Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms

Patterned Illumination Techniques in Optogenetics: An Insight Into Decelerating Murine Hearts

(2022) Laura Diaz-Maue et al.   Frontiers in Physiology

Drift and termination of spiral waves in optogenetically modified cardiac tissue at sub-threshold illumination

(2021) Sayedeh Hussaini et al.   eLife

Universal mechanisms for self-termination of rapid cardiac rhythm

(2020) Valentina Biasci et al.   CHAOS

Cardiac optogenetics: a decade of enlightenment

(2020) Emilia Entcheva et al.   Nature Reviews Cardiology

Optogenetic Hyperpolarization of Cardiomyocytes Terminates Ventricular Arrhythmia

(2019) Maximilian Funken et al.   Frontiers in Physiology

Optogenetic Termination of Cardiac Arrhythmia: Mechanistic Enlightenment and Therapeutic Application?

(2019) Philipp Sasse et al.   Frontiers in Physiology

Real-time optical manipulation of cardiac conduction in intact hearts

(2018) M. Scardigli et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sympathetic Nervous Regulation of Calcium and Action Potential Alternans in the Intact Heart

(2018) James Winter et al.   Frontiers in Physiology

Energy-Reduced Arrhythmia Termination Using Global Photostimulation in Optogenetic Murine Hearts

(2018) Raúl A. Quiñonez Uribe et al.   Frontiers in Physiology

Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy

(2017) M. Scardigli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic termination of ventricular arrhythmias in the whole heart: towards biological cardiac rhythm management

(2016) Emile C.A. Nyns et al.   EUROPEAN HEART JOURNAL

Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations

(2016) Tobias Bruegmann et al.   JOURNAL OF CLINICAL INVESTIGATION

All-optical control of cardiac excitation: combined high-resolution optogenetic actuation and optical mapping

(2016) Emilia Entcheva et al.   JOURNAL OF PHYSIOLOGY-LONDON

Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation

(2016) Claudia Crocini et al.   Scientific Reports

Optogenetics for in vivo cardiac pacing and resynchronization therapies

(2015) Udi Nussinovitch et al.   NATURE BIOTECHNOLOGY

Optical control of excitation waves in cardiac tissue

(2015) Rebecca A. B. Burton et al.   Nature Photonics

Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2

(2015) Tania Zaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach

(2014) T. V. Karathanos et al.   EUROPACE

Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model

(2013) John C. Williams et al.   PLoS Computational Biology

Determinants of myocardial conduction velocity: implications for arrhythmogenesis

(2013) James H. King et al.   Frontiers in Physiology

Mathematical modeling mechanisms of arrhythmias in transgenic mouse heart overexpressing TNF-α

(2011) Polina S. Petkova-Kirova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Alternans and Arrhythmias

(2011) James N. Weiss et al.   CIRCULATION RESEARCH

Optogenetic control of heart muscle in vitro and in vivo

(2010) Tobias Bruegmann et al.   NATURE METHODS