Ni‐Catalyzed Divergent Synthesis of 2‐Benzazepine Derivatives via Tunable Cyclization and 1,4‐Acyl Transfer Triggered by Amide N‐C Bond Cleavage

Nickel‐Catalyzed Asymmetric Reductive Carbo‐Carboxylation of Alkenes with CO 2

(2021) Xiao‐Wang Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Indium‐Catalyzed C−F Bond Transformation through Oxymetalation/β‐Fluorine Elimination to Access Fluorinated Isocoumarins

(2021) Tetsuji Yata et al.   CHEMISTRY-A EUROPEAN JOURNAL

Acyclic Twisted Amides

(2021) Guangrong Meng et al.   CHEMICAL REVIEWS

Ni-Catalyzed Ligand-Controlled Regiodivergent Reductive Dicarbofunctionalization of Alkenes

(2021) Qi Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ni-Catalyzed Reductive Arylcyanation of Alkenes

(2021) Hengxu Li et al.   ORGANIC LETTERS

Ni-Catalyzed Reductive Difunctionalization of Alkenes

(2020) Yuanyuan Ping et al.   SYNTHESIS-STUTTGART

Metal-Catalyzed Approaches toward the Oxindole Core

(2020) Austin D. Marchese et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nickel‐Catalyzed Dicarbofunctionalization of Alkenes †

(2020) Yun‐Cheng Luo et al.   CHINESE JOURNAL OF CHEMISTRY

Nickel-Catalyzed Asymmetric Addition of Aromatic Halides to Ketones: Highly Enantioselective Synthesis of Chiral 2,3-Dihydrobenzofurans Containing a Tertiary Alcohol

(2020) Ying Li et al.   ORGANIC LETTERS

Nickel-Catalyzed Enantioselective Reductive Cross-Coupling Reactions

(2020) Kelsey E. Poremba et al.   ACS Catalysis

Nickel-Catalyzed Dicarbofunctionalization of Alkenes

(2020) Xiaoxu Qi et al.   ACS Catalysis

Ni-Catalyzed Reductive Antiarylative Cyclization of Alkynones

(2020) Zhijun Zhou et al.   ORGANIC LETTERS

Synthesis of Indanones and Spiroindanones by Diastereoselective Annulation Based on a Hydrogen Autotransfer Strategy

(2020) Yate Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective Photocycloaddition of Saccharin Anion to π-Systems: Continuous-Flow Synthesis of Benzosultams

(2019) Francisco N. Figueroa et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Chemoselective, Transition-Metal-Free Transamidation of Unactivated Amides and Direct Amidation of Alkyl Esters by N–C/O–C Cleavage

(2019) Guangchen Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ni-Catalyzed Regio- and Enantioselective Domino Reductive Cyclization: One-Pot Synthesis of 2,3-Fused Cyclopentannulated Indolines

(2019) Yuanyuan Ping et al.   ACS Catalysis

Ni-Catalyzed Reductive Arylacylation of Alkenes toward Carbonyl-Containing Oxindoles

(2019) Sheng Xu et al.   ORGANIC LETTERS

Nickel-Catalyzed Enantioselective Reductive Aryl Fluoroalkenylation of Alkenes

(2019) Teng Ma et al.   ACS Catalysis

Transition‐Metal‐Free Activation of Amides by N−C Bond Cleavage

(2019) Guangchen Li et al.   CHEMICAL RECORD

Kinetically Controlled, Highly Chemoselective Acylation of Functionalized Grignard Reagents with Amides by N−C Cleavage

(2019) Guangchen Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Construction of Quaternary Stereocenters by Palladium-Catalyzed Carbopalladation-Initiated Cascade Reactions

(2018) Yuanyuan Ping et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Directed Divergent Synthesis of Carbo- and Heterocyclic Ring Systems

(2018) Yen-Chun Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery and synthesis of 6,7,8,9-tetrahydro-5 H -pyrido[4,3- c ]azepin-5-one-based novel chemotype CCR2 antagonists via scaffold hopping strategy

(2018) Li-Huai Qin et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Fluoride-Catalyzed Esterification of Amides

(2018) Hongxiang Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Acyl-glutarimides: Resonance and Proton Affinities of Rotationally-Inverted Twisted Amides Relevant to N–C(O) Cross-Coupling

(2018) Roman Szostak et al.   ORGANIC LETTERS

Nickel-Catalyzed Domino Heck Cyclization/Suzuki Coupling for the Synthesis of 3,3-Disubstituted Oxindoles

(2018) Yuxiu Li et al.   ORGANIC LETTERS

Amide activation: an emerging tool for chemoselective synthesis

(2018) Daniel Kaiser et al.   CHEMICAL SOCIETY REVIEWS

Ni-Catalyzed Enantioselective Reductive Diarylation of Activated Alkenes by Domino Cyclization/Cross-Coupling

(2018) Kuai Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Resonance Destabilization in N-Acylanilines (Anilides): Electronically-Activated Planar Amides of Relevance in N–C(O) Cross-Coupling

(2017) Roman Szostak et al.   JOURNAL OF ORGANIC CHEMISTRY

Breaking Amides using Nickel Catalysis

(2017) Jacob E. Dander et al.   ACS Catalysis

Stereospecific and stereoconvergent cross-couplings between alkyl electrophiles

(2017) Erika L. Lucas et al.   Nature Reviews Chemistry

Nickel-Catalyzed Esterification of Aliphatic Amides

(2016) Liana Hie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient Synthesis of Diaryl Ketones by Nickel-Catalyzed Negishi Cross-Coupling of Amides by Carbon-Nitrogen Bond Cleavage at Room Temperature Accelerated by a Solvent Effect

(2016) Shicheng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Acylsaccharins: Stable Electrophilic Amide-Based Acyl Transfer Reagents in Pd-Catalyzed Suzuki–Miyaura Coupling via N–C Cleavage

(2016) Chengwei Liu et al.   ORGANIC LETTERS

Chemoselective Ketone Synthesis by the Addition of Organometallics to N-Acylazetidines

(2016) Chengwei Liu et al.   ORGANIC LETTERS

Nickel-Catalyzed Diaryl Ketone Synthesis by N–C Cleavage: Direct Negishi Cross-Coupling of Primary Amides by Site-Selective N,N-Di-Boc Activation

(2016) Shicheng Shi et al.   ORGANIC LETTERS

Palladium-Catalyzed Suzuki–Miyaura Cross-Coupling of Amides via Site-Selective N–C Bond Cleavage by Cooperative Catalysis

(2016) Guangrong Meng et al.   ACS Catalysis

Nickel-Catalyzed Reductive Couplings

(2016) Xuan Wang et al.   Topics in Current Chemistry

Methods and Mechanisms for Cross-Electrophile Coupling of Csp2 Halides with Alkyl Electrophiles

(2015) Daniel J. Weix   ACCOUNTS OF CHEMICAL RESEARCH

Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules

(2015) Stefan A. Ruider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acylative Suzuki coupling of amides: acyl-nitrogen activation via synergy of independently modifiable activating groups

(2015) Xijing Li et al.   CHEMICAL COMMUNICATIONS

Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds

(2015) Liana Hie et al.   NATURE

Nickel-catalysed Suzuki–Miyaura coupling of amides

(2015) Nicholas A. Weires et al.   Nature Chemistry

Sterically Controlled Pd-Catalyzed Chemoselective Ketone Synthesis via N–C Cleavage in Twisted Amides

(2015) Guangrong Meng et al.   ORGANIC LETTERS

Nickel-catalyzed reductive coupling of alkyl halides with other electrophiles: concept and mechanistic considerations

(2015) Jun Gu et al.   Organic Chemistry Frontiers

Synthesis of Isoquinolin-4-ols by Palladium-Catalysed Intramolecular Nucleophilic Addition of Aryl Iodides to Aldehydes

(2014) Daniel Solé et al.   ADVANCED SYNTHESIS & CATALYSIS

Reductive Cross-Coupling Reactions between Two Electrophiles

(2014) Christiane E. I. Knappke et al.   CHEMISTRY-A EUROPEAN JOURNAL

Metal-Catalyzed Reductive Coupling Reactions of Organic Halides with Carbonyl-Type Compounds

(2014) Toni Moragas et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cross-Electrophile Coupling: Principles of Reactivity and Selectivity

(2014) Daniel A. Everson et al.   JOURNAL OF ORGANIC CHEMISTRY

Endo-Selective Pd-Catalyzed Silyl Methyl Heck Reaction

(2014) Marvin Parasram et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemistry of Bridged Lactams and Related Heterocycles

(2013) Michal Szostak et al.   CHEMICAL REVIEWS

Direct Transformation of Secondary Amides into Secondary Amines: Triflic Anhydride Activated Reductive Alkylation

(2012) Kai-Jiong Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Selective Synthesis

(2012) Jessada Mahatthananchai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemoselective synthesis of ketones and ketimines by addition of organometallic reagents to secondary amides

(2012) William S. Bechara et al.   Nature Chemistry

Radioprotection by Hymenialdisine-Derived Checkpoint Kinase 2 Inhibitors

(2011) Thu N. T. Nguyen et al.   ACS Chemical Biology

A Facile Pathway to Enantiomerically Enriched 3-Hydroxy-2-Oxindoles: Asymmetric Intramolecular Arylation of α-Keto Amides Catalyzed by a Palladium-DifluorPhos Complex

(2011) Liang Yin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Intramolecular Nucleophilic Addition of Aryl or Vinyl Chlorides to α-Ketoamides Through CCl Bond Activation

(2011) Jin-Xiu Hu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors

(2011) Ashit K. Ganguly et al.   JOURNAL OF MEDICINAL CHEMISTRY

Direct, One-pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents through Lactam/Amide Activation

(2010) Kai-Jiong Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and synthesis of cyclic sulfonamides and sulfamates as new calcium sensing receptor agonists

(2010) Lionel Kiefer et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chemoselectivity and the Curious Reactivity Preferences of Functional Groups

(2009) Nicholas A. Afagh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 3-hydroxyoxindoles by Pd-catalysed intramolecular nucleophilic addition of aryl halides to α-ketoamides

(2009) Yi-Xia Jia et al.   CHEMICAL COMMUNICATIONS

Intramolecular Pd(0)-Catalyzed Reactions of β-(2-Iodoanilino) Carboxamides: Enolate Arylation and Nucleophilic Substitution at the Carboxamide Group

(2008) Daniel Solé et al.   JOURNAL OF ORGANIC CHEMISTRY