A novel phenotype‐based drug‐induced liver injury causality assessment tool ( DILI‐CAT ) allows for signal confirmation in early drug development

Overview of Causality Assessment for Drug-Induced Liver Injury (DILI) in Clinical Trials

(2021) Juliana Hey-Hadavi et al.   DRUG SAFETY

Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018

(2020) Olivier J. Wouters et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Monocyte-Derived Hepatocyte-Like Cell Test: A Novel Tool for in vitro Identification of Drug-Induced Liver Injury in Patients with Herbal or Dietary Supplements

(2020) Sabine Weber et al.   DIGESTION

EASL Clinical Practice Guidelines: Drug-induced liver injury

(2019) Raúl Andrade et al.   JOURNAL OF HEPATOLOGY

Iberogast-Induced Acute Liver Failure—Reexposure and In Vitro Assay Support Causality

(2019) Florian Gerhardt et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Development and Validation of a Test to Identify Drugs That Cause Idiosyncratic Drug-Induced Liver Injury

(2018) Andreas Benesic et al.   Clinical Gastroenterology and Hepatology

Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury

(2017) Ayako Suzuki et al.   LIVER INTERNATIONAL

RUCAM in Drug and Herb Induced Liver Injury: The Update

(2015) Gaby Danan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Causality Assessment for Suspected DILI During Clinical Phases of Drug Development

(2014) Arie Regev et al.   DRUG SAFETY

Predicting potential liver toxicity from phase 2 data: a case study with ximelagatran

(2014) Harry Southworth   STATISTICS IN MEDICINE

Case Definition and Phenotype Standardization in Drug-Induced Liver Injury

(2011) G P Aithal et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Standardization of nomenclature and causality assessment in drug-induced liver injury: Summary of a clinical research workshop

(2010) Robert J. Fontana et al.   HEPATOLOGY

Causality assessment in drug-induced liver injury using a structured expert opinion process: Comparison to the Roussel-Uclaf causality assessment method

(2010) Don C. Rockey et al.   HEPATOLOGY

Reliability of the Roussel Uclaf Causality Assessment Method for assessing causality in drug-induced liver injury

(2008) James Rochon et al.   HEPATOLOGY