MTOR-mediated interaction between the oocyte and granulosa cells regulates the development and function of both compartments in mice

R-Spondin 2 and WNT/CTNNB1 Signaling Pathways are Required for Porcine Follicle Development and In Vitro Maturation

(2021) Seon-Ung Hwang et al.   Animals

Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice

(2021) Yan Zhang et al.   Nature Communications

R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth

(2020) Marie-Cécile De Cian et al.   CELL DEATH AND DIFFERENTIATION

FSH, Oxytocin and IGF-I Regulate the Expression of Sirtuin 1 in Porcine Ovarian Granulosa Cells

(2020) A SIROTKIN et al.   PHYSIOLOGICAL RESEARCH

The mTOR Pathway in Reproduction: From Gonadal Function to Developmental Coordination

(2019) Bibiana Correia et al.   REPRODUCTION

Role of mTOR Signaling in Female Reproduction

(2019) Zaixin Guo et al.   Frontiers in Endocrinology

Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events

(2018) Marco Conti et al.   HUMAN REPRODUCTION UPDATE

Mechanism of resveratrol in improving ovarian function in a rat model of premature ovarian insufficiency

(2018) Ning Li et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice

(2018) Jing Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian target of rapamycin/eukaryotic initiation factor 4F pathway regulates follicle growth and development of theca cells in mice

(2017) Chao Zhang et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Somatic Cells Initiate Primordial Follicle Activation and Govern the Development of Dormant Oocytes in Mice

(2014) Hua Zhang et al.   CURRENT BIOLOGY

PI3K/PTEN/Akt and TSC/mTOR signaling pathways, ovarian dysfunction, and infertility: an update

(2014) Annu Makker et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Mechanistic target of rapamycin (MTOR) signaling during ovulation in mice

(2014) Dayananda Siddappa et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Growing knowledge of the mTOR signaling network

(2014) Kezhen Huang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Rapamycin prolongs female reproductive lifespan

(2013) Li-li Luo et al.   CELL CYCLE

Oocyte-derived R-spondin2 promotes ovarian follicle development

(2013) Yuan Cheng et al.   FASEB JOURNAL

Rapamycin preserves the follicle pool reserve and prolongs the ovarian lifespan of female rats via modulating mTOR activation and sirtuin expression

(2013) Xing-mei Zhang et al.   GENE

Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytes

(2013) Jing Chen et al.   NATURE CELL BIOLOGY

AKT is involved in granulosa cell autophagy regulation via mTOR signaling during rat follicular development and atresia

(2013) JongYeob Choi et al.   REPRODUCTION

mTOR is required for asymmetric division through small GTPases in mouse oocytes

(2012) Seung-Eun Lee et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Cross Talk Between Estradiol and mTOR Kinase in the Regulation of Ovarian Granulosa Proliferation

(2012) James Yu et al.   Reproductive Sciences

Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition

(2011) J. Chen et al.   GENES & DEVELOPMENT

Mouse Oocytes Enable LH-Induced Maturation of the Cumulus-Oocyte Complex via Promoting EGF Receptor-Dependent Signaling

(2010) You-Qiang Su et al.   MOLECULAR ENDOCRINOLOGY

Granulosa Cell Ligand NPPC and Its Receptor NPR2 Maintain Meiotic Arrest in Mouse Oocytes

(2010) M. Zhang et al.   SCIENCE

Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation

(2009) N. Henriette Uhlenhaut et al.   CELL

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

(2009) D. Adhikari et al.   HUMAN MOLECULAR GENETICS

Disruption of Tsc2 in oocytes leads to overactivation of the entire pool of primordial follicles

(2009) D. Adhikari et al.   MOLECULAR HUMAN REPRODUCTION

MAPK3/1 (ERK1/2) in Ovarian Granulosa Cells Are Essential for Female Fertility

(2009) H.-Y. Fan et al.   SCIENCE

Mouse Oocyte Control of Granulosa Cell Development and Function: Paracrine Regulation of Cumulus Cell Metabolism

(2009) You-Qiang Su et al.   SEMINARS IN REPRODUCTIVE MEDICINE

A Putative Mitotic Checkpoint Dependent on mTOR Function Controls Cell Proliferation and Survival in Ovarian Granulosa Cells

(2008) Aylin Yaba et al.   Reproductive Sciences