FAM98A promotes resistance to 5-fluorouracil in colorectal cancer by suppressing ferroptosis

Metformin induces ferroptosis by targeting miR-324-3p/GPX4 axis in breast cancer

(2021) Yifeng Hou et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Broadening horizons: the role of ferroptosis in cancer

(2021) Xin Chen et al.   Nature Reviews Clinical Oncology

MicroRNA‑26a inhibits cell proliferation and invasion by targeting FAM98A in breast cancer

(2021) Tan Liu et al.   Oncology Letters

Role of stress granules in modulating senescence and promoting cancer progression: special emphasis on glioma

(2021) Debmita Chatterjee et al.   INTERNATIONAL JOURNAL OF CANCER

Metformin may induce ferroptosis by inhibiting autophagy via lncRNA H19 in breast cancer

(2021) Jida Chen et al.   FEBS Open Bio

Coupling of translation quality control and mRNA targeting to stress granules

(2020) Stephanie L. Moon et al.   JOURNAL OF CELL BIOLOGY

FAM98A promotes cancer progression in endometrial carcinoma

(2019) Zenghui Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

Stress granules and neurodegeneration

(2019) Benjamin Wolozin et al.   NATURE REVIEWS NEUROSCIENCE

Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

(2018) Irina Ingold et al.   CELL

FAM98A is localized to stress granules and associates with multiple stress granule-localized proteins

(2018) Kanako Ozeki et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Metformin as an Anticancer Agent

(2018) Ales Vancura et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

FAM98A promotes proliferation of non-small cell lung cancer cells via the P38-ATF2 signaling pathway

(2018) Rui Zheng et al.   Cancer Management and Research

FAM98A associates with DDX1-C14orf166-FAM98B in a novel complex involved in colorectal cancer progression

(2017) Khondker Ayesha Akter et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT

(2017) Yuchao Gu et al.   MOLECULAR CELL

Metformin as an adjuvant treatment for cancer: a systematic review and meta-analysis

(2016) C. Coyle et al.   ANNALS OF ONCOLOGY

Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer

(2016) Jong-Lyel Roh et al.   CANCER LETTERS

Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial

(2016) Takuma Higurashi et al.   LANCET ONCOLOGY

Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation

(2016) Witold Szaflarski et al.   Oncotarget

Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function

(2015) LIANGYU CHEN et al.   ONCOLOGY REPORTS

FAM98A is a novel substrate of PRMT1 required for tumor cell migration, invasion, and colony formation

(2015) Khondker Ayesha Akter et al.   TUMOR BIOLOGY

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

The RNA-Binding Protein DDX1 Promotes Primary MicroRNA Maturation and Inhibits Ovarian Tumor Progression

(2014) Cecil Han et al.   Cell Reports

A divergent calponin homology (NN–CH) domain defines a novel family: implications for evolution of ciliary IFT complex B proteins

(2013) Kenneth B. Schou et al.   BIOINFORMATICS

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules

(2012) Ken Fujimura et al.   NUCLEIC ACIDS RESEARCH

Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial

(2011) Sirwan Hadad et al.   BREAST CANCER RESEARCH AND TREATMENT

DDX1 Is an RNA-Dependent ATPase Involved in HIV-1 Rev Function and Virus Replication

(2011) Stephen P. Edgcomb et al.   JOURNAL OF MOLECULAR BIOLOGY

Metformin Suppresses Colorectal Aberrant Crypt Foci in a Short-term Clinical Trial

(2010) K. Hosono et al.   Cancer Prevention Research

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Worldwide Variations in Colorectal Cancer

(2009) M. M. Center et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Stress granules: the Tao of RNA triage

(2008) Paul Anderson et al.   TRENDS IN BIOCHEMICAL SCIENCES