c-MYC-USP49-BAG2 axis promotes proliferation and chemoresistance of colorectal cancer cells in vitro

MicroRNA‑325 inhibits the proliferation and induces the apoptosis of T cell acute lymphoblastic leukemia cells in a BAG2‑dependent manner

(2021) Fengyu Wang et al.   Experimental and Therapeutic Medicine

Oncogenic Activity of Glucocorticoid Receptor β Is Controlled by Ubiquitination-Dependent Interaction with USP49 in Glioblastoma Cells

(2021) Yaling Hu et al.   MOLECULAR CANCER RESEARCH

USP29 coordinates MYC and HIF1α stabilization to promote tumor metabolism and progression

(2021) Rongfu Tu et al.   ONCOGENE

BAG2 Promotes Proliferation and Metastasis of Gastric Cancer via ERK1/2 Signaling and Partially Regulated by miR186

(2020) Lisha Sun et al.   Frontiers in Oncology

LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2

(2020) Hua Yu et al.   CELL DEATH AND DIFFERENTIATION

DUB3 deubiquitinates and stabilizes NRF2 in chemotherapy resistance of colorectal cancer

(2019) Qi Zhang et al.   CELL DEATH AND DIFFERENTIATION

USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA

(2019) Liya Ye et al.   PLoS Pathogens

USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability

(2019) Maura Sonego et al.   Science Advances

Over-expression of Bcl2-associated athanogene 2 in oral cancer promotes cellular proliferation and is associated with poor prognosis

(2019) Yi-Song Liu et al.   ARCHIVES OF ORAL BIOLOGY

Deubiquitinating enzymes in cancer stem cells: functions and targeted inhibition for cancer therapy

(2018) Kamini Kaushal et al.   DRUG DISCOVERY TODAY

USP49 participates in the DNA damage response by forming a positive feedback loop with p53

(2018) Rongfu Tu et al.   Cell Death & Disease

Co-chaperone BAG2 Determines the Pro-oncogenic Role of Cathepsin B in Triple-Negative Breast Cancer Cells

(2017) Kyung-Min Yang et al.   Cell Reports

BAG2 structure, function and involvement in disease

(2016) Lixia Qin et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer

(2015) Lukas E. Dow et al.   CELL

miR-191 promotes tumorigenesis of human colorectal cancer through targeting C/EBPβ

(2015) Xiao-Fei Zhang et al.   Oncotarget

BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function

(2015) Xuetian Yue et al.   eLife

Colorectal cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing

(2013) Z. Zhang et al.   GENES & DEVELOPMENT