Small Molecules Modulate Liquid‐to‐Solid Transitions in Phase‐Separated Tau Condensates

Conformational Expansion of Tau in Condensates Promotes Irreversible Aggregation

(2021) Jitao Wen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Determinants for Fusion Speed of Biomolecular Droplets

(2020) Archishman Ghosh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α-Synuclein aggregation nucleates through liquid–liquid phase separation

(2020) Soumik Ray et al.   Nature Chemistry

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions

(2019) Yanxian Lin et al.   eLife

Liquid–Liquid Phase Separation Is Driven by Large-Scale Conformational Unwinding and Fluctuations of Intrinsically Disordered Protein Molecules

(2019) Anupa Majumdar et al.   Journal of Physical Chemistry Letters

Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain

(2019) Anastasia C. Murthy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

In vitro 0N4R tau fibrils contain a monomorphic β-sheet core enclosed by dynamically heterogeneous fuzzy coat segments

(2019) Aurelio J. Dregni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interplay between Short-Range Attraction and Long-Range Repulsion Controls Reentrant Liquid Condensation of Ribonucleoprotein–RNA Complexes

(2019) Ibraheem Alshareedah et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

Tau protein liquid–liquid phase separation can initiate tau aggregation

(2018) Susanne Wegmann et al.   EMBO JOURNAL

Influence of Ion Solvation on the Properties of Electrolyte Solutions

(2018) Marat Andreev et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Affinity of IDPs to their targets is modulated by ion-specific changes in kinetics and residual structure

(2017) Basile I. M. Wicky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TrimethylamineN-oxide stabilizes proteins via a distinct mechanism compared with betaine and glycine

(2017) Yi-Ting Liao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Competition between crystal and fibril formation in molecular mutations of amyloidogenic peptides

(2017) Nicholas P. Reynolds et al.   Nature Communications

Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase

(2017) Amayra Hernández-Vega et al.   Cell Reports

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Controlled Particle Collision Leads to Direct Observation of Docking and Fusion of Lipid Droplets in an Optical Trap

(2014) Chiran Ghimire et al.   LANGMUIR

Molecular mechanism of Thioflavin-T binding to amyloid fibrils

(2010) Matthew Biancalana et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Hofmeister effects: an explanation for the impact of ionic liquids on biocatalysis

(2009) Zhen Yang   JOURNAL OF BIOTECHNOLOGY