AR cooperates with SMAD4 to maintain skeletal muscle homeostasis

Perturbed BMP signaling and denervation promote muscle wasting in cancer cachexia

(2021) Roberta Sartori et al.   Science Translational Medicine

Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity

(2021) Wooi F. Lim et al.   Science Advances

The Role of Bone Morphogenetic Protein 7 (BMP-7) in Inflammation in Heart Diseases

(2020) Chandrakala Aluganti Narasimhulu et al.   Cells

Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism

(2020) Mathilde Chivet et al.   Cells

MEF2 impairment underlies skeletal muscle atrophy in polyglutamine disease

(2020) Samir R. Nath et al.   ACTA NEUROPATHOLOGICA

Side chain to main chain hydrogen bonds stabilize a polyglutamine helix in a transcription factor

(2019) Albert Escobedo et al.   Nature Communications

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70

(2019) Liqing Luo et al.   Cell Reports

Beyond motor neurons: expanding the clinical spectrum in Kennedy’s disease

(2018) Raquel Manzano et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

From gene to therapy in spinal and bulbar muscular atrophy: Are we there yet?

(2018) Maria Pennuto et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

SMAD4 feedback regulates the canonical TGF-β signaling pathway to control granulosa cell apoptosis

(2018) Xing Du et al.   Cell Death & Disease

Robust model-based analysis of single-particle tracking experiments with Spot-On

(2018) Anders S Hansen et al.   eLife

A randomized trial of adjunct testosterone for cancer-related muscle loss in men and women

(2018) Traver J. Wright et al.   Journal of Cachexia Sarcopenia and Muscle

Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction

(2018) Samir R. Nath et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

(2018) Ann Boija et al.   CELL

Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients

(2017) Doriana Borgia et al.   HUMAN MOLECULAR GENETICS

Body Image Disorders and Abuse of Anabolic-Androgenic Steroids Among Men

(2017) Harrison G. Pope et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Bone Morphogenetic Proteins and myostatin pathways: key mediator of human sarcopenia

(2017) Manuel Scimeca et al.   Journal of Translational Medicine

Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet

(2016) Anna Rocchi et al.   ACTA NEUROPATHOLOGICA

MultiQC: summarize analysis results for multiple tools and samples in a single report

(2016) Philip Ewels et al.   BIOINFORMATICS

PPARγ regulates inflammatory reaction by inhibiting the MAPK/NF-κB pathway in C2C12 skeletal muscle cells

(2016) Jeong-Seok Kim et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy

(2016) Naemeh Pourshafie et al.   MOLECULAR THERAPY

The role of GATA2 in lethal prostate cancer aggressiveness

(2016) Veronica Rodriguez-Bravo et al.   Nature Reviews Urology

Selective Neuromuscular Denervation in Taiwanese Severe SMA Mouse Can Be Reversed by Morpholino Antisense Oligonucleotides

(2016) Te-Lin Lin et al.   PLoS One

Muscle as a “Mediator” of Systemic Metabolism

(2015) Kedryn K. Baskin et al.   Cell Metabolism

Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy

(2015) Giulia Milan et al.   Nature Communications

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells

(2014) Jiji Chen et al.   CELL

Fold Change of Nuclear NF-κB Determines TNF-Induced Transcription in Single Cells

(2014) Robin E.C. Lee et al.   MOLECULAR CELL

Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA

(2014) Constanza J Cortes et al.   NATURE NEUROSCIENCE

Muscle Matters in Kennedy’s Disease

(2014) Carlo Rinaldi et al.   NEURON

TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease

(2014) Roberta Sartori et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Intramuscular adipogenesis is inhibited by myo-endothelial progenitors with functioning Bmpr1a signalling

(2014) Ping Huang et al.   Nature Communications

Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy

(2014) Andrew P. Lieberman et al.   Cell Reports

Transcription Factors Modulate c-Fos Transcriptional Bursts

(2014) Adrien Senecal et al.   Cell Reports

Mechanisms regulating skeletal muscle growth and atrophy

(2013) Stefano Schiaffino et al.   FEBS Journal

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

(2013) Catherine E. Winbanks et al.   JOURNAL OF CELL BIOLOGY

Understanding nuclear receptor form and function using structural biology

(2013) Fraydoon Rastinejad et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Anabolic Steroid Induced Hypogonadism in Young Men

(2013) Robert M. Coward et al.   JOURNAL OF UROLOGY

BMP signaling controls muscle mass

(2013) Roberta Sartori et al.   NATURE GENETICS

FISH-quant: automatic counting of transcripts in 3D FISH images

(2013) Florian Mueller et al.   NATURE METHODS

Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype

(2013) J L L Robinson et al.   ONCOGENE

More than a bystander: the contributions of intrinsic skeletal muscle defects in motor neuron diseases

(2013) Justin G. Boyer et al.   Frontiers in Physiology

Muscles, exercise and obesity: skeletal muscle as a secretory organ

(2012) Bente K. Pedersen et al.   Nature Reviews Endocrinology

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evolution and function of CAG/polyglutamine repeats in protein–protein interaction networks

(2012) Martin H. Schaefer et al.   NUCLEIC ACIDS RESEARCH

RNA-Seq analysis in MeV

(2011) E. A. Howe et al.   BIOINFORMATICS

BMP signaling balances proliferation and differentiation of muscle satellite cell descendants

(2011) Melanie Friedrichs et al.   BMC CELL BIOLOGY

Automated multidimensional single molecule fluorescence microscopy feature detection and tracking

(2011) Daniel J. Rolfe et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Higher Testosterone Levels Are Associated with Less Loss of Lean Body Mass in Older Men

(2011) Erin S. LeBlanc et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Inefficient skeletal muscle repair in inhibitor of differentiation knockout mice suggests a crucial role for BMP signaling during adult muscle regeneration

(2010) Jared L. Clever et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

(2010) Viviana Moresi et al.   CELL

BMP signalling permits population expansion by preventing premature myogenic differentiation in muscle satellite cells

(2010) Y Ono et al.   CELL DEATH AND DIFFERENTIATION

Bmp Signaling at the Tips of Skeletal Muscles Regulates the Number of Fetal Muscle Progenitors and Satellite Cells during Development

(2010) Hui Wang et al.   DEVELOPMENTAL CELL

Disrupted Transforming Growth Factor-  Signaling in Spinal and Bulbar Muscular Atrophy

(2010) M. Katsuno et al.   JOURNAL OF NEUROSCIENCE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination

(2009) T. Fei et al.   GENOME RESEARCH

ChIP-seq: Using high-throughput sequencing to discover protein–DNA interactions

(2009) Dominic Schmidt et al.   METHODS

HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis

(2008) Georgyi V. Los et al.   ACS Chemical Biology

Spinal and bulbar muscular atrophy: Skeletal muscle pathology in male patients and heterozygous females

(2007) Gianni Sorarù et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES