Markers of rejection of a lung allograft: state of the art

Lung microbiota predict chronic rejection in healthy lung transplant recipients: a prospective cohort study

(2021) Michael P Combs et al.   Lancet Respiratory Medicine

Donor-derived Cell-free DNA in Solid Organ Transplant Diagnostics

(2021) Ashish Kataria et al.   TRANSPLANTATION

Importance of the preoperative prognostic nutritional index score as a predictor of chronic lung allograft dysfunction after lung transplantation: a Japanese single-institution study

(2021) Takashi Kanou et al.   SURGERY TODAY

Airway Telomere Length in Lung Transplant Recipients

(2021) John A. Mackintosh et al.   Frontiers in Immunology

Regulatory and Effector Cell Disequilibrium in Patients with Acute Cellular Rejection and Chronic Lung Allograft Dysfunction after Lung Transplantation: Comparison of Peripheral and Alveolar Distribution

(2021) Laura Bergantini et al.   Cells

A virtual crossmatch-based strategy for perioperative desensitisation in lung transplant recipients with preformed donor-specific antibodies: 3-year outcome

(2021) Francois Parquin et al.   EUROPEAN RESPIRATORY JOURNAL

Impacts of single nucleotide polymorphisms in Fc gamma receptor IIA ( rs1801274 ) on lung transplant outcomes among Japanese lung transplant recipients

(2021) Hidenao Kayawake et al.   TRANSPLANT INTERNATIONAL

Emerging biomarkers in chronic lung allograft dysfunction

(2020) Osnat Shtraichman et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Dynamics of human monocytes and airway macrophages during healthy aging and after transplant

(2020) Adam J. Byrne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Increased frequency of CD4 + CD25 high CD127 low T cells early after lung transplant is associated with improved graft survival – a retrospective study

(2020) Fabio Ius et al.   TRANSPLANT INTERNATIONAL

Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation – Consensus for the Banff Human Organ Transplant (B‐HOT) gene panel and open source multicenter validation

(2020) M. Mengel et al.   AMERICAN JOURNAL OF TRANSPLANTATION

International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation

(2020) Tereza Martinu et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis

(2020) Taylor S. Adams et al.   Science Advances

Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

(2020) Arun C. Habermann et al.   Science Advances

Global Proteomics Analysis of Circulating Extracellular Vesicles Isolated from Lung Transplant Recipients

(2020) Sandhya Bansal et al.   ACS Omega

Donor-specific antibody characteristics, including persistence and complement-binding capacity, increase risk for chronic lung allograft dysfunction

(2020) Carlo J. Iasella et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The Autotaxin-Lysophosphatidic-Acid Pathway Mediates Mesenchymal Cell Recruitment and Fibrotic Contraction in Lung Transplant Fibrosis

(2020) Kenneth Andrew Sinclair et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

More than a Genetic Code: Epigenetics of Lung Fibrosis

(2020) Krystian Bartczak et al.   Molecular Diagnosis & Therapy

Mathematical modeling of peripheral blood neutrophil kinetics to predict CLAD after lung transplantation

(2020) Benjamin Coiffard et al.   TRANSPLANT IMMUNOLOGY

Decline in Club Cell Secretory Proteins, Exosomes Induction and Immune Responses to Lung Self-antigens, Kα1 Tubulin and Collagen V, Leading to Chronic Rejection after Human Lung Transplantation

(2020) Yoshihiro Itabashi et al.   TRANSPLANTATION

A molecular cell atlas of the human lung from single-cell RNA sequencing

(2020) Kyle J. Travaglini et al.   NATURE

Peripheral Blood Eosinophilia Is Associated with Poor Outcome Post-Lung Transplantation

(2020) Janne Kaes et al.   Cells

Unveiling the Role of DNA Methylation in Kidney Transplantation: Novel Perspectives toward Biomarker Identification

(2019) Antonella Agodi et al.   Biomed Research International

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

(2019) Mairead L. Bermingham et al.   EBioMedicine

Donor-derived cell-free DNA predicts allograft failure and mortality after lung transplantation

(2019) Sean Agbor-Enoh et al.   EBioMedicine

Prevalence of antibodies to lung self-antigens (Kα1 tubulin and collagen V) and donor specific antibodies to HLA in lung transplant recipients and implications for lung transplant outcomes: Single center experience

(2019) Usha Rao et al.   TRANSPLANT IMMUNOLOGY

The role of donor-derived exosomes in lung allograft rejection

(2019) Ranjithkumar Ravichandran et al.   HUMAN IMMUNOLOGY

Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course

(2019) Herman T. den Dekker et al.   EUROPEAN RESPIRATORY JOURNAL

Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants

(2019) Aparna C. Swaminathan et al.   CHEST

Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection

(2019) S. Samuel Weigt et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Chronic lung allograft dysfunction: Definition and update of restrictive allograft syndrome―A consensus report from the Pulmonary Council of the ISHLT

(2019) Allan R. Glanville et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment―A consensus report from the Pulmonary Council of the ISHLT

(2019) Geert M. Verleden et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis

(2019) Peter D. Fransquet et al.   Clinical Epigenetics

Cell-Free DNA and CXCL10 Derived from Bronchoalveolar Lavage Predict Lung Transplant Survival

(2019) Joshua Yang et al.   Journal of Clinical Medicine

Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis

(2019) Christina Morse et al.   EUROPEAN RESPIRATORY JOURNAL

Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells

(2019) Christopher Andrew Tibbitt et al.   IMMUNITY

FCGR3A and FCGR2A Genotypes Differentially Impact Allograft Rejection and Patients' Survival After Lung Transplant

(2019) Pascale Paul et al.   Frontiers in Immunology

Early Identification of Chronic Lung Allograft Dysfunction: The Need of Biomarkers

(2019) Adrien Tissot et al.   Frontiers in Immunology

Rate of normal lung function decline in ageing adults: a systematic review of prospective cohort studies

(2019) Elizabeth T Thomas et al.   BMJ Open

The role of exosomes in allograft immunity

(2018) Sandhya Bansal et al.   CELLULAR IMMUNOLOGY

Role of C1q-binding anti-HLA antibodies as a predictor of lung allograft outcome

(2018) O Brugière et al.   EUROPEAN RESPIRATORY JOURNAL

High circulating CD4 + CD25 hi FOXP3 + T-cell sub-population early after lung transplantation is associated with development of bronchiolitis obliterans syndrome

(2018) Maxim Durand et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Circulating Exosomes with Distinct Properties during Chronic Lung Allograft Rejection

(2018) Muthukumar Gunasekaran et al.   JOURNAL OF IMMUNOLOGY

Chronic Lung Allograft Dysfunction: Evolving Concepts and Therapies

(2018) Ariss DerHovanessian et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Impact of human leukocyte antigen mismatch on lung transplant outcome†

(2018) Yoshito Yamada et al.   Interactive Cardiovascular and Thoracic Surgery

Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome

(2018) Richard Danger et al.   Frontiers in Immunology

Where the Chromosome Ends: Telomeres and CMV Risk in Lung Transplant Recipients

(2018) John R Greenland   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Association of methacholine challenge test with diagnosis of chronic lung allograft dysfunction in lung transplant patients

(2018) Atif S. Siddiqui et al.   CLINICAL TRANSPLANTATION

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-Fifth Adult Lung and Heart–Lung Transplant Report—2018; Focus Theme: Multiorgan Transplantation

(2018) Daniel C. Chambers et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Characteristics, properties, and potential applications of circulating cell-free dna in clinical diagnostics: a focus on transplantation

(2018) Karen Sherwood et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The common rejection module in chronic rejection post lung transplantation

(2018) Annelore Sacreas et al.   PLoS One

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

(2018) Paul A Reyfman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease

(2018) Joshua Moss et al.   Nature Communications

Donor-specific and -nonspecific HLA antibodies and outcome post lung transplantation

(2017) Stijn E. Verleden et al.   EUROPEAN RESPIRATORY JOURNAL

Telomere length in patients with pulmonary fibrosis associated with chronic lung allograft dysfunction and post–lung transplantation survival

(2017) Chad A. Newton et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Cell-Free DNA and Active Rejection in Kidney Allografts

(2017) Roy D. Bloom et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Short lung transplant donor telomere length is associated with decreased CLAD-free survival

(2017) Hilary E Faust et al.   THORAX

Exosomes

(2017) Adrian E. Morelli   TRANSPLANTATION

Analysis of long term CD4+CD25highCD127- T-reg cells kinetics in peripheral blood of lung transplant recipients

(2017) Davide Piloni et al.   BMC Pulmonary Medicine

The epigenetic promise to improve prognosis of heart failure and heart transplantation

(2017) Chiara Sabia et al.   Transplantation Reviews

De NovoDQ Donor-Specific Antibodies Are Associated with Chronic Lung Allograft Dysfunction after Lung Transplantation

(2016) Jussi M. Tikkanen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Donor-Derived Exosomes With Lung Self-Antigens in Human Lung Allograft Rejection

(2016) M. Gunasekaran et al.   AMERICAN JOURNAL OF TRANSPLANTATION

De-novo donor-specific anti-HLA antibodies 30 days after lung transplantation are associated with a worse outcome

(2016) Jérôme Le Pavec et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Influence of human leukocyte antigen mismatching on bronchiolitis obliterans syndrome in lung transplantation

(2016) Don Hayes et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Association of Donor and Recipient Telomere Length with Clinical Outcomes following Lung Transplantation

(2016) Andrew M. Courtwright et al.   PLoS One

Humoral immunity in phenotypes of chronic lung allograft dysfunction: A broncho-alveolar lavage fluid analysis

(2016) Elly Vandermeulen et al.   TRANSPLANT IMMUNOLOGY

Chronic Lung Allograft Dysfunction

(2016) Pierre-Joseph Royer et al.   TRANSPLANTATION

Therapeutic Targeting of Telomerase

(2016) Kathrin Jäger et al.   Genes

HLA-E⁎01:03 Allele in Lung Transplant Recipients Correlates with Higher Chronic Lung Allograft Dysfunction Occurrence

(2016) Julie Di Cristofaro et al.   Journal of Immunology Research

HLA-G*01:04∼UTR3 Recipient Correlates With Lower Survival and Higher Frequency of Chronic Rejection After Lung Transplantation

(2015) J. Di Cristofaro et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Role of TGF-β in the Association Between Primary Graft Dysfunction and Bronchiolitis Obliterans Syndrome

(2015) A. DerHovanessian et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Dysregulated MicroRNA Expression and Chronic Lung Allograft Rejection in Recipients With Antibodies to Donor HLA

(2015) Z. Xu et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Association Between Donor Leukocyte Telomere Length and Survival After Unrelated Allogeneic Hematopoietic Cell Transplantation for Severe Aplastic Anemia

(2015) Shahinaz M. Gadalla et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Interleukin-17 receptor polymorphism predisposes to primary graft dysfunction after lung transplantation

(2015) Jana Somers et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The impact of pre-transplant allosensitization on outcomes after lung transplantation

(2015) James P. Bosanquet et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening

(2015) Bridget D Stuart et al.   NATURE GENETICS

Profiling of peripheral blood mononuclear cells does not accurately predict the bronchiolitis obliterans syndrome after lung transplantation

(2015) Kevin Budding et al.   TRANSPLANT IMMUNOLOGY

Differential Cytokine, Chemokine and Growth Factor Expression in Phenotypes of Chronic Lung Allograft Dysfunction

(2015) Stijn E. Verleden et al.   TRANSPLANTATION

Effect of delayed graft function, acute rejection and chronic allograft dysfunction on kidney allograft telomere length in patients after transplantation: a prospective cohort study

(2015) Leszek Domański et al.   BMC Nephrology

Oxidative stress and DNA methylation regulation in the metabolic syndrome

(2015) Sabrina Yara et al.   Epigenomics

Impact of Pretransplant Anti-HLA Antibodies on Outcomes in Lung Transplant Candidates

(2014) Miae Kim et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of cytokine profile in the differential diagnosis between acute lung rejection and pulmonary infections after lung transplantation†

(2014) Miriam Patella et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

An international ISHLT/ATS/ERS clinical practice guideline: diagnosis and management of bronchiolitis obliterans syndrome

(2014) Keith C. Meyer et al.   EUROPEAN RESPIRATORY JOURNAL

Early donor-specific antibodies in lung transplantation: Risk factors and impact on survival

(2014) Fabio Ius et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

De novo donor-specific HLA antibodies are associated with early and high-grade bronchiolitis obliterans syndrome and death after lung transplantation

(2014) Matthew R. Morrell et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Association of Soluble HLA-G with Acute Rejection Episodes and Early Development of Bronchiolitis Obliterans in Lung Transplantation

(2014) Steven R. White et al.   PLoS One

Mechanistic differences between phenotypes of chronic lung allograft dysfunction after lung transplantation

(2014) Monika I. Suwara et al.   TRANSPLANT INTERNATIONAL

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Telomere shortening in human diseases

(2013) Chiou Mee Kong et al.   FEBS Journal

A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation

(2013) Purvesh Khatri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pre-transplant antibodies to Kα1 tubulin and collagen-V in lung transplantation: Clinical correlations

(2013) Venkataswarup Tiriveedhi et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Aspiration, Localized Pulmonary Inflammation, and Predictors of Early-Onset Bronchiolitis Obliterans Syndrome after Lung Transplantation

(2013) P. Marco Fisichella et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Elevated Bronchoalveolar Lavage Eosinophilia Correlates With Poor Outcome After Lung Transplantation

(2013) Stijn E. Verleden et al.   TRANSPLANTATION

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Altered DNA Methylation Profile in Idiopathic Pulmonary Fibrosis

(2012) Yan Y. Sanders et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antibodies to K-α 1 Tubulin and Collagen V Are Associated With Chronic Rejection After Lung Transplantation

(2012) R. R. Hachem et al.   AMERICAN JOURNAL OF TRANSPLANTATION

MicroRNA 10a Marks Regulatory T Cells

(2012) Lukas T. Jeker et al.   PLoS One

Global Methylation Patterns in Idiopathic Pulmonary Fibrosis

(2012) Einat I. Rabinovich et al.   PLoS One

The Munich-LTX-Score: predictor for survival after lung transplantation

(2011) Patrick Huppmann et al.   CLINICAL TRANSPLANTATION

Alloimmunity-induced autoimmunity as a potential mechanism in the pathogenesis of chronic rejection of human lung allografts

(2011) Deepti Saini et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Expression of miRNAs miR-133b and miR-206 in the Il17a/f Locus Is Co-Regulated with IL-17 Production in αβ and γδ T Cells

(2011) Jan D. Haas et al.   PLoS One

Antibodies to Self-Antigens Predispose to Primary Lung Allograft Dysfunction and Chronic Rejection

(2010) Ankit Bharat et al.   ANNALS OF THORACIC SURGERY

Development of antibodies to human leukocyte antigen precedes development of antibodies to major histocompatibility class I–related chain A and are significantly associated with development of chronic rejection after human lung transplantation

(2010) Nataraju Angaswamy et al.   HUMAN IMMUNOLOGY

Systemic and exhaled cytokine and chemokine profiles are associated with the development of bronchiolitis obliterans syndrome

(2010) Elisabeth A. Kastelijn et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

HLA mismatches influence lung transplant recipient survival, bronchiolitis obliterans and rejection: Implications for donor lung allocation

(2010) Matthias Peltz et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Protection against Bronchiolitis Obliterans Syndrome Is Associated with Allograft CCR7+CD45RA− T Regulatory Cells

(2010) Aric L. Gregson et al.   PLoS One

Decreased Percentage of CD4+FoxP3+ Cells in Bronchoalveolar Lavage From Lung Transplant Recipients Correlates With Development of Bronchiolitis Obliterans Syndrome

(2010) Sangeeta M. Bhorade et al.   TRANSPLANTATION

Posttransplant Bronchiolitis Obliterans Syndrome Is Associated with Bronchial Epithelial to Mesenchymal Transition

(2009) S. Hodge et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Immunohistochemical Study of HLA-G Expression in Lung Transplant Recipients

(2009) O Brugière et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Increased levels of T cell granzyme b in bronchiolitis obliterans syndrome are not suppressed adequately by current immunosuppressive regimens

(2009) S. Hodge et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Prognostic Value of Bronchoalveolar Lavage Neutrophilia in Stable Lung Transplant Recipients

(2009) Claus Neurohr et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Circulating and Intrapulmonary C-Reactive Protein: A Predictor of Bronchiolitis Obliterans Syndrome and Pulmonary Allograft Outcome

(2009) Robin Vos et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Bronchoalveolar Lavage Cell Gene Expression in Acute Lung Rejection: Development of a Diagnostic Classifier

(2009) Jagadish Patil et al.   TRANSPLANTATION

The Role of the IL23/IL17 Axis in Bronchiolitis Obliterans Syndrome After Lung Transplantation

(2008) B. M. Vanaudenaerde et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Pretransplant Panel Reactive Antibodies in Human Lung Transplantation: An Analysis of Over 10,000 Patients

(2008) Ashish S. Shah et al.   ANNALS OF THORACIC SURGERY

Relative Impact of Human Leukocyte Antigen Mismatching and Graft Ischemic Time After Lung Transplantation

(2008) Olivier Brugière et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION