Multicenter Population Pharmacokinetic Study of Unbound Ceftriaxone in Critically Ill Patients

Population pharmacokinetics of ceftriaxone administered as continuous or intermittent infusion in critically ill patients

(2020) E Leegwater et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Ampicillin and ceftriaxone solution stability at different temperatures useful for outpatient parenteral antimicrobial therapy (OPAT)

(2020) L Herrera-Hidalgo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#

(2020) Mohd H. Abdul-Aziz et al.   INTENSIVE CARE MEDICINE

Are standard dosing regimens of ceftriaxone adapted for critically ill patients with augmented creatinine clearance? A prospective observational study.

(2019) Julien Ollivier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-dose ceftriaxone for bacterial meningitis: optimization of administration scheme based on nomogram

(2019) Matthieu Grégoire et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

β-Lactam pharmacodynamics in Gram-negative bloodstream infections in the critically ill

(2019) Gloria Wong et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A Comparison of Cefazolin Versus Ceftriaxone for the Treatment of Methicillin-Susceptible Staphylococcus aureus Bacteremia in a Tertiary Care VA Medical Center

(2018) Dustin R Carr et al.   Open Forum Infectious Diseases

Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures

(2018) Gloria Wong et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

How to optimize antibiotic pharmacokinetic/pharmacodynamics for Gram-negative infections in critically ill patients

(2018) Aaron J. Heffernan et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Intrapulmonary pharmacokinetics of antibiotics used to treat nosocomial pneumonia caused by gram-negative bacilli: a systematic review

(2018) Aaron J Heffernan et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Tolerability of high-dose ceftriaxone in CNS infections: a prospective multicentre cohort study

(2018) Paul Le Turnier et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Population pharmacokinetics of total and unbound teicoplanin concentrations and dosing simulations in patients with haematological malignancy

(2017) Catherine J Byrne et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Total and unbound ceftriaxone pharmacokinetics in critically ill Australian Indigenous patients with severe sepsis

(2016) Danny Tsai et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Protein binding characteristics and pharmacokinetics of ceftriaxone in intensive care unit patients

(2015) Michael Schleibinger et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Screening of patients with augmented renal clearance in ICU: taking into account the CKD-EPI equation, the age, and the cause of admission

(2015) Stéphanie Ruiz et al.   Annals of Intensive Care

DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current  -Lactam Antibiotic Doses Sufficient for Critically Ill Patients?

(2014) J. A. Roberts et al.   CLINICAL INFECTIOUS DISEASES

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

(2014) Jason A Roberts et al.   LANCET INFECTIOUS DISEASES

Protein Binding of β-Lactam Antibiotics in Critically Ill Patients: Can We Successfully Predict Unbound Concentrations?

(2013) Gloria Wong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Augmented Renal Clearance in the ICU

(2013) Andrew A. Udy et al.   CRITICAL CARE MEDICINE

A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection

(2012) Scott E. Briscoe et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Accurate Detection of Outliers and Subpopulations With Pmetrics, a Nonparametric and Parametric Pharmacometric Modeling and Simulation Package for R

(2012) Michael N. Neely et al.   THERAPEUTIC DRUG MONITORING

Population pharmacokinetics of ceftriaxone in critically ill septic patients: a reappraisal

(2011) Denis Garot et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

The Effects of Hypoalbuminaemia on Optimizing Antibacterial Dosing in Critically Ill Patients

(2010) Marta Ulldemolins et al.   CLINICAL PHARMACOKINETICS

Feedback dose alteration significantly affects probability of pathogen eradication in nosocomial pneumonia

(2009) F. Scaglione et al.   EUROPEAN RESPIRATORY JOURNAL

Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections

(2008) Peggy S. McKinnon et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS