Chemosynthetic ethanolamine plasmalogen stimulates gonadotropin secretion from bovine gonadotrophs by acting as a potential GPR61 agonist

Ins and outs of AlphaFold2 transmembrane protein structure predictions

(2022) Tamás Hegedűs et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Reduced gonadotroph stimulation by ethanolamine plasmalogens in old bovine brains

(2021) Hiroya Kadokawa et al.   Scientific Reports

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity

(2021) Kyle M. Schachtschneider et al.   GeroScience

Artificial intelligence for microbial biotechnology: beyond the hype

(2021) Serina L. Robinson   Microbial Biotechnology

Identification of plasmalogens in Bifidobacterium longum, but not in Bifidobacterium animalis

(2020) Shiro Mawatari et al.   Scientific Reports

Structural basis for GPCR signaling by small polar versus large lipid metabolites—discovery of non-metabolite ligands

(2020) Michael Lückmann et al.   CURRENT OPINION IN CELL BIOLOGY

OPLS3e: Extending Force Field Coverage for Drug-Like Small Molecules

(2019) Katarina Roos et al.   Journal of Chemical Theory and Computation

Overexpression of Orphan Receptor GPR61 Increases cAMP Levels upon Forskolin Stimulation in HEK293 Cells: in vitro and in silico Validation of 5-(Nonyloxy)Tryptamine as a Low-Affinity Inverse Agonist

(2019) Pawel Kozielewicz et al.   PHARMACOLOGY

Influence of brain plasmalogen changes on gonadotropin secretion from the cultured bovine anterior pituitary cells

(2018) O. Kereilwe et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Exploring a new ligand binding site of G protein-coupled receptors

(2018) H.C. Stephen Chan et al.   Chemical Science

Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions

(2017) Atsuro Oishi et al.   Scientific Reports

Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

(2017) Takehiko Fujino et al.   EBioMedicine

SMAD3 Regulates Follicle-stimulating Hormone Synthesis by Pituitary Gonadotrope Cellsin Vivo

(2016) Yining Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic kinases downstream of GPR30 suppress gonadotropin-releasing hormone (GnRH)-induced luteinizing hormone secretion from bovine anterior pituitary cells

(2016) Faidiban O. RUDOLF et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Method for isolating pure bovine gonadotrophs from anterior pituitary using magnetic nanoparticles and anti-gonadotropin-releasing hormone receptor antibody

(2016) Kiran PANDEY et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Neuronal Orphan G-Protein Coupled Receptor Proteins Mediate Plasmalogens-Induced Activation of ERK and Akt Signaling

(2016) Md. Shamim Hossain et al.   PLoS One

Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer’s disease subjects

(2015) Paul L. Wood et al.   ACTA NEUROPSYCHIATRICA

Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer’s disease subjects

(2015) Paul L. Wood et al.   ACTA NEUROPSYCHIATRICA

Gonadotropin-releasing hormone (GnRH) receptors of cattle aggregate on the surface of gonadotrophs and are increased by elevated GnRH concentrations

(2014) Hiroya Kadokawa et al.   ANIMAL REPRODUCTION SCIENCE

An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins

(2014) Wei Yuan et al.   Nature Communications

Development of an ALK2-Biased BMP Type I Receptor Kinase Inhibitor

(2013) Agustin H. Mohedas et al.   ACS Chemical Biology

GPCR Heterodimerization in the Reproductive System: Functional Regulation and Implication for Biodiversity

(2013) Honoo Satake et al.   Frontiers in Endocrinology

Functions of plasmalogen lipids in health and disease

(2012) Nancy E. Braverman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Characterization of metabolic phenotypes of mice lacking GPR61, an orphan G-protein coupled receptor

(2011) Hirohide Nambu et al.   LIFE SCIENCES

Identifying and Characterizing Binding Sites and Assessing Druggability

(2009) Thomas A. Halgren   Journal of Chemical Information and Modeling

The N-terminal domain of GPR61, an orphan G-protein-coupled receptor, is essential for its constitutive activity

(2008) Masaru Toyooka et al.   JOURNAL OF NEUROSCIENCE RESEARCH