A Single-Molecule View at Nanoparticle Targeting Selectivity: Correlating Ligand Functionality and Cell Receptor Density

How Reactivity Variability of Biofunctionalized Particles Is Determined by Superpositional Heterogeneities

(2021) Rafiq M. Lubken et al.   ACS Nano

Controlling Conjugated Antibodies at the Molecular Level for Active Targeting Nanoparticles toward HER2-Positive Cancer Cells

(2021) Mingyang Li et al.   MOLECULAR PHARMACEUTICS

Density of Conjugated Antibody Determines the Extent of Fc Receptor Dependent Capture of Nanoparticles by Liver Sinusoidal Endothelial Cells

(2021) Cinja Kappel et al.   ACS Nano

Correlating Super-Resolution Microscopy and Transmission Electron Microscopy Reveals Multiparametric Heterogeneity in Nanoparticles

(2021) Teodora Andrian et al.   NANO LETTERS

Quantitative Study of the Interaction of Multivalent Ligand-Modified Nanoparticles with Breast Cancer Cells with Tunable Receptor Density

(2020) Jing Wang et al.   ACS Nano

Functionalizing nanoparticles with cancer-targeting antibodies: A comparison of strategies

(2020) A.C. Marques et al.   JOURNAL OF CONTROLLED RELEASE

Aptamers with tunable affinity enable single‐molecule tracking and localization of membrane receptors on living cancer cells

(2020) Pietro Delcanale et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

A quantitative view on multivalent nanomedicine targeting

(2020) Laura Woythe et al.   ADVANCED DRUG DELIVERY REVIEWS

Super-resolution microscopy as a powerful tool to study complex synthetic materials

(2019) Silvia Pujals et al.   Nature Reviews Chemistry

About samples, giving examples: Optimized Single Molecule Localization Microscopy

(2019) Angélique Jimenez et al.   METHODS

A stochastic view on surface inhomogeneity of nanoparticles

(2019) R. A. J. Post et al.   Nature Communications

Ligand density on nanoparticles: A parameter with critical impact on nanomedicine

(2019) Alaaldin M. Alkilany et al.   ADVANCED DRUG DELIVERY REVIEWS

Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T

(2019) Thomas Nerreter et al.   Nature Communications

Super-resolution Microscopy for Nanomedicine Research

(2019) Silvia Pujals et al.   ACS Nano

Quantifying the Ligand-Coated Nanoparticle Delivery to Cancer Cells in Solid Tumours

(2018) Qin Dai et al.   ACS Nano

Quantification of ligand density and stoichiometry on the surface of liposomes using single-molecule fluorescence imaging

(2018) Lisa Belfiore et al.   JOURNAL OF CONTROLLED RELEASE

Characterization of nanomedicines: A reflection on a field under construction needed for clinical translation success

(2018) Jean-Baptiste Coty et al.   JOURNAL OF CONTROLLED RELEASE

Nanoscale Mapping Functional Sites on Nanoparticles by Points Accumulation for Imaging in Nanoscale Topography (PAINT)

(2018) Pietro Delcanale et al.   ACS Nano

Direct immunoassays and their performance – theoretical modelling of the effects of antibody orientation and associated kinetics

(2018) Dana Mackey et al.   Integrative Biology

Single molecule localization microscopy coupled with touch preparation for the quantification of trastuzumab-bound HER2

(2018) Steven J. Tobin et al.   Scientific Reports

Conserved effects and altered trafficking of Cetuximab antibodies conjugated to gold nanoparticles with precise control of their number and orientation

(2017) Lorena García-Fernández et al.   Nanoscale

Turning single-molecule localization microscopy into a quantitative bioanalytical tool

(2017) Philip R Nicovich et al.   Nature Protocols

Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona

(2017) Natalia Feiner-Gracia et al.   Small

Antibody fragments as nanoparticle targeting ligands: a step in the right direction

(2017) Daniel A. Richards et al.   Chemical Science

Orientation and characterization of immobilized antibodies for improved immunoassays (Review)

(2017) Nicholas G. Welch et al.   Biointerphases

Recent Advances in the Generation of Antibody-Nanomaterial Conjugates

(2017) Amal J. Sivaram et al.   Advanced Healthcare Materials

HER2 signaling regulates HER2 localization and membrane retention

(2017) Jaekwang Jeong et al.   PLoS One

EGFR targeted thermosensitive liposomes: A novel multifunctional platform for simultaneous tumor targeted and stimulus responsive drug delivery

(2016) Azadeh Haeri et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Mapping of Molecular Structure of the Nanoscale Surface in Bionanoparticles

(2016) Luciana M. Herda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Constructing bifunctional nanoparticles for dual targeting: improved grafting and surface recognition assessment of multiple ligand nanoparticles

(2016) Maria Cristina Lo Giudice et al.   Nanoscale

In situ characterization of nanoparticle biomolecular interactions in complex biological media by flow cytometry

(2016) Maria Cristina Lo Giudice et al.   Nature Communications

Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies

(2016) Miriam Colombo et al.   Nature Communications

Size and surface chemistry of nanoparticles lead to a variant behavior in the unfolding dynamics of human carbonic anhydrase

(2015) Irem Nasir et al.   Nanoscale

Super-Resolution Imaging of Plasma Membrane Glycans

(2014) Sebastian Letschert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanisms of Nanoparticle Internalization and Transport Across an Intestinal Epithelial Cell Model: Effect of Size and Surface Charge

(2014) Azzah M. Bannunah et al.   MOLECULAR PHARMACEUTICS

Dependence of nanoparticle-cell recognition efficiency on the surface orientation of scFv targeting ligands

(2013) Serena Mazzucchelli et al.   Biomaterials Science

Effect of ligand density, receptor density, and nanoparticle size on cell targeting

(2012) Drew R. Elias et al.   Nanomedicine-Nanotechnology Biology and Medicine

Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities

(2012) Z. Cheng et al.   SCIENCE

Heterogeneous Ligand–Nanoparticle Distributions: A Major Obstacle to Scientific Understanding and Commercial Translation

(2011) Douglas G. Mullen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Taking Advantage of Unspecific Interactions to Produce Highly Active Magnetic Nanoparticle−Antibody Conjugates

(2011) Sara Puertas et al.   ACS Nano

The Complex Role of Multivalency in Nanoparticles Targeting the Transferrin Receptor for Cancer Therapies

(2010) Jin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY