Common founder BRCA2 pathogenic variants and breast cancer characteristics in Ethiopian Jews

Recurring pathogenic variants in the BRCA2 gene in the Ethiopian Jewish population. Founder mutations?

(2022) Mark D. Ludman et al.   Familial Cancer

Breast cancer in sub-Saharan Africa: The current state and uncertain future

(2021) Claudia A Anyigba et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer

(2021) Andrew N.J. Tutt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effect and Safety of Therapeutic Regimens for Patients With Germline BRCA Mutation-Associated Breast Cancer: A Network Meta-Analysis

(2021) Ying Jiang et al.   Frontiers in Oncology

“High-Risk Breast Cancer Screening in BRCA1/2 Carriers Leads to Early Detection and Improved Survival After a Breast Cancer Diagnosis”

(2021) Shay Shraga et al.   Frontiers in Oncology

Pioneering Informed Consent for Return of Research Results to Breast Cancer Patients Facing Barriers to Implementation of Genomic Medicine: The Kenyan BRCA1/2 Testing Experience Using Whole Exome Sequencing

(2020) Rispah Torrorey-Sawe et al.   Frontiers in Genetics

Presymptomatic Awareness of Germline Pathogenic BRCA Variants and Associated Outcomes in Women With Breast Cancer

(2020) Tal Hadar et al.   JAMA Oncology

Economic Evaluation of Population-Based BRCA1/BRCA2 Mutation Testing across Multiple Countries and Health Systems

(2020) Ranjit Manchanda et al.   Cancers

Racial Disparities in Triple Negative Breast Cancer: A Review of the Role of Biologic and Non-biologic Factors

(2020) Om Prakash et al.   Frontiers in Public Health

Improving early detection of breast cancer in sub-Saharan Africa: why mammography may not be the way forward

(2019) Eleanor Black et al.   Globalization and Health

BRCA1 and BRCA2 Pathogenic Sequence Variants in Women of African Origin or Ancestry

(2019) Tara M. Friebel et al.   HUMAN MUTATION

Social determinants of breast cancer risk, stage, and survival

(2019) Steven S. Coughlin   BREAST CANCER RESEARCH AND TREATMENT

Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women

(2019) Heidi D. Nelson et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa

(2019) Deepti Gurdasani et al.   CELL

Breast cancer surveillance for BRCA1/2 mutation carriers – is “early detection” early enough?

(2019) Rinat Bernstein-Molho et al.   BREAST

The yield of full BRCA1/2 genotyping in Israeli high-risk breast/ovarian cancer patients who do not carry the predominant mutations

(2018) Inbal Barnes-Kedar et al.   BREAST CANCER RESEARCH AND TREATMENT

Inherited Breast Cancer in Nigerian Women

(2018) Yonglan Zheng et al.   JOURNAL OF CLINICAL ONCOLOGY

Essential Role of BRCA2 in Ovarian Development and Function

(2018) Ariella Weinberg-Shukron et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features

(2018) Jason J. Pitt et al.   Nature Communications

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

(2017) Karoline B. Kuchenbaecker et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels

(2017) Holly LaDuca et al.   PLoS One

Incorporating truncating variants in PALB2, CHEK2 and ATM into the BOADICEA breast cancer risk model

(2016) Andrew J. Lee et al.   GENETICS IN MEDICINE

Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians

(2015) Luca Pagani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Population-based screening for breast and ovarian cancer risk due toBRCA1andBRCA2

(2014) Efrat Gabai-Kapara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recurrent germline mutations in BRCA1 and BRCA2 genes in high risk families in Israel

(2012) Yael Laitman et al.   BREAST CANCER RESEARCH AND TREATMENT

North African Jewish and non-Jewish populations form distinctive, orthogonal clusters

(2012) C. L. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differences in pathological and clinical features of breast cancer in Arab as compared to Jewish women in Northern Israel

(2011) Jamal Zidan et al.   INTERNATIONAL JOURNAL OF CANCER