TIP60 buffers acute stress response and depressive behaviour by controlling PPARγ-mediated transcription

Adiponectin Mediates the Protection of H2S Against Chronic Restraint Stress-Induced Cognitive Impairment via Attenuating Hippocampal Damage

(2021) Qiong-Yan Tang et al.   Frontiers in Behavioral Neuroscience

Valproic acid administration exerts protective effects against stress-related anhedonia in rats

(2020) Mina Goudarzi et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Acute Stress Enhances Associative Learning via Dopamine Signaling in the Ventral Lateral Striatum

(2020) Claire E. Stelly et al.   JOURNAL OF NEUROSCIENCE

Reduction of NgR in perforant path decreases amyloid-β peptide production and ameliorates synaptic and cognitive deficits in APP/PS1 mice

(2020) Rong Jiang et al.   Alzheimers Research & Therapy

Nuclear Receptors as Regulators of Pituitary Corticotroph Pro-Opiomelanocortin Transcription

(2020) Dongyun Zhang et al.   Cells

TIP60 in Aging and Neurodegeneration

(2020) Zhiquan Li et al.   AGEING RESEARCH REVIEWS

Metabolic Roles of Androgen Receptor and Tip60 in Androgen-Dependent Prostate Cancer

(2020) Kah Ni Tan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PPAR-γ Is Critical for HDAC3-Mediated Control of Oligodendrocyte Progenitor Cell Proliferation and Differentiation after Focal Demyelination

(2020) Lingzhi Ding et al.   MOLECULAR NEUROBIOLOGY

Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases

(2020) Mariah Beaver et al.   Scientific Reports

Differential modulation of GR signaling and HDACs in the development of resilient/vulnerable phenotype and antidepressant-like response of vorinostat

(2020) Athira K V et al.   PSYCHONEUROENDOCRINOLOGY

Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ

(2019) Zhi-hao Zhang et al.   ACTA PHARMACOLOGICA SINICA

Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence

(2019) Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PPARγ and Cognitive Performance

(2019) Michele d’Angelo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TIP60/KAT5 is required for neuronal viability in hippocampal CA1

(2019) Inga Urban et al.   Scientific Reports

Losartan modulates brain inflammation and improves mood disorders and memory impairment induced by innate immune activation: The role of PPAR-γ activation

(2019) Hossein Salmani et al.   CYTOKINE

Hippocampal stimulation promotes intracellular Tip60 dynamics with concomitant genome reorganization and synaptic gene activation

(2019) Ashley Karnay et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer

(2018) Xiao Fang et al.   EXPERIMENTAL CELL RESEARCH

Tip60: updates

(2018) Ahmed H. Ghobashi et al.   JOURNAL OF APPLIED GENETICS

Dorsal CA1 interneurons contribute to acute stress-induced spatial memory deficits

(2018) Jing-Ying Yu et al.   NEUROPHARMACOLOGY

Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response

(2018) Benedetto Daniele Giaimo et al.   NUCLEIC ACIDS RESEARCH

Inhibition of Tip60 Reduces Lytic and Latent Gene Expression of Kaposi’s Sarcoma-Associated Herpes Virus (KSHV) and Proliferation of KSHV-Infected Tumor Cells

(2018) Sydney Simpson et al.   Frontiers in Microbiology

Long-term social isolation inhibits autophagy activation, induces postsynaptic dysfunctions and impairs spatial memory

(2018) Bin Wang et al.   EXPERIMENTAL NEUROLOGY

Mechanisms underlying prelimbic prefrontal cortex mGlu3/mGlu5-dependent plasticity and reversal learning deficits following acute stress

(2018) Max E. Joffe et al.   NEUROPHARMACOLOGY

TRPV1 Regulates Stress Responses through HDAC2

(2017) Sung Eun Wang et al.   Cell Reports

Antidepressant-like activity of sildenafil following acute and subchronic treatment in the forced swim test in mice: effects of restraint stress and monoamine depletion

(2016) Katarzyna Socała et al.   METABOLIC BRAIN DISEASE

Role of the adipose PPARγ-adiponectin axis in susceptibility to stress and depression/anxiety-related behaviors

(2016) M Guo et al.   MOLECULAR PSYCHIATRY

Regulation of ER stress-induced autophagy by GSK3β-TIP60-ULK1 pathway

(2016) Tiejian Nie et al.   Cell Death & Disease

Dopamine D1 receptors are responsible for stress-induced emotional memory deficit in mice

(2016) Yongfu Wang et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

The chromodomain-containing histone acetyltransferase TIP60 acts as a code reader, recognizing the epigenetic codes for initiating transcription

(2015) Chul-Hong Kim et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

PPARγ agonists regulate bidirectional transport of amyloid-β across the blood-brain barrier and hippocampus plasticity indb/dbmice

(2015) Hao Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Acetylation of Histone H2AX at Lys 5 by the TIP60 Histone Acetyltransferase Complex Is Essential for the Dynamic Binding of NBS1 to Damaged Chromatin

(2015) Masae Ikura et al.   MOLECULAR AND CELLULAR BIOLOGY

Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity

(2015) Carla Nasca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prereproductive stress in adolescent female rats affects behavior and corticosterone levels in second-generation offspring

(2015) Hiba Zaidan et al.   PSYCHONEUROENDOCRINOLOGY

A bivalent role of TIP60 histone acetyl transferase in human cancer

(2015) Gaëlle Judes et al.   Epigenomics

The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60

(2015) Hongmei Cui et al.   Nature Communications

Involvement of GPR50 polymorphisms in depression: independent replication in a prospective elderly cohort

(2015) Joanne Ryan et al.   Brain and Behavior

Regulation of Histone Acetyltransferase TIP60 Function by Histone Deacetylase 3

(2014) Jingjie Yi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coactivator MYST1 Regulates Nuclear Factor-κB and Androgen Receptor Functions During Proliferation of Prostate Cancer Cells

(2014) Anbalagan Jaganathan et al.   MOLECULAR ENDOCRINOLOGY

Lamotrigine attenuates deficits in synaptic plasticity and accumulation of amyloid plaques in APP/PS1 transgenic mice

(2014) Mao-Ying Zhang et al.   NEUROBIOLOGY OF AGING

Acute Restraint Stress Impairs Induction of Long-Term Potentiation by Activating GSK-3β

(2014) Yu Jin et al.   NEUROCHEMICAL RESEARCH

Histone deacetylases in memory and cognition

(2014) J. Penney et al.   Science Signaling

Acute stress causes rapid synaptic insertion of Ca2+-permeable AMPA receptors to facilitate long-term potentiation in the hippocampus

(2013) Garry Whitehead et al.   BRAIN

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Restraint Stress in Rats Alters Gene Transcription and Protein Translation in the Hippocampus

(2012) Petra Sántha et al.   NEUROCHEMICAL RESEARCH

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

(2012) S.-Y. Lin et al.   SCIENCE

Antidepressant-like effect of pioglitazone in the forced swimming test in mice: The role of PPAR-gamma receptor and nitric oxide pathway

(2011) Mohammad Salehi Sadaghiani et al.   BEHAVIOURAL BRAIN RESEARCH

Notch Signaling Modulates Sleep Homeostasis and Learning after Sleep Deprivation in Drosophila

(2011) Laurent Seugnet et al.   CURRENT BIOLOGY

Quality of Life in Postmenopausal Women: The Impact of Depressive and Anxiety Disorders

(2011) Faruk Uguz et al.   INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE

Differential Effectiveness of Antipsychotics in Borderline Personality Disorder

(2011) Theo J.M. Ingenhoven et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Microarray Analysis Uncovers a Role for Tip60 in Nervous System Function and General Metabolism

(2011) Meridith Lorbeck et al.   PLoS One

GPR50 Interacts with TIP60 to Modulate Glucocorticoid Receptor Signalling

(2011) Jian Li et al.   PLoS One

Antidepressant-like effects of rosiglitazone, a PPARγ agonist, in the rat forced swim and mouse tail suspension tests

(2009) Amany Ali Eissa Ahmed et al.   BEHAVIOURAL PHARMACOLOGY

Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory

(2009) E. Y. Yuen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estradiol and the relationship between dendritic spines, NR2B containing NMDA receptors, and the magnitude of long-term potentiation at hippocampal CA3–CA1 synapses

(2009) Caroline C. Smith et al.   PSYCHONEUROENDOCRINOLOGY

Cross-Talk between PPARs and the Partners of RXR: A Molecular Perspective

(2009) Lap Shu Alan Chan et al.   PPAR Research

Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells

(2008) Rohita Sharma et al.   JOURNAL OF PINEAL RESEARCH

The Adipogenic Acetyltransferase Tip60 Targets Activation Function 1 of Peroxisome Proliferator-Activated Receptor γ

(2007) Olivier van Beekum et al.   ENDOCRINOLOGY