepant rates of PCI and CABG between the centers.
Article
Medicine, General & Internal
Marc S. Sabatine, Brian A. Bergmark, Sabina A. Murphy, Patrick T. O'Gara, Peter K. Smith, Patrick W. Serruys, A. Pieter Kappetein, Seung-Jung Park, Duk-Woo Park, Evald H. Christiansen, Niels R. Holm, Per H. Nielsen, Gregg W. Stone, Joseph F. Sabik, Eugene Braunwald
Summary: A comparison of long-term outcomes between PCI with drug-eluting stents and CABG in patients with left main coronary artery disease showed no significant difference in 5-year all-cause mortality. However, differences were observed in rates of myocardial infarction, stroke, and repeat revascularisation, with higher risks associated with PCI. A Bayesian approach suggested a slight advantage favoring CABG in terms of mortality.
Article
Cardiac & Cardiovascular Systems
Shigetaka Kageyama, Patrick W. Serruys, Kai Ninomiya, Neil O'Leary, Shinichiro Masuda, Nozomi Kotoku, Antonio Colombo, Robert-Jan van Geuns, Milan Milojevic, Michael J. Mack, Alan Soo, Scot Garg, Yoshinobu Onuma, Piroze M. Davierwala, SYNTAX ExtendedSurvival Investigators
Summary: This study aimed to investigate the impact of on-pump and off-pump coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) on 10-year all-cause mortality. The results showed that after adjusting for major confounders, the 10-year mortality rate of on-pump CABG was significantly lower than that of PCI, while there was no significant difference between off-pump CABG and PCI.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2023)
Article
Multidisciplinary Sciences
Hristo Kirov, Tulio Caldonazo, Mohamed Rahouma, N. Bryce Robinson, Michelle Demetres, Patrick W. Serruys, Giuseppe Biondi-Zoccai, Mario Gaudino, Torsten Doenst
Summary: For the treatment of NSTE-ACS, CABG and PCI are associated with similar rates of long-term mortality and myocardial infarction. CABG is associated with lower rates of long-term MACE and re-revascularization.
SCIENTIFIC REPORTS
(2022)
Review
Cardiac & Cardiovascular Systems
Nicholas W. S. Chew, Jin Hean Koh, Cheng Han Ng, Darren Jun Hao Tan, Jie Ning Yong, Chaoxing Lin, Oliver Zi-Hern Lim, Yip Han Chin, Denzel Ming Wei Lim, Koo Hui Chan, Poay-Huan Loh, Adrian Low, Chi-Hang Lee, Huay-Cheem Tan, Mark Chan
Summary: This study conducted a two-stage meta-analysis using reconstructed individual patient data to compare long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for patients with multivessel disease (MVD) without left main (LM) involvement. The results showed that CABG had a lower cumulative all-cause mortality compared to PCI for MVD patients without LM involvement. However, in patients with moderate to high SYNTAX score, PCI had a significantly higher 10-year all-cause mortality compared to CABG.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Alistair G. Royse, Rinaldo Bellomo, Colin F. Royse, Sandy Clarke-Errey, Stuart Boggett, Thomas Kelly, Hugh S. Paterson
Summary: Two different surgical methods for total arterial coronary revascularization of three coronary territory disease showed no significant difference in survival rates among younger patients.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Garry W. Hamilton, Diem Dinh, Julian Yeoh, Angela L. Brennan, Jordan Fulcher, Anoop N. Koshy, Matias B. Yudi, Christopher M. Reid, David L. Hare, Melanie Freeman, Dion Stub, William Chen, Stephen J. Duffy, Andrew Ajani, Jaishankar Raman, Omar Farouque, David J. Clark
Summary: This study reports the characteristics of arterial graft stenoses and evaluates the feasibility of radial artery percutaneous coronary intervention (PCI). The results show that patients undergoing radial artery PCI had earlier presentation, less frequent acute coronary syndrome, and more common intervention at the ostial or distal anastomosis compared with saphenous vein graft PCI. Patients undergoing radial artery PCI were more likely to have diabetes, peripheral vascular disease, and non-ST-segment elevation myocardial infarction compared with those undergoing native PCI.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Multidisciplinary Sciences
Hiroki Watanabe, Ko Yamamoto, Hiroki Shiomi, Takeshi Morimoto, Eri Kato, Yukiko Matsumura, Kenji Nakatsuma, Yasuaki Takeji, Hidenori Yaku, Erika Yamamoto, Yugo Yamashita, Yusuke Yoshikawa, Masayuki Fuki, Kyohei Yamaji, Natsuhiko Ehara, Hiroki Sakamoto, Kazuaki Imada, Takeshi Tada, Ryoji Taniguchi, Ryusuke Nishikawa, Tomohisa Tada, Takashi Uegaito, Tatsuya Ogawa, Miho Yamada, Teruki Takeda, Hiroshi Eizawa, Nobushige Tamura, Keiichi Tambara, Satoru Suwa, Manabu Shirotani, Toshihiro Tamura, Moriaki Inoko, Junichiro Nishizawa, Masahiro Natsuaki, Hiroshi Sakai, Takashi Yamamoto, Naoki Kanemitsu, Nobuhisa Ohno, Katsuhisa Ishii, Akira Marui, Hiroshi Tsuneyoshi, Yasuhiko Terai, Shogo Nakayama, Kazuhiro Yamazaki, Mamoru Takahashi, Takashi Tamura, Jiro Esaki, Shinji Miki, Tomoya Onodera, Hiroshi Mabuchi, Yutaka Furukawa, Masaru Tanaka, Tatsuhiko Komiya, Yoshiharu Soga, Michiya Hanyu, Kenji Ando, Kazushige Kadota, Kenji Minatoya, Yoshihisa Nakagawa, Takeshi Kimura
Summary: This study compared the effectiveness of percutaneous coronary intervention (PCI) using new-generation drug-eluting stents (DES) with coronary artery bypass grafting (CABG) in patients with multi-vessel coronary artery disease. The results showed that, compared to CABG, PCI for coronary revascularization was associated with an increased long-term risk of major cardiovascular events.
Article
Cardiac & Cardiovascular Systems
Shutong Dong, Zehao Zhao, Xin Huang, Meishi Ma, Zhiqiang Yang, Chu Fan, Hongya Han, Zhijian Wang, Dongmei Shi, Yujie Zhou
Summary: This study suggests that the TyG index is independently associated with poor prognosis in ACS patients with prior CABG undergoing PCI, and may serve as a valid indicator for predicting adverse outcomes.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Valentino Bianco, Arman Kilic, Edgar Aranda-Michel, Derek Serna-Gallegos, Francis Ferdinand, Courtenay Dunn-Lewis, Yisi Wang, Floyd Thoma, Forozan Navid, Ibrahim Sultan
Summary: The aim of this study was to provide risk-adjusted outcomes for complete revascularization. Complete surgical revascularization of all vessels in patients with multivessel coronary artery disease is associated with fewer major adverse events. Incomplete revascularization of nonmain-branch vessels is not associated with survival or major adverse cardiac and cerebrovascular events.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Nicholas W. S. Chew, Chen-Han Ng, Gwyneth Kong, Keng-Siang Lee, Darren J. H. Tan, Oliver Zi-Hern Lim, Yip Han Chin, Bee Choo Tai, Tianyuan Gu, Seung-Jung Park, Duk-Woo Park, Marie-Claude Morice, Theodoros Kofidis, James W. L. Yip, Poay-Huan Loh, Koo-Hui Chan, Adrian F. Low, Chi-Hang Lee, Tiong-Cheng Yeo, Huay-Cheem Tan, Mark Y. Chan
Summary: This study compared percutaneous coronary intervention (PCI) with drug-eluting stents and coronary artery bypass grafting (CABG) in the treatment of left main coronary artery disease (LMCAD) and found no statistically significant difference in cumulative 10-year all-cause mortality between the two groups. However, PCI had a higher rate of unplanned revascularization within 5 years.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Craig M. Jarrett, Marc Pelletier, Yasir Abu-Omar, Cristian Baeza, Yakov Elgudin, Alan Markowitz, Pablo Ruda Vega, Ovidiu Dressler, Arie Pieter Kappetein, Patrick W. Serruys, Gregg W. Stone, Joseph F. Sabik
Summary: The study compared the outcomes of coronary artery bypass grafting (CABG) with endoscopic vein harvest (EVH) vs open vein harvest (OVH). The patients with different vein harvesting methods had different rates of ischemia-driven revascularization at 5 years. No significant differences were found in other endpoints, such as graft stenosis or occlusion, death, stroke, myocardial infarction, bleeding, blood product transfusion, major arrhythmia, and infection.
ANNALS OF THORACIC SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Vincenzo Tufaro, Patrick Washington Serruys, Lorenz Raber, Martin Richard Bennett, Ryo Torii, Sophie Zhaotao Gu, Yoshinobu Onuma, Anthony Mathur, Andreas Baumbach, Christos Vasileios Bourantas
Summary: Intravascular imaging plays an important role in assessing the effectiveness of drug therapies targeting atherosclerosis. Serial intravascular ultrasound, optical coherence tomography, or near-infrared spectroscopy-intravascular ultrasound studies allow for evaluation of the impact of different treatments on plaque burden and morphology. However, established intravascular imaging surrogate endpoints have limited efficacy in predicting the prognostic value of these therapies, necessitating the development of alternative imaging endpoints based on multimodality/hybrid intravascular imaging.
CARDIOVASCULAR RESEARCH
(2023)
Letter
Cardiac & Cardiovascular Systems
Hesham Elzomor, Hendrik Wienemann, Tanja K. Rudolph, Matti Adam, Osama Soliman, Ashok Seth, Martin B. Leon, Hans R. Figulla, Patrick W. Serruys
CARDIOVASCULAR REVASCULARIZATION MEDICINE
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Murat Cap, Ryo Torii, Yoshinobu Onuma, Rob Krams, Martin R. Bennett, Peter H. Stone, Patrick W. Serruys, Christos V. Bourantas
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Masafumi Ono, Shigetaka Kageyama, Neil O'Leary, Mohammed S. El-Kurdi, Jochen Reinoehl, Eric Solien, Richard W. Bianco, Mirko Doss, Bart Meuris, Renu Virmani, Martijn Cox, Yoshinobu Onuma, Patrick W. Serruys
Summary: This study demonstrates the feasibility and effectiveness of a novel biorestorative graft in an ovine coronary artery bypass graft model, suggesting its potential as an alternative to saphenous vein grafts. These findings could pave the way for the first-in-man trial of using this new material for coronary artery bypass graft patients who struggle with harvesting SVGs.
JACC-BASIC TO TRANSLATIONAL SCIENCE
(2023)
Letter
Cardiac & Cardiovascular Systems
Shigetaka Kageyama, Yoshinobu Onuma, Scot Garg, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Sneha S. Jain, Ditian Li, Ovidiu Dressler, Lak Kotinkaduwa, Patrick W. Serruys, A. Pieter Kappetein, Joseph F. Sabik, Marie-Claude Morice, John Puskas, David E. Kandzari, Dimitri Karmpaliotis, Nicholas J. Lembo, W. Morris Brown, Adrian P. Banning, Gregg W. Stone
Summary: This study assessed the association between periprocedural major adverse events (MAE) and subsequent mortality after percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for left main coronary artery revascularization. The study found that nonfatal periprocedural MAE strongly predicted both early and late mortality after both PCI and CABG.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Review
Cardiac & Cardiovascular Systems
Mahmoud Abdelshafy, Patrick W. Serruys, Tsung-Ying Tsai, Pruthvi Chenniganahosahalli Revaiah, Scot Garg, Jean-Paul Aben, Carl J. Schultz, Mohammad Abdelghani, Pim A. L. Tonino, Yosuke Miyazaki, Marcel C. M. Rutten, Martijn Cox, Cherif Sahyoun, Justin Teng, Hiroki Tateishi, Mohamed Abdel-Wahab, Nicolo Piazza, Michele Pighi, Rodrigo Modolo, Martijn van Mourik, Joanna Wykrzykowska, Robbert J. de Winter, Pedro A. Lemos, Fabio S. de Brito Jr, Hideyuki Kawashima, Lars Sondergaard, Liesbeth Rosseel, Rutao Wang, Chao Gao, Ling Tao, Andreas Rueck, Won-Keun Kim, Niels van Royen, Christian J. Terkelsen, Henrik Nissen, Matti Adam, Tanja K. Rudolph, Hendrik Wienemann, Ryo Torii, Franz Josef Neuman, Simon Schoechlin, Mao Chen, Ahmed Elkoumy, Hesham Elzomor, Ignacio J. Amat-Santos, Darren Mylotte, Osama Soliman, Yoshinobu Onuma
Summary: Paravalvular leak (PVL) is a drawback in transcatheter valve replacement (TAVR), and a readily applicable method to accurately quantify PVL (aortography) is appealing to operators. The regurgitation fraction (RF) is determined by the ratio between the time-density curves in the aorta and left ventricular outflow tract (LVOT-AR). This technique has been validated in mock circulation and tested in animal models, and compared with echocardiography and cardiac magnetic resonance imaging in clinical settings.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Dan Nguyen, Nobuhiro Ikemura, Khaja Chinnakondepalli, Elizabeth Magnuson, Adam Christopher Salisbury, Patrick W. Serruys, David J. Cohen, Suzanne Arnold
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Hesham El Zomor, Hendrik Wienemann, Matti Adam, Tanja Rudolph, Ahmed Elkoumy, Mahmoud Abdelshafy, Pruthvi Chenniganahosahalli Revaiah, Patrick W. Serruys, Osama Soliman
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Shinichiro Masuda, Patrick W. Serruys, Shigetaka Kageyama, Nozomi Kotoku, Kai Ninomiya, Scot Garg, Alan Soo, Marie-Angele Morel, John D. Puskas, Jagat Narula, Ulrich Schneider, Torsten Doenst, Kaoru Tanaka, Johan de Mey, Mark La Meir, Antonio L. Bartorelli, Saima Mushtaq, Giulio Pompilio, Daniele Andreini, Yoshinobu Onuma
Summary: This study compared treatment recommendations based on the SYNTAX score 2020 derived from coronary computed tomography angiography (CCTA) and invasive coronary angiography (ICA). The results showed moderate to substantial agreement between the anatomical SYNTAX scores derived from CCTA and ICA, suggesting that CCTA could be used as an alternative to ICA when making decisions regarding the modality of revascularization.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Nozomi Kotoku, Daixin Ding, Kai Ninomiya, Neil O' Leary, William Wijns, Shengxian Tu, Nicolo Piazza, Yoshinobu Onuma, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Kai Ninomiya, Patrick Serruys, Shinichiro Masuda, Jiayue Huang, Ding Daixin, Nozomi Kotoku, Shigetaka Kageyama, Manish Doshi, William Wijns, Shengxian Tu, Faisal Sharif, Bernardo Cortese, Sandeep Basavarajaiah, Bernhard Reimers, Antonio Colombo, Yoshinobu Onuma
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Yoshinobu Onuma, Shinichiro Masuda, Takashi Muramatsu, Yuki Ishibashi, Ken Kozuma, Hideyuki Kawashima, Gaku Nakazawa, Kuniaki Takahashi, Kengo Tanabe, Norihiro Kogame, Masato Nakamura, Taku Asano, Takayuki Okamura, Yosuke Miyazaki, Hiroki Tateishi, Yukio Ozaki, Shimpei Nakatani, Yuki Katagiri, Yoshihiro Morino, Kai Ninomiya, Shigetaka Kageyama, Nozomi Kotoku, Patricia O. Guimaraes, Pedro A. Lemos, Patrick W. Serruys
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Cardiac & Cardiovascular Systems
Patrick W. Serruys, Nozomi Kotoku, Bjarne L. Norgaard, Scot Garg, Koen Nieman, Marc R. Dweck, Jeroen J. Bax, Juhani Knuuti, Jagat Narula, Divaka Perera, Charles A. Taylor, Jonathon A. Leipsic, Edward D. Nicol, Nicolo Piazza, Carl J. Schultz, Kakuya Kitagawa, Bernard De Bruyne, Carlos Collet, Kaoru Tanaka, Saima Mushtaq, Marta Belmonte, Darius Dudek, Adriana Zlahoda-Huzior, Shengxian Tu, William Wijns, Faisal Sharif, Matthew J. Budoff, Johan de Mey, Daniele Andreini, Yoshinobu Onuma
Summary: Coronary computed tomographic angiography (CCTA) has become the preferred investigation for determining the presence and haemodynamic significance of coronary artery disease. It can rule out atherosclerosis or detect subclinical plaque in patients without significant epicardial obstruction, and provide risk classification. For ischaemic non-obstructive coronary arteries, non-invasive imaging, including CCTA, is also expected. In patients with significant epicardial obstruction, CCTA can assist in planning revascularisation by determining disease complexity, vessel size, lesion length, tissue composition of the atherosclerotic plaque, and the best fluoroscopic viewing angle.